iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003978

Ensembl Protein ID

ENSAPLP00000003118.1

UniProt Accession

U3I797; U3I797_ANAPL

Genbank Protein ID

ENSAPLP00000003118

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01026485

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000003622.1	ENSAPLT00000003713.1	ENSAPLP00000003118.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.80e-17	63.1	64	129
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.50e-09	34.8	163	194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e+ e k +  +ei+d + +++++l+kF+Y+++l++
   Q: 64   CDVTLKVGTKLISCHKLVLACVIPYFRAMFLSEMAEAK-QTLIEIRDFDGDAVEDLVKFVYSSRLTL 129
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+ +++ hF+
   Q: 163  PSNCLAVRAFAESHNRIDLMDMADQYACEHFT 194
           89*****************************7 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MASESLVSEQ GKQHLMKGRR RPQQQQTRSS TGDAEDDVFV FEANEAWKDF HSSLLHFFEA 60
GELCDVTLKV GTKLISCHKL VLACVIPYFR AMFLSEMAEA KQTLIEIRDF DGDAVEDLVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCAG AATCCTTGGT CTCCGAGCAG GGAAAGCAAC ATCTGATGAA GGGAAGAAGG 60
AGGCCACAGC AGCAGCAAAC GAGATCTTCC ACTGGTGATG CTGAAGATGA CGTCTTCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

apla:101793817

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	89.84	0.00e+00	1143.00
IUUC-Atr-002726	Amborella trichopoda	36.63	3.00e-43	169.00
IUUC-Aca-004958	Anolis carolinensis	87.06	0.00e+00	1103.00
IUUC-Ame-011139	Astyanax mexicanus	82.20	0.00e+00	1071.00
IUUC-Bta-013142	Bos taurus	89.48	0.00e+00	1138.00
IUUC-Bdi-014143	Brachypodium distachyon	38.30	1.00e-42	167.00
IUUC-Cel-018551	Caenorhabditis elegans	39.90	2.00e-128	452.00
IUUC-Cja-019650	Callithrix jacchus	89.37	0.00e+00	1161.00
IUUC-Cfa-021046	Canis familiaris	90.29	0.00e+00	1146.00
IUUC-Cpo-022445	Cavia porcellus	88.37	0.00e+00	1100.00
IUUC-Csa-023642	Chlorocebus sabaeus	89.53	0.00e+00	1164.00
IUUC-Cho-025012	Choloepus hoffmanni	75.39	0.00e+00	854.00
IUUC-Dre-027723	Danio rerio	80.88	0.00e+00	1052.00
IUUC-Dno-028964	Dasypus novemcinctus	90.41	0.00e+00	959.00
IUUC-Dor-030899	Dipodomys ordii	78.48	2.00e-130	459.00
IUUC-Ete-032815	Echinops telfairi	87.88	0.00e+00	1128.00
IUUC-Eca-034162	Equus caballus	90.15	0.00e+00	1138.00
IUUC-Eeu-034660	Erinaceus europaeus	89.48	0.00e+00	1137.00
IUUC-Fca-035659	Felis catus	90.16	0.00e+00	1145.00
IUUC-Fal-037619	Ficedula albicollis	93.84	0.00e+00	1204.00
IUUC-Fox-037999	Fusarium oxysporum	28.00	5.00e-08	50.80
IUUC-Gmo-038546	Gadus morhua	84.71	0.00e+00	1051.00
IUUC-Ggr-040041	Gaeumannomyces graminis	32.65	2.00e-08	53.50
IUUC-Gga-040770	Gallus gallus	96.43	0.00e+00	1203.00
IUUC-Gac-042557	Gasterosteus aculeatus	79.13	0.00e+00	1036.00
IUUC-Ggo-044741	Gorilla gorilla	89.53	0.00e+00	1164.00
IUUC-Hsa-046025	Homo sapiens	89.53	0.00e+00	1164.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	93.44	0.00e+00	1067.00
IUUC-Loc-052834	Lepisosteus oculatus	86.34	0.00e+00	1013.00
IUUC-Laf-054513	Loxodonta africana	89.34	0.00e+00	1149.00
IUUC-Mcc-054707	Macaca mulatta	89.37	0.00e+00	1160.00
IUUC-Meu-056779	Macropus eugenii	90.03	0.00e+00	1164.00
IUUC-Mtr-058180	Medicago truncatula	32.95	1.00e-35	144.00
IUUC-Mga-059676	Meleagris gallopavo	96.76	0.00e+00	1205.00
IUUC-Mmr-061359	Microcebus murinus	88.71	0.00e+00	1123.00
IUUC-Mdo-062527	Monodelphis domestica	88.44	0.00e+00	1149.00
IUUC-Mmu-063112	Mus musculus	87.12	0.00e+00	1141.00
IUUC-Mac-064682	Musa acuminata	35.47	7.00e-42	165.00
IUUC-Mpu-065800	Mustela putorius furo	89.35	0.00e+00	1137.00
IUUC-Mlu-067536	Myotis lucifugus	87.79	0.00e+00	1095.00
IUUC-Nle-069397	Nomascus leucogenys	89.37	0.00e+00	1161.00
IUUC-Opr-070599	Ochotona princeps	89.43	0.00e+00	946.00
IUUC-Ont-072580	Oreochromis niloticus	84.02	0.00e+00	1051.00
IUUC-Oan-073180	Ornithorhynchus anatinus	90.95	0.00e+00	1169.00
IUUC-Ocu-074026	Oryctolagus cuniculus	89.82	0.00e+00	1133.00
IUUC-Ola-086776	Oryzias latipes	83.16	0.00e+00	1006.00
IUUC-Oga-088651	Otolemur garnettii	89.53	0.00e+00	1140.00
IUUC-Oar-089567	Ovis aries	88.67	0.00e+00	1113.00
IUUC-Ptr-091564	Pan troglodytes	89.53	0.00e+00	1164.00
IUUC-Pan-092578	Papio anubis	89.53	0.00e+00	1164.00
IUUC-Psi-093635	Pelodiscus sinensis	90.07	0.00e+00	1102.00
IUUC-Pma-094660	Petromyzon marinus	61.64	0.00e+00	758.00
IUUC-Pfo-097507	Poecilia formosa	79.93	0.00e+00	979.00
IUUC-Pab-098025	Pongo abelii	89.53	0.00e+00	1164.00
IUUC-Pca-101046	Procavia capensis	82.74	2.00e-175	608.00
IUUC-Ppe-101154	Prunus persica	32.68	2.00e-38	153.00
IUUC-Pva-102359	Pteropus vampyrus	93.41	0.00e+00	875.00
IUUC-Rno-105750	Rattus norvegicus	87.76	0.00e+00	1132.00
IUUC-Sha-107513	Sarcophilus harrisii	90.82	0.00e+00	1169.00
IUUC-Sly-111482	Solanum lycopersicum	32.68	6.00e-42	165.00
IUUC-Stu-112032	Solanum tuberosum	33.07	1.00e-42	167.00
IUUC-Sar-113616	Sorex araneus	68.49	2.00e-114	405.00
IUUC-Ssc-116205	Sus scrofa	89.67	0.00e+00	954.00
IUUC-Tgu-117435	Taeniopygia guttata	94.00	0.00e+00	1203.00
IUUC-Tru-118709	Takifugu rubripes	83.33	0.00e+00	1049.00
IUUC-Tsy-119466	Tarsius syrichta	93.80	0.00e+00	1071.00
IUUC-Tni-119988	Tetraodon nigroviridis	83.36	0.00e+00	1045.00
IUUC-Tae-124075	Triticum aestivum	36.13	4.00e-39	155.00
IUUC-Tbe-127704	Tupaia belangeri	91.61	0.00e+00	1025.00
IUUC-Ttr-128892	Tursiops truncatus	92.66	0.00e+00	888.00
IUUC-Vpa-130545	Vicugna pacos	90.04	0.00e+00	959.00
IUUC-Xtr-132289	Xenopus tropicalis	84.11	0.00e+00	1029.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence