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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046190
UUCD1 version UUC-HoS-00983
Ensembl Protein ID ENSP00000436713.1
UniProt Accession A0A075B6T4; A0A075B6T4_HUMAN
Genbank Protein ID ENSP00000436713
Protein Name Kelch repeat and BTB domain-containing protein 4
Genbank Nucleotide ID AC104942
Gene Name KBTBD4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000123444.13 ENST00000533290.5 ENSP00000436713.1
ENSG00000123444.13 ENST00000430070.6 ENSP00000415106.2
ENSG00000123444.13 ENST00000525720.1 ENSP00000434477.1
ENSG00000123444.13 ENST00000530668.1 ENSP00000435850.1
ENSG00000123444.13 ENST00000529499.1 ENSP00000433404.1
ENSG00000123444.13 ENST00000534239.1 ENSP00000433124.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACRepTar
miRcodeRAID2
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 5.50e-17 63.6 70 135
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           aDv++ v+g+ef+ h++vL+a+S +F+++f+++l+e + +  ++++dv+ +vf+ l++++Y+g++++
   Q: 70   ADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKEAH-NRVIVLQDVSESVFQLLVDYIYHGTVKL 135
           7************************************8.8888889*****************9976 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MAVNSSGYSR WCCFADSWQR EKLASMESPE EPGASMDENY FVNYTFKDRS HSGRVAQGIM 60
KLCLEEELFA DVTISVEGRE FQLHRLVLSA QSCFFRSMFT SNLKEAHNRV IVLQDVSESV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046190|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAGTGTGCAG CAGATCTTCT TCCGGGCGGA CGTGGAGCCG GAAGCGGAGG TTCCGGGCTC 60
CGGGATGAAA GGAGGGAACG CAGGTGAGAA AGCGAGACAG GCAGGTAGGG AAATCGTGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046190|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
SMART

SM00875--BACK
SM00225--BTB
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002204 Ailuropoda melanoleuca 98.51 0.00e+00 1103.00
IUUC-Apl-003672 Anas platyrhynchos 88.27 0.00e+00 981.00
IUUC-Aca-005260 Anolis carolinensis 89.31 0.00e+00 956.00
IUUC-Acl-008230 Aspergillus clavatus 24.62 1.00e-09 57.00
IUUC-Afu-008999 Aspergillus fumigatus 23.45 3.00e-05 42.40
IUUC-Ame-010776 Astyanax mexicanus 77.32 0.00e+00 835.00
IUUC-Bta-012565 Bos taurus 98.68 0.00e+00 1087.00
IUUC-Bci-013980 Botrytis cinerea 23.50 2.00e-05 43.10
IUUC-Cja-019354 Callithrix jacchus 99.63 0.00e+00 1130.00
IUUC-Cfa-021177 Canis familiaris 99.05 0.00e+00 1095.00
IUUC-Cpo-021789 Cavia porcellus 97.51 0.00e+00 1068.00
IUUC-Csa-023309 Chlorocebus sabaeus 99.62 0.00e+00 1099.00
IUUC-Cho-024678 Choloepus hoffmanni 96.14 0.00e+00 1035.00
IUUC-Dre-027414 Danio rerio 76.05 0.00e+00 829.00
IUUC-Dno-029471 Dasypus novemcinctus 98.30 0.00e+00 1089.00
IUUC-Dor-030252 Dipodomys ordii 96.77 9.00e-124 437.00
IUUC-Ete-033084 Echinops telfairi 95.15 1.00e-131 463.00
IUUC-Eca-033967 Equus caballus 97.79 0.00e+00 1113.00
IUUC-Eeu-035043 Erinaceus europaeus 98.65 0.00e+00 1064.00
IUUC-Fca-035517 Felis catus 99.05 0.00e+00 1095.00
IUUC-Fal-037254 Ficedula albicollis 91.49 0.00e+00 978.00
IUUC-Fso-038419 Fusarium solani 41.18 9.00e-07 47.80
IUUC-Gmo-038977 Gadus morhua 78.61 0.00e+00 842.00
IUUC-Ggr-039934 Gaeumannomyces graminis 31.33 1.00e-07 51.20
IUUC-Gga-040324 Gallus gallus 88.87 0.00e+00 977.00
IUUC-Gac-042283 Gasterosteus aculeatus 74.50 0.00e+00 832.00
IUUC-Ggo-044642 Gorilla gorilla 99.81 0.00e+00 1102.00
IUUC-Itr-048161 Ictidomys tridecemlineatus 99.06 0.00e+00 1100.00
IUUC-Lch-050111 Latimeria chalumnae 81.39 0.00e+00 915.00
IUUC-Loc-051966 Lepisosteus oculatus 78.24 0.00e+00 860.00
IUUC-Laf-053441 Loxodonta africana 98.30 0.00e+00 1086.00
IUUC-Mcc-055792 Macaca mulatta 99.62 0.00e+00 1099.00
IUUC-Mor-057055 Magnaporthe oryzae 40.26 8.00e-12 64.30
IUUC-Mga-059748 Meleagris gallopavo 88.89 0.00e+00 980.00
IUUC-Mmr-060983 Microcebus murinus 99.25 0.00e+00 1108.00
IUUC-Mdo-062425 Monodelphis domestica 90.06 0.00e+00 935.00
IUUC-Mmu-063983 Mus musculus 99.06 0.00e+00 1098.00
IUUC-Mpu-066607 Mustela putorius furo 99.23 0.00e+00 1077.00
IUUC-Mlu-068099 Myotis lucifugus 95.28 0.00e+00 1061.00
IUUC-Nle-069560 Nomascus leucogenys 99.62 0.00e+00 1099.00
IUUC-Opr-071169 Ochotona princeps 98.07 0.00e+00 1065.00
IUUC-Ont-071876 Oreochromis niloticus 79.21 0.00e+00 835.00
IUUC-Oan-072875 Ornithorhynchus anatinus 90.94 0.00e+00 979.00
IUUC-Ocu-074904 Oryctolagus cuniculus 98.68 0.00e+00 1092.00
IUUC-Ola-087067 Oryzias latipes 76.95 0.00e+00 845.00
IUUC-Oga-088606 Otolemur garnettii 97.79 0.00e+00 1115.00
IUUC-Oar-090448 Ovis aries 98.68 0.00e+00 1089.00
IUUC-Ptr-090478 Pan troglodytes 99.62 0.00e+00 1100.00
IUUC-Pan-092040 Papio anubis 99.26 0.00e+00 1127.00
IUUC-Psi-093737 Pelodiscus sinensis 91.29 0.00e+00 975.00
IUUC-Pno-095090 Phaeosphaeria nodorum 24.75 6.00e-06 43.90
IUUC-Pfo-096505 Poecilia formosa 78.42 0.00e+00 828.00
IUUC-Pab-097553 Pongo abelii 99.57 0.00e+00 963.00
IUUC-Pca-100711 Procavia capensis 97.30 0.00e+00 1047.00
IUUC-Pva-102729 Pteropus vampyrus 97.68 0.00e+00 1013.00
IUUC-Pte-104282 Pyrenophora teres 28.70 1.00e-07 49.70
IUUC-Rno-105585 Rattus norvegicus 99.23 0.00e+00 1074.00
IUUC-Sar-113597 Sorex araneus 96.80 0.00e+00 883.00
IUUC-Ssc-116251 Sus scrofa 99.03 0.00e+00 1073.00
IUUC-Tgu-116762 Taeniopygia guttata 83.62 0.00e+00 874.00
IUUC-Tru-118434 Takifugu rubripes 78.10 0.00e+00 848.00
IUUC-Tni-120126 Tetraodon nigroviridis 77.71 0.00e+00 846.00
IUUC-Ttr-128803 Tursiops truncatus 96.71 6.00e-138 484.00
IUUC-Uma-129411 Ustilago maydis 42.55 6.80e-02 33.90
IUUC-Xtr-132273 Xenopus tropicalis 81.77 0.00e+00 908.00
IUUC-Xma-133561 Xiphophorus maculatus 78.61 0.00e+00 830.00
IUUC-Yli-134483 Yarrowia lipolytica 26.09 1.00e-05 44.30
Created Date 25-Jun-2017

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