iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108298

Ensembl Protein ID

SPBC2D10.12.1:pep

UniProt Accession

O74803; RHP23_SCHPO

Genbank Protein ID

AAD51975.1; CAA21170.1

Protein Name

UV excision repair protein rhp23; RAD23 homolog

Genbank Nucleotide ID

AF174293; CU329671

Gene Name

rhp23; SPBC2D10.12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC2D10.12	SPBC2D10.12.1	SPBC2D10.12.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/UBA	UBA	11584278; 23038266
ULD/UDP/UBQ/UBQ_PIM	UBQ_PIM	12826399; 23038266

Classification

Family	E-value	Score	Start	End
UBD/Alpha-Helix/UBA	6.70e-24	81.4	147	185
ULD/UDP/UBQ/UBQ_PIM	1.50e-26	90.3	1	76

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           ++ ++e++veMG++r+e+ +a+raa+nn+++AveyLl+g
   Q: 147  RNVAVENMVEMGYERSEVERAMRAAFNNPDRAVEYLLTG 185
           6789*********************************97 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefel.evseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           m+lt+k+l++++f + +vs d++++elKeki++++++++e+qkLIy+G+iL Dd+t+ e++ik++++++++v+++k
   Q: 1    MNLTFKNLQQQKFVIsDVSADTKISELKEKIQTQQNYEVERQKLIYSGRILADDKTVGEYNIKEQDFIVCMVSRPK 76
           89**********8888*********************************************************987 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Protects ubiquitin chains against dissambly by deubiquitinating enzymes thereby promoting protein degradation.

Protein Sequence
(Fasta)

MNLTFKNLQQ QKFVISDVSA DTKISELKEK IQTQQNYEVE RQKLIYSGRI LADDKTVGEY 60
NIKEQDFIVC MVSRPKTSTS TPKSAASPAP NPPASVPEKK VEAPSSTVAE STSTTQTVAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCTACCTT GACAATTATT CTCTGATGCA ACGTTTTTTC AAAGAGGTTT TCATTACTAT 60
ACATTTACCC ACTACGCCAA ATTTGCTTTG AAAATGAATT TGACATTCAA AAATCTACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway

Interpro

IPR004806--Rad23
IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR015360--XPC-bd

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin
PF09280--XPC-binding

PRINTS

PR01839--RAD23PROTEIN

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0031593--F:polyubiquitin binding
GO:0043130--F:ubiquitin binding
GO:0042177--P:negative regulation of protein catabolic process
GO:0006289--P:nucleotide-excision repair
GO:0016567--P:protein ubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

spo:SPBC2D10.12

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000126	Aegilops tauschii	32.29	9.00e-33	132.00
IUUC-Aml-001195	Ailuropoda melanoleuca	44.93	1.00e-15	75.50
IUUC-Atr-002756	Amborella trichopoda	35.66	3.00e-43	166.00
IUUC-Apl-003371	Anas platyrhynchos	40.46	3.00e-28	117.00
IUUC-Aca-004704	Anolis carolinensis	33.16	1.00e-32	131.00
IUUC-Aly-005694	Arabidopsis lyrata	36.36	5.00e-49	186.00
IUUC-Ath-007157	Arabidopsis thaliana	35.75	7.00e-47	179.00
IUUC-Ago-007830	Ashbya gossypii	28.84	5.00e-33	133.00
IUUC-Acl-008212	Aspergillus clavatus	44.42	1.00e-60	224.00
IUUC-Afl-008605	Aspergillus flavus	47.37	1.00e-44	172.00
IUUC-Afu-008877	Aspergillus fumigatus	44.44	2.00e-62	231.00
IUUC-Ani-009460	Aspergillus nidulans	46.63	4.00e-64	236.00
IUUC-Aor-010032	Aspergillus oryzae	42.56	1.00e-61	228.00
IUUC-Ate-010458	Aspergillus terreus	43.27	3.00e-59	220.00
IUUC-Ame-011107	Astyanax mexicanus	45.16	7.00e-15	72.80
IUUC-Bgr-012056	Blumeria graminis	41.75	9.00e-32	129.00
IUUC-Bta-012922	Bos taurus	41.53	2.00e-27	114.00
IUUC-Bci-013933	Botrytis cinerea	44.88	3.00e-59	220.00
IUUC-Bdi-014718	Brachypodium distachyon	43.55	8.00e-25	105.00
IUUC-Bol-015272	Brassica oleracea	34.86	2.00e-47	181.00
IUUC-Bra-016970	Brassica rapa	37.82	5.00e-49	186.00
IUUC-Cel-018364	Caenorhabditis elegans	28.80	7.00e-24	102.00
IUUC-Cja-018772	Callithrix jacchus	41.13	2.00e-27	114.00
IUUC-Cfa-020683	Canis familiaris	45.19	3.00e-15	73.90
IUUC-Cpo-022145	Cavia porcellus	52.03	2.00e-18	84.70
IUUC-Cre-022810	Chlamydomonas reinhardtii	35.71	4.00e-23	100.00
IUUC-Csa-023714	Chlorocebus sabaeus	39.65	2.00e-28	118.00
IUUC-Cho-024814	Choloepus hoffmanni	46.97	6.00e-16	76.30
IUUC-Cin-025741	Ciona intestinalis	32.17	2.00e-24	104.00
IUUC-Csv-025823	Ciona savignyi	33.45	4.00e-25	105.00
IUUC-Cgl-026495	Colletotrichum gloeosporioides	39.78	2.00e-30	124.00
IUUC-Cne-027056	Cryptococcus neoformans	38.66	4.00e-26	110.00
IUUC-Cme-027260	Cyanidioschyzon merolae	26.36	2.00e-28	117.00
IUUC-Dre-028209	Danio rerio	34.64	6.00e-45	172.00
IUUC-Dno-029543	Dasypus novemcinctus	41.13	5.00e-27	113.00
IUUC-Dor-030358	Dipodomys ordii	40.16	4.00e-31	126.00
IUUC-Dse-031336	Dothistroma septosporum	66.67	4.00e-33	133.00
IUUC-Dme-032027	Drosophila melanogaster	35.19	3.00e-43	167.00
IUUC-Ete-032583	Echinops telfairi	40.18	5.00e-15	73.60
IUUC-Eca-034243	Equus caballus	42.56	3.00e-27	114.00
IUUC-Eeu-034721	Erinaceus europaeus	36.77	8.00e-15	72.40
IUUC-Fca-035679	Felis catus	41.13	7.00e-27	112.00
IUUC-Fal-037148	Ficedula albicollis	41.13	5.00e-28	116.00
IUUC-Fox-037960	Fusarium oxysporum	46.32	2.00e-35	141.00
IUUC-Fso-038107	Fusarium solani	49.74	9.00e-38	148.00
IUUC-Gmo-039080	Gadus morhua	48.39	5.00e-18	83.20
IUUC-Ggr-040116	Gaeumannomyces graminis	58.00	5.00e-30	122.00
IUUC-Gga-040544	Gallus gallus	36.56	2.00e-27	114.00
IUUC-Gac-042298	Gasterosteus aculeatus	33.33	2.00e-43	167.00
IUUC-Gma-044245	Glycine max	35.18	9.00e-49	185.00
IUUC-Ggo-045125	Gorilla gorilla	39.03	2.00e-27	114.00
IUUC-Hsa-046519	Homo sapiens	39.03	2.00e-27	114.00
IUUC-Hvu-047832	Hordeum vulgare	38.27	3.00e-33	134.00
IUUC-Itr-048295	Ictidomys tridecemlineatus	45.19	4.00e-15	73.60
IUUC-Kpa-049314	Komagataella pastoris	38.80	2.00e-56	210.00
IUUC-Lch-050553	Latimeria chalumnae	51.18	2.00e-13	68.60
IUUC-Lpe-051087	Leersia perrieri	37.20	6.00e-35	139.00
IUUC-Loc-051758	Lepisosteus oculatus	37.08	7.00e-24	102.00
IUUC-Lma-053328	Leptosphaeria maculans	54.05	1.00e-15	71.60
IUUC-Laf-054293	Loxodonta africana	42.15	8.00e-27	112.00
IUUC-Mcc-055600	Macaca mulatta	40.50	2.00e-28	117.00
IUUC-Meu-056459	Macropus eugenii	40.16	4.00e-32	130.00
IUUC-Mor-057287	Magnaporthe oryzae	42.56	2.00e-33	134.00
IUUC-Mpo-057609	Magnaporthe poae	60.68	5.00e-28	116.00
IUUC-Mtr-058239	Medicago truncatula	34.82	3.00e-48	183.00
IUUC-Mla-058961	Melampsora laricipopulina	46.51	1.00e-28	119.00
IUUC-Mvi-060220	Microbotryum violaceum	36.89	3.00e-25	107.00
IUUC-Mmr-061159	Microcebus murinus	40.96	7.00e-27	112.00
IUUC-Mdo-062742	Monodelphis domestica	34.29	8.00e-48	182.00
IUUC-Mmu-063929	Mus musculus	34.06	3.00e-46	176.00
IUUC-Mac-064724	Musa acuminata	31.94	4.00e-44	169.00
IUUC-Mpu-066389	Mustela putorius furo	45.19	3.00e-15	73.90
IUUC-Mlu-067999	Myotis lucifugus	40.80	1.00e-26	112.00
IUUC-Nfi-068390	Neosartorya fischeri	43.82	4.00e-57	213.00
IUUC-Ncr-068685	Neurospora crassa	41.75	2.00e-58	217.00
IUUC-Nle-069655	Nomascus leucogenys	39.65	1.00e-28	118.00
IUUC-Opr-070234	Ochotona princeps	46.43	6.00e-10	56.20
IUUC-Ont-072484	Oreochromis niloticus	34.59	5.00e-44	169.00
IUUC-Oan-073572	Ornithorhynchus anatinus	34.77	8.00e-41	158.00
IUUC-Ocu-074831	Oryctolagus cuniculus	40.96	2.00e-25	108.00
IUUC-Oba-075392	Oryza barthii	35.74	3.00e-34	137.00
IUUC-Obr-076660	Oryza brachyantha	32.90	2.00e-41	160.00
IUUC-Ogl-077152	Oryza glaberrima	32.93	1.00e-39	154.00
IUUC-Ogu-078883	Oryza glumaepatula	35.74	3.00e-34	137.00
IUUC-Oin-079817	Oryza indica	34.94	8.00e-33	132.00
IUUC-Olo-080929	Oryza longistaminata	35.34	8.00e-34	135.00
IUUC-Ome-081866	Oryza meridionalis	35.74	2.00e-34	137.00
IUUC-Oni-083092	Oryza nivara	34.94	8.00e-33	132.00
IUUC-Opu-083756	Oryza punctata	35.71	5.00e-35	139.00
IUUC-Oru-084816	Oryza rufipogon	34.94	8.00e-33	132.00
IUUC-Osa-086112	Oryza sativa	34.94	8.00e-33	132.00
IUUC-Ola-086540	Oryzias latipes	35.61	1.00e-27	115.00
IUUC-Olu-087843	Ostreococcus lucimarinus	33.07	2.00e-38	150.00
IUUC-Oga-088023	Otolemur garnettii	40.24	4.00e-27	113.00
IUUC-Oar-089964	Ovis aries	43.21	1.00e-27	115.00
IUUC-Ptr-091165	Pan troglodytes	39.03	3.00e-27	114.00
IUUC-Pan-092009	Papio anubis	39.24	5.00e-27	113.00
IUUC-Psi-093477	Pelodiscus sinensis	44.90	2.00e-12	64.70
IUUC-Pno-095064	Phaeosphaeria nodorum	43.72	8.00e-45	172.00
IUUC-Ppa-095654	Physcomitrella patens	41.13	5.00e-39	152.00
IUUC-Pfo-096607	Poecilia formosa	35.37	2.00e-41	160.00
IUUC-Pab-097868	Pongo abelii	39.92	4.00e-27	113.00
IUUC-Pop-099642	Populus trichocarpa	32.85	1.00e-44	172.00
IUUC-Pca-100348	Procavia capensis	39.51	5.00e-33	133.00
IUUC-Ppe-101185	Prunus persica	30.89	4.00e-39	153.00
IUUC-Pva-102137	Pteropus vampyrus	41.53	2.00e-27	114.00
IUUC-Pgr-103641	Puccinia graminis	35.34	3.00e-29	120.00
IUUC-Ptt-103717	Puccinia triticina	50.78	3.00e-32	130.00
IUUC-Pte-104303	Pyrenophora teres	45.22	1.00e-54	204.00
IUUC-Pyt-104580	Pyrenophora triticirepentis	44.19	2.00e-54	204.00
IUUC-Rno-105569	Rattus norvegicus	39.67	3.00e-33	134.00
IUUC-Sce-106214	Saccharomyces cerevisiae	35.29	2.00e-18	84.70
IUUC-Sha-107073	Sarcophilus harrisii	45.26	2.00e-15	74.70
IUUC-Sja-107851	Schizosaccharomyces japonicus	59.36	8.00e-107	378.00
IUUC-Ssl-108382	Sclerotinia sclerotiorum	42.86	4.00e-33	133.00
IUUC-Smo-109518	Selaginella moellendorffii	46.81	2.00e-21	94.70
IUUC-Sit-109813	Setaria italica	33.16	6.00e-39	152.00
IUUC-Sly-111349	Solanum lycopersicum	35.58	2.00e-45	174.00
IUUC-Stu-112306	Solanum tuberosum	34.64	6.00e-42	162.00
IUUC-Sar-112925	Sorex araneus	41.05	9.00e-26	108.00
IUUC-Sbi-114459	Sorghum bicolor	33.68	2.00e-41	160.00
IUUC-Sre-114894	Sporisorium reilianum	72.09	2.00e-15	75.10
IUUC-Ssc-116329	Sus scrofa	41.53	2.00e-27	114.00
IUUC-Tgu-116918	Taeniopygia guttata	39.92	4.00e-28	116.00
IUUC-Tru-117920	Takifugu rubripes	37.45	1.00e-39	154.00
IUUC-Tsy-118836	Tarsius syrichta	41.51	6.00e-15	73.20
IUUC-Tni-120493	Tetraodon nigroviridis	35.52	1.00e-47	181.00
IUUC-Tca-121661	Theobroma cacao	32.74	1.00e-42	165.00
IUUC-Tre-121911	Trichoderma reesei	42.18	2.00e-52	197.00
IUUC-Tvi-122617	Trichoderma virens	45.26	4.00e-66	243.00
IUUC-Tae-125620	Triticum aestivum	34.11	6.00e-39	152.00
IUUC-Tur-126101	Triticum urartu	32.29	1.00e-32	132.00
IUUC-Tme-127092	Tuber melanosporum	46.08	2.00e-67	247.00
IUUC-Tbe-127493	Tupaia belangeri	46.97	2.00e-15	75.10
IUUC-Ttr-128464	Tursiops truncatus	42.15	2.00e-27	114.00
IUUC-Uma-129484	Ustilago maydis	61.11	2.00e-16	77.80
IUUC-Vda-129946	Verticillium dahliae	43.75	1.00e-30	125.00
IUUC-Vpa-130357	Vicugna pacos	47.83	2.00e-12	64.30
IUUC-Vvi-131039	Vitis vinifera	38.80	1.00e-38	151.00
IUUC-Xtr-132679	Xenopus tropicalis	45.57	1.00e-14	72.00
IUUC-Xma-133503	Xiphophorus maculatus	37.80	6.00e-37	145.00
IUUC-Yli-134615	Yarrowia lipolytica	37.34	4.00e-52	196.00
IUUC-Zma-135929	Zea mays	33.83	3.00e-43	166.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence