iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010810

Ensembl Protein ID

ENSAMXP00000008462.1

UniProt Accession

W5KLK0; W5KLK0_ASTMX

Genbank Protein ID

ENSAMXP00000008462

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01079330

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000008170.1	ENSAMXT00000008462.1	ENSAMXP00000008462.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.40e-134	446.8	618	949

Active Site

Position(s)	Description	Evidence
919	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++ lk+rl++ef+ E+gld+gGv+re+++llske++np++glf+ys++d++tlq+np+sgl+n++hl++F+f+Gr+ g+a+++g+lld 
   Q: 618  PDVLKARLWIEFESEKGLDYGGVAREWFFLLSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDG 706
           57899************************************************************************************ PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
           ++ ++fyk++lgk++sl+d+e+vd+e+y+slk+i+en     + ++ldl+f+++e+++g+t++++Lkp+G+++ Vtn+Nk+eY++lv++
   Q: 707  FFIRPFYKMMLGKQISLNDMESVDSEYYNSLKWILEN-----DPMDLDLRFCIDEDNFGQTYQVDLKPSGSDMVVTNDNKKEYIDLVIQ 790
           ***********************************99.....56779****************************************** PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +++++q++af eGf+e+i ++l+++F+e+elell+cG  ++dv+d++++t yk+gy +++p+iqwFw+++  +++e+r ++LqFv
   Q: 791  WRFVNRVQKQMNAFMEGFTELILIDLIKIFDENELELLMCGLGDVDVNDWRQHTVYKNGYCPNHPVIQWFWKAVLLMDAEKRIRLLQFV 879
           ***************************************************************************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           Tg+sr+P++Gfael     p+lf+i++++++d+lP+++TCfn+L+LP Y+s + l+ekLl+A+e+++gFe
   Q: 880  TGTSRVPMNGFAELYgsngPQLFTIEQWGTPDKLPRAHTCFNRLDLPSYESFDDLREKLLMAVENAQGFE 949
           *********************************************************************8 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

SDPYVKLSLY VADENRELAL VQTKTIKKTL NPKWNEEFYF RVCPQNHRLL FEVFDENRLT 60
RDDFLGQVDV PLNHLPTEDP AMERPYTFKD FLLRPRSHKS RVKGYLRLKM AYLPKNGAQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTGATCCCT ACGTCAAACT GTCCCTGTAC GTCGCTGACG AGAACCGCGA GCTTGCCTTA 60
GTCCAGACTA AAACCATCAA AAAGGTACAA ATTTTACGTT TCTTTATTAA GTTTGTAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003893	Anas platyrhynchos	72.19	0.00e+00	1303.00
IUUC-Aca-004744	Anolis carolinensis	69.61	0.00e+00	1243.00
IUUC-Ago-007742	Ashbya gossypii	48.10	6.00e-162	564.00
IUUC-Acl-008273	Aspergillus clavatus	46.81	2.00e-158	553.00
IUUC-Afl-008713	Aspergillus flavus	44.73	8.00e-160	557.00
IUUC-Afu-009103	Aspergillus fumigatus	47.28	2.00e-159	556.00
IUUC-Ani-009259	Aspergillus nidulans	48.11	7.00e-159	554.00
IUUC-Ang-009738	Aspergillus niger	48.86	5.00e-159	555.00
IUUC-Aor-010053	Aspergillus oryzae	57.72	2.00e-100	358.00
IUUC-Ate-010529	Aspergillus terreus	48.60	6.00e-160	558.00
IUUC-Bgr-012148	Blumeria graminis	47.13	6.00e-153	534.00
IUUC-Bta-012679	Bos taurus	69.96	0.00e+00	1185.00
IUUC-Bci-013785	Botrytis cinerea	46.88	2.00e-153	536.00
IUUC-Cja-018732	Callithrix jacchus	71.74	0.00e+00	1306.00
IUUC-Cfa-021226	Canis familiaris	71.98	0.00e+00	1312.00
IUUC-Cpo-021671	Cavia porcellus	70.89	0.00e+00	1289.00
IUUC-Csa-023344	Chlorocebus sabaeus	70.19	0.00e+00	1288.00
IUUC-Cho-024832	Choloepus hoffmanni	93.47	0.00e+00	709.00
IUUC-Dre-027770	Danio rerio	91.68	0.00e+00	1095.00
IUUC-Dno-029466	Dasypus novemcinctus	72.40	0.00e+00	1317.00
IUUC-Dor-030138	Dipodomys ordii	68.36	0.00e+00	1229.00
IUUC-Ete-033145	Echinops telfairi	78.14	0.00e+00	996.00
IUUC-Eca-033445	Equus caballus	70.14	0.00e+00	1186.00
IUUC-Eeu-035247	Erinaceus europaeus	84.28	0.00e+00	1063.00
IUUC-Fca-035489	Felis catus	67.84	0.00e+00	1136.00
IUUC-Fal-037604	Ficedula albicollis	71.71	0.00e+00	1301.00
IUUC-Fso-038393	Fusarium solani	45.65	6.00e-151	528.00
IUUC-Gmo-039674	Gadus morhua	86.91	0.00e+00	1058.00
IUUC-Ggr-040107	Gaeumannomyces graminis	46.96	9.00e-153	534.00
IUUC-Gga-040703	Gallus gallus	72.50	0.00e+00	1312.00
IUUC-Gac-042020	Gasterosteus aculeatus	90.65	0.00e+00	1095.00
IUUC-Ggo-045332	Gorilla gorilla	70.66	0.00e+00	1281.00
IUUC-Hsa-045968	Homo sapiens	71.50	0.00e+00	1300.00
IUUC-Lch-050443	Latimeria chalumnae	70.76	0.00e+00	1160.00
IUUC-Loc-052662	Lepisosteus oculatus	89.48	0.00e+00	1071.00
IUUC-Laf-053850	Loxodonta africana	70.69	0.00e+00	1290.00
IUUC-Mcc-055821	Macaca mulatta	71.61	0.00e+00	1299.00
IUUC-Mor-057097	Magnaporthe oryzae	45.23	1.00e-154	540.00
IUUC-Mpo-057442	Magnaporthe poae	51.23	1.00e-143	504.00
IUUC-Mla-058996	Melampsora laricipopulina	46.64	2.00e-153	536.00
IUUC-Mvi-060395	Microbotryum violaceum	54.45	2.00e-151	530.00
IUUC-Mmr-060798	Microcebus murinus	68.08	0.00e+00	1207.00
IUUC-Mdo-062173	Monodelphis domestica	70.22	0.00e+00	1301.00
IUUC-Mmu-064136	Mus musculus	71.88	0.00e+00	1309.00
IUUC-Mpu-066765	Mustela putorius furo	71.88	0.00e+00	1302.00
IUUC-Mlu-067565	Myotis lucifugus	70.43	0.00e+00	1181.00
IUUC-Nfi-068427	Neosartorya fischeri	47.28	1.00e-159	556.00
IUUC-Ncr-068918	Neurospora crassa	45.89	1.00e-152	534.00
IUUC-Nle-069070	Nomascus leucogenys	68.53	0.00e+00	1230.00
IUUC-Opr-071044	Ochotona princeps	84.59	0.00e+00	1061.00
IUUC-Ont-072044	Oreochromis niloticus	89.25	0.00e+00	1135.00
IUUC-Oan-073032	Ornithorhynchus anatinus	66.32	0.00e+00	1053.00
IUUC-Ocu-074160	Oryctolagus cuniculus	70.61	0.00e+00	1275.00
IUUC-Ola-087467	Oryzias latipes	88.94	0.00e+00	1080.00
IUUC-Oga-088460	Otolemur garnettii	70.09	0.00e+00	1183.00
IUUC-Oar-090198	Ovis aries	71.67	0.00e+00	1295.00
IUUC-Ptr-090939	Pan troglodytes	71.50	0.00e+00	1300.00
IUUC-Pan-092284	Papio anubis	71.71	0.00e+00	1303.00
IUUC-Psi-093645	Pelodiscus sinensis	71.77	0.00e+00	1304.00
IUUC-Pma-094364	Petromyzon marinus	83.37	0.00e+00	844.00
IUUC-Pno-095118	Phaeosphaeria nodorum	47.04	5.00e-158	551.00
IUUC-Pfo-096768	Poecilia formosa	95.02	0.00e+00	986.00
IUUC-Pab-098088	Pongo abelii	71.71	0.00e+00	1300.00
IUUC-Pca-100714	Procavia capensis	77.04	0.00e+00	937.00
IUUC-Pva-102354	Pteropus vampyrus	70.82	0.00e+00	1284.00
IUUC-Pgr-103620	Puccinia graminis	53.31	4.00e-147	515.00
IUUC-Ptt-103806	Puccinia triticina	53.37	3.00e-123	435.00
IUUC-Pte-104016	Pyrenophora teres	47.13	4.00e-156	545.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	47.13	4.00e-156	545.00
IUUC-Rno-105318	Rattus norvegicus	72.08	0.00e+00	1310.00
IUUC-Sce-106289	Saccharomyces cerevisiae	48.94	7.00e-164	570.00
IUUC-Sha-107482	Sarcophilus harrisii	70.32	0.00e+00	1187.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	47.04	8.00e-155	541.00
IUUC-Ssc-115950	Sus scrofa	71.11	0.00e+00	875.00
IUUC-Tgu-117130	Taeniopygia guttata	72.50	0.00e+00	1310.00
IUUC-Tru-118610	Takifugu rubripes	90.52	0.00e+00	1122.00
IUUC-Tsy-119492	Tarsius syrichta	67.36	0.00e+00	1196.00
IUUC-Tre-122203	Trichoderma reesei	45.89	3.00e-150	525.00
IUUC-Tvi-122595	Trichoderma virens	46.38	1.00e-151	530.00
IUUC-Ttr-128235	Tursiops truncatus	88.29	0.00e+00	992.00
IUUC-Xtr-132859	Xenopus tropicalis	73.41	0.00e+00	1313.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence