iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013135

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02006229

Gene Name

RNF19B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000008330.5	ENSBTAT00000010969.5	ENSBTAP00000010969.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	2.70e-53	181.4	114	313

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++Cl++l++e+++ ll+C h+ C++Cl++yl+l+i+e++ + iscp  ec+e+l++++i+ ll+++ l+++ye+++l++++++d++++w
   Q: 114  CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESR-VPISCP--ECSERLNPHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRW 200
           ****************************************.9*****..89*************************************** PP
   S: 91   cpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeek......eeaeskelleanskkCpkCkvyie 172
           cpapdC ++v++  +a  +kl++e+e+c++efC++Ck++wH++++C+++++++a+t + +       ++ +++  ++++k+Cp+C++yi+
   Q: 201  CPAPDCGYAVIAYGCAscPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRtkhtsgLSYGQESGPADDIKPCPRCSAYII 290
           *************999899************************************99988888888888899999*************** PP
   S: 173  k..negCnhmtCakCkaefCwlC 193
           k  +++CnhmtCa C++efCwlC
   Q: 291  KmnDGSCNHMTCAVCGCEFCWLC 313
           997889***************** PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MGSEKDSESP RSTSLHAAAP DPKCRSGGRR RRLTFHSVFS SSARGRRARA KPQAEPPPPA 60
APPPPPAXQA SPPEALPAEP AAEAEAEAAA TVGPGLDDEE AAEGGGSGPE EVECPLCLVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTCTG AGAAAGACTC CGAGTCGCCG CGCTCTACAT CGCTACACGC GGCTGCGCCC 60
GACCCCAAGT GCCGCAGCGG CGGCCGGCGC CGGCGCCTCA CCTTCCACAG CGTCTTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0044194--C:cytolytic granule
GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002183	Ailuropoda melanoleuca	95.57	0.00e+00	1073.00
IUUC-Apl-003468	Anas platyrhynchos	89.22	0.00e+00	850.00
IUUC-Aca-004324	Anolis carolinensis	87.52	0.00e+00	957.00
IUUC-Ame-011813	Astyanax mexicanus	59.83	0.00e+00	696.00
IUUC-Cja-019264	Callithrix jacchus	86.52	0.00e+00	971.00
IUUC-Cpo-022502	Cavia porcellus	94.18	0.00e+00	956.00
IUUC-Cho-025032	Choloepus hoffmanni	74.41	0.00e+00	726.00
IUUC-Dre-028769	Danio rerio	62.21	0.00e+00	758.00
IUUC-Dor-030551	Dipodomys ordii	96.98	3.00e-119	421.00
IUUC-Ete-033008	Echinops telfairi	82.10	0.00e+00	796.00
IUUC-Eca-033267	Equus caballus	96.19	0.00e+00	927.00
IUUC-Fca-035520	Felis catus	96.57	0.00e+00	926.00
IUUC-Fal-037090	Ficedula albicollis	88.55	0.00e+00	761.00
IUUC-Gga-041229	Gallus gallus	87.98	0.00e+00	741.00
IUUC-Gac-041619	Gasterosteus aculeatus	67.23	0.00e+00	726.00
IUUC-Hsa-045958	Homo sapiens	95.65	0.00e+00	1122.00
IUUC-Itr-048425	Ictidomys tridecemlineatus	95.60	0.00e+00	964.00
IUUC-Lch-049552	Latimeria chalumnae	75.29	0.00e+00	938.00
IUUC-Loc-051738	Lepisosteus oculatus	69.18	0.00e+00	769.00
IUUC-Laf-054252	Loxodonta africana	91.98	0.00e+00	927.00
IUUC-Meu-055920	Macropus eugenii	92.78	0.00e+00	938.00
IUUC-Mga-059587	Meleagris gallopavo	87.78	0.00e+00	796.00
IUUC-Mdo-061985	Monodelphis domestica	92.50	0.00e+00	1087.00
IUUC-Mmu-064262	Mus musculus	95.46	0.00e+00	1101.00
IUUC-Mpu-066101	Mustela putorius furo	96.22	0.00e+00	1114.00
IUUC-Mlu-067347	Myotis lucifugus	94.48	0.00e+00	927.00
IUUC-Ont-071298	Oreochromis niloticus	68.67	0.00e+00	745.00
IUUC-Oan-073219	Ornithorhynchus anatinus	88.80	0.00e+00	865.00
IUUC-Ocu-073792	Oryctolagus cuniculus	93.10	0.00e+00	885.00
IUUC-Ola-086499	Oryzias latipes	68.28	0.00e+00	751.00
IUUC-Oga-088812	Otolemur garnettii	95.95	0.00e+00	1068.00
IUUC-Oar-090353	Ovis aries	98.57	0.00e+00	1006.00
IUUC-Psi-092988	Pelodiscus sinensis	89.04	0.00e+00	842.00
IUUC-Pfo-096268	Poecilia formosa	64.70	0.00e+00	744.00
IUUC-Pca-100597	Procavia capensis	95.05	0.00e+00	906.00
IUUC-Pva-102542	Pteropus vampyrus	82.82	0.00e+00	865.00
IUUC-Sha-106512	Sarcophilus harrisii	90.65	0.00e+00	1048.00
IUUC-Sar-113233	Sorex araneus	94.48	0.00e+00	881.00
IUUC-Ssc-115781	Sus scrofa	96.28	0.00e+00	1172.00
IUUC-Tgu-117384	Taeniopygia guttata	95.68	0.00e+00	775.00
IUUC-Tru-117919	Takifugu rubripes	67.30	0.00e+00	729.00
IUUC-Tsy-119275	Tarsius syrichta	90.42	0.00e+00	901.00
IUUC-Tbe-127335	Tupaia belangeri	99.73	0.00e+00	670.00
IUUC-Ttr-128554	Tursiops truncatus	95.62	0.00e+00	925.00
IUUC-Vpa-130407	Vicugna pacos	90.78	0.00e+00	927.00
IUUC-Xtr-132325	Xenopus tropicalis	84.98	0.00e+00	726.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence