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Tag Content
UUCD2 ID IUUC-Ptr-090696
UUCD1 version UUC-PaT-01085
Ensembl Protein ID ENSPTRP00000012224.5
UniProt Accession H2Q9K0; H2Q9K0_PANTR
Genbank Protein ID ENSPTRP00000012224
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AACZ03098974
Gene Name USP3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPTRG00000007149.5 ENSPTRT00000013196.5 ENSPTRP00000012224.5
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.50e-100 336.6 137 487
UBD/ZnF/ZnF_UBP 5.00e-26 90.7 8 82
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalk 78
           tGl+NlgNtC+mN++LQ+Lsni+++ ++++e             +++ + +++ +++ +l+++++k + +lw+++++a+sp++l+ +++
   Q: 137  TGLRNLGNTCFMNAILQSLSNIEQFCCYFKElpavelrngktAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVW 225
           7******************************888888777765555555555688889******************************* PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           k+ ++f+gy+qqDa+Ef+++lld+l+ el+   n    ++  +++s+ls  +++   +  +++++ +F+g l++++ cl c+++s +++
   Q: 226  KIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLS-ASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFD 313
           *****************************77444444444444444444.45688899999**************************** PP
   S: 168  pfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
           pfldlsl++p++  +k +         sl+dcL+sft  eel++ + y c kckkkq+++kk++++klP+vL+lhLkRf+++   + r+
   Q: 314  PFLDLSLDIPSQFRSKRSknqengpvcSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTA--YLRN 400
           **********77655555678899999****************************************************7755..799* PP
   S: 248  kinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlf 334
           k++++vefpl+ Ld++ ++ +pe++  e++ Y+L avvvH+G +++sGHY+ay+ + +g+W++f+Ds+Vt ++ee+v++   ++aY+lf
   Q: 401  KVDTYVEFPLRgLDMKCYLLEPENSGPESCLYDLAAVVVHHGsGVGSGHYTAYATH-EGRWFHFNDSTVTLTDEETVVK---AKAYILF 485
           ********************************************************.9*********************...******* PP
   S: 335  Yk 336
           Y 
   Q: 486  YV 487
           *6 PP
   

   UBD/ZnF/ZnF_UBP
   S: 4    svcdktenlWlcLtcgsvgCGRyvegHalkHyeetqhpl................vlslstlsvycYacddyvhr 62
           +vc++++++W+cLtc+sv+CGRyv+gHa+kHye++q+pl                ++++s++s+ycY+cdd+v++
   Q: 8    AVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQVPLtnhkksekqdkaqhtvCMDCSSYSTYCYRCDDFVVN 82
           58***********************************************************************85 PP
   
Organism Pan troglodytes
Protein Sequence
(Fasta)
MQSPLHLAVC RSNKSPWVCL TCSSVHCGRY VNGHAKKHYE DAQVPLTNHK KSEKQDKAQH 60
TVCMDCSSYS TYCYRCDDFV VNDTKLGLVQ KVREHLQNLE NSAFTADRHR KRKLLENSTL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ptr-090696|DUB,USP;UBD,ZnF_UBP|Pan troglodytes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGCAATCAC CACTACACTT GGCAGGTAGT AAAGTGGTTT TTTTTTTTTT TTTTTTTGGA 60
GATATATTAA AAGGCACAGT CCACAGTCAC TTGTTTCCAA TGATTTTGGA AGTCAGTACT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ptr-090696|DUB,USP;UBD,ZnF_UBP|Pan troglodytes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0070938--C:contractile ring
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0016578--P:histone deubiquitination
GO:0000278--P:mitotic cell cycle
GO:0031647--P:regulation of protein stability
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG ptr:453499
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001537 Ailuropoda melanoleuca 97.76 0.00e+00 894.00
IUUC-Apl-003358 Anas platyrhynchos 94.94 0.00e+00 903.00
IUUC-Aca-004454 Anolis carolinensis 92.55 0.00e+00 809.00
IUUC-Ame-011544 Astyanax mexicanus 76.84 0.00e+00 690.00
IUUC-Bta-012738 Bos taurus 97.56 0.00e+00 879.00
IUUC-Cel-018186 Caenorhabditis elegans 37.08 2.00e-55 210.00
IUUC-Cja-018893 Callithrix jacchus 98.78 0.00e+00 894.00
IUUC-Cfa-020607 Canis familiaris 98.37 0.00e+00 880.00
IUUC-Cpo-021828 Cavia porcellus 95.93 0.00e+00 860.00
IUUC-Csa-023884 Chlorocebus sabaeus 99.76 0.00e+00 787.00
IUUC-Cho-024863 Choloepus hoffmanni 87.58 0.00e+00 754.00
IUUC-Dre-028452 Danio rerio 73.54 0.00e+00 703.00
IUUC-Dno-029531 Dasypus novemcinctus 97.36 0.00e+00 878.00
IUUC-Dor-030913 Dipodomys ordii 89.82 1.00e-178 619.00
IUUC-Ete-032611 Echinops telfairi 91.24 0.00e+00 816.00
IUUC-Eca-033622 Equus caballus 98.37 0.00e+00 883.00
IUUC-Eeu-035268 Erinaceus europaeus 92.23 0.00e+00 800.00
IUUC-Fca-035801 Felis catus 97.76 0.00e+00 910.00
IUUC-Fal-036749 Ficedula albicollis 94.50 0.00e+00 855.00
IUUC-Gmo-039598 Gadus morhua 77.75 0.00e+00 723.00
IUUC-Gga-040883 Gallus gallus 95.34 0.00e+00 870.00
IUUC-Gac-042235 Gasterosteus aculeatus 76.78 0.00e+00 701.00
IUUC-Ggo-044767 Gorilla gorilla 94.09 0.00e+00 854.00
IUUC-Hsa-046581 Homo sapiens 99.39 0.00e+00 924.00
IUUC-Itr-047898 Ictidomys tridecemlineatus 98.57 0.00e+00 884.00
IUUC-Lch-049732 Latimeria chalumnae 91.24 0.00e+00 859.00
IUUC-Loc-052371 Lepisosteus oculatus 89.21 0.00e+00 845.00
IUUC-Laf-054565 Loxodonta africana 98.17 0.00e+00 879.00
IUUC-Mcc-055522 Macaca mulatta 99.59 0.00e+00 925.00
IUUC-Meu-056754 Macropus eugenii 85.42 7.00e-159 553.00
IUUC-Mga-060095 Meleagris gallopavo 94.36 0.00e+00 641.00
IUUC-Mmr-060839 Microcebus murinus 98.37 0.00e+00 880.00
IUUC-Mdo-062339 Monodelphis domestica 97.47 0.00e+00 760.00
IUUC-Mmu-063638 Mus musculus 96.54 0.00e+00 848.00
IUUC-Mpu-066647 Mustela putorius furo 98.39 0.00e+00 764.00
IUUC-Mlu-067921 Myotis lucifugus 96.75 0.00e+00 895.00
IUUC-Nle-069752 Nomascus leucogenys 99.39 0.00e+00 922.00
IUUC-Opr-070636 Ochotona princeps 86.30 0.00e+00 731.00
IUUC-Ont-071638 Oreochromis niloticus 76.84 0.00e+00 701.00
IUUC-Oan-073417 Ornithorhynchus anatinus 90.02 0.00e+00 832.00
IUUC-Ocu-074620 Oryctolagus cuniculus 96.33 0.00e+00 868.00
IUUC-Ola-087281 Oryzias latipes 78.80 0.00e+00 629.00
IUUC-Olu-087697 Ostreococcus lucimarinus 40.59 6.00e-49 187.00
IUUC-Oga-088448 Otolemur garnettii 97.35 0.00e+00 906.00
IUUC-Oar-090132 Ovis aries 96.57 0.00e+00 879.00
IUUC-Pan-092124 Papio anubis 99.19 0.00e+00 919.00
IUUC-Psi-093801 Pelodiscus sinensis 96.55 0.00e+00 754.00
IUUC-Pma-094472 Petromyzon marinus 72.37 2.00e-95 340.00
IUUC-Pfo-096330 Poecilia formosa 78.82 0.00e+00 733.00
IUUC-Pab-098191 Pongo abelii 99.59 0.00e+00 924.00
IUUC-Pca-100341 Procavia capensis 96.36 0.00e+00 666.00
IUUC-Pva-103177 Pteropus vampyrus 97.96 0.00e+00 868.00
IUUC-Rno-105048 Rattus norvegicus 95.13 0.00e+00 832.00
IUUC-Sha-107429 Sarcophilus harrisii 96.36 0.00e+00 876.00
IUUC-Sar-113024 Sorex araneus 96.16 0.00e+00 820.00
IUUC-Ssc-115749 Sus scrofa 96.44 2.00e-152 531.00
IUUC-Tgu-117277 Taeniopygia guttata 94.90 0.00e+00 890.00
IUUC-Tru-117844 Takifugu rubripes 78.86 0.00e+00 735.00
IUUC-Tsy-119456 Tarsius syrichta 95.71 0.00e+00 872.00
IUUC-Tni-120251 Tetraodon nigroviridis 74.85 0.00e+00 748.00
IUUC-Tbe-127423 Tupaia belangeri 91.65 0.00e+00 796.00
IUUC-Ttr-128401 Tursiops truncatus 91.00 0.00e+00 795.00
IUUC-Vpa-130549 Vicugna pacos 88.02 3.00e-165 573.00
IUUC-Xtr-131892 Xenopus tropicalis 83.20 0.00e+00 751.00
Created Date 25-Jun-2017

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