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Tag Content
iUUCD ID IUUC-Cfa-020020
Ensembl Protein ID ENSCAFP00000010253.3
UniProt Accession F1PTZ8; F1PTZ8_CANLF
Genbank Protein ID ENSCAFP00000010253
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AAEX03001009
Gene Name KMT2B
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000006878.4 ENSCAFT00000046023.2 ENSCAFP00000038522.1
ENSCAFG00000006878.4 ENSCAFT00000011064.3 ENSCAFP00000010253.3
ENSCAFG00000006878.4 ENSCAFT00000011116.3 ENSCAFP00000010297.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 9.80e-30 102.8 1262 1315
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           k+C+vCg++g+++k+l+eCe+Cr+++HpaCl++s ++++ ++++  wiC+ C ++
   Q: 1262 KFCHVCGRKGRGSKHLLECERCRHAYHPACLGPS-YPTRATRKRrhWICSACVRC 1315
           58********************************.88888877777******876 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
LTQASDGDAL PSPHSARGRF PGRPRGSAGG GGRGGRGSGA ERVRVALRRG GGAAGPGGAE 60
PGEDTALLRL LGLRRGLRRL RRLWAGPRIQ RGRGRGRGRG WGPSRGCVPE EESSDEESDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020020|E3,PHD|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTAGCGGCGA CAGCGACGGC TGCAGCGATG GCCGGGGCGG GGCCAGCCCC GGGACTCCCG 60
GGTGCAGGAG GACCTGTGGT CCCGGGCGCC GGCATGCCGG GCAAGAGCGG GGAGGAACGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020020|E3,PHD|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC
SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0016458--P:gene silencing
GO:0080182--P:histone H3-K4 trimethylation
GO:0007613--P:memory
GO:0009994--P:oocyte differentiation
GO:0001541--P:ovarian follicle development
GO:0030728--P:ovulation
GO:0051569--P:regulation of histone H3-K4 methylation
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002367 Ailuropoda melanoleuca 97.21 0.00e+00 3323.00
IUUC-Aca-004718 Anolis carolinensis 58.16 0.00e+00 1971.00
IUUC-Ame-011927 Astyanax mexicanus 44.06 0.00e+00 851.00
IUUC-Bta-013578 Bos taurus 96.35 0.00e+00 2999.00
IUUC-Bdi-014882 Brachypodium distachyon 32.84 5.00e-27 116.00
IUUC-Bra-017422 Brassica rapa 33.01 3.00e-27 117.00
IUUC-Cja-019138 Callithrix jacchus 90.09 0.00e+00 3219.00
IUUC-Cpo-021552 Cavia porcellus 89.83 0.00e+00 3162.00
IUUC-Csa-024216 Chlorocebus sabaeus 92.79 0.00e+00 3232.00
IUUC-Cho-024565 Choloepus hoffmanni 76.94 1.00e-166 581.00
IUUC-Dre-027440 Danio rerio 44.58 0.00e+00 907.00
IUUC-Dno-029583 Dasypus novemcinctus 92.41 0.00e+00 3218.00
IUUC-Dor-030903 Dipodomys ordii 88.10 0.00e+00 2171.00
IUUC-Dme-032023 Drosophila melanogaster 47.28 2.00e-92 336.00
IUUC-Eca-034026 Equus caballus 96.94 0.00e+00 1934.00
IUUC-Eeu-034687 Erinaceus europaeus 94.29 0.00e+00 1146.00
IUUC-Fca-036311 Felis catus 96.33 0.00e+00 3353.00
IUUC-Gmo-039265 Gadus morhua 45.11 0.00e+00 811.00
IUUC-Gac-042202 Gasterosteus aculeatus 48.02 0.00e+00 739.00
IUUC-Ggo-044791 Gorilla gorilla 94.26 0.00e+00 2100.00
IUUC-Hsa-046988 Homo sapiens 92.39 0.00e+00 3140.00
IUUC-Hvu-047762 Hordeum vulgare 35.82 8.00e-20 92.00
IUUC-Itr-048907 Ictidomys tridecemlineatus 91.81 0.00e+00 3315.00
IUUC-Lpe-051476 Leersia perrieri 31.05 1.00e-23 105.00
IUUC-Loc-052252 Lepisosteus oculatus 53.88 0.00e+00 783.00
IUUC-Laf-053703 Loxodonta africana 94.12 0.00e+00 2177.00
IUUC-Mcc-054782 Macaca mulatta 91.32 0.00e+00 2458.00
IUUC-Meu-056046 Macropus eugenii 87.34 0.00e+00 1727.00
IUUC-Mmr-061316 Microcebus murinus 89.30 0.00e+00 3006.00
IUUC-Mdo-062648 Monodelphis domestica 79.73 0.00e+00 2006.00
IUUC-Mmu-063579 Mus musculus 89.40 0.00e+00 3225.00
IUUC-Mac-064935 Musa acuminata 32.87 2.00e-29 124.00
IUUC-Mpu-066710 Mustela putorius furo 97.83 0.00e+00 3335.00
IUUC-Mlu-067559 Myotis lucifugus 91.53 0.00e+00 3253.00
IUUC-Nle-070085 Nomascus leucogenys 89.62 0.00e+00 2155.00
IUUC-Opr-071148 Ochotona princeps 88.68 0.00e+00 3160.00
IUUC-Ont-071626 Oreochromis niloticus 44.59 0.00e+00 889.00
IUUC-Ocu-074475 Oryctolagus cuniculus 89.94 0.00e+00 3147.00
IUUC-Obr-076458 Oryza brachyantha 33.99 1.00e-27 118.00
IUUC-Ogl-077851 Oryza glaberrima 35.71 9.00e-28 118.00
IUUC-Ogu-078706 Oryza glumaepatula 35.71 6.00e-28 119.00
IUUC-Oin-079802 Oryza indica 30.95 8.00e-23 102.00
IUUC-Osa-085421 Oryza sativa 35.71 1.00e-27 118.00
IUUC-Ola-086609 Oryzias latipes 51.61 0.00e+00 753.00
IUUC-Oga-088140 Otolemur garnettii 92.75 0.00e+00 3220.00
IUUC-Oar-089447 Ovis aries 94.98 0.00e+00 2073.00
IUUC-Ptr-090902 Pan troglodytes 92.30 0.00e+00 3155.00
IUUC-Pan-091930 Papio anubis 92.75 0.00e+00 3239.00
IUUC-Ppa-095221 Physcomitrella patens 35.55 2.00e-30 127.00
IUUC-Pfo-096884 Poecilia formosa 45.19 0.00e+00 877.00
IUUC-Pab-098404 Pongo abelii 83.39 0.00e+00 2369.00
IUUC-Pop-099620 Populus trichocarpa 31.37 4.00e-26 113.00
IUUC-Pca-100949 Procavia capensis 84.04 0.00e+00 1264.00
IUUC-Ppe-101920 Prunus persica 32.06 2.00e-27 117.00
IUUC-Pva-102634 Pteropus vampyrus 93.89 0.00e+00 3318.00
IUUC-Rno-105870 Rattus norvegicus 88.80 0.00e+00 3301.00
IUUC-Sit-110552 Setaria italica 33.83 2.00e-28 120.00
IUUC-Sar-113289 Sorex araneus 90.46 0.00e+00 1750.00
IUUC-Ssc-115509 Sus scrofa 94.16 0.00e+00 3292.00
IUUC-Tru-117736 Takifugu rubripes 45.37 0.00e+00 835.00
IUUC-Tca-121624 Theobroma cacao 31.71 2.00e-27 117.00
IUUC-Tae-124647 Triticum aestivum 35.82 7.00e-20 92.00
IUUC-Tbe-127825 Tupaia belangeri 89.53 0.00e+00 1458.00
IUUC-Ttr-128754 Tursiops truncatus 95.09 0.00e+00 1258.00
IUUC-Xtr-132838 Xenopus tropicalis 48.79 0.00e+00 985.00
IUUC-Xma-133119 Xiphophorus maculatus 42.95 0.00e+00 954.00
Created Date 25-Jun-2017

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