iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033282

UUCD1 version

UUC-EqC-00249

Ensembl Protein ID

ENSECAP00000013820.1

UniProt Accession

F6TWL2; F6TWL2_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000015828.1	ENSECAT00000017060.1	ENSECAP00000013820.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.60e-19	69.5	33	96
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.70e-14	50.8	132	163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l v+++ f+ah+ivLaa+S++F a+f++el+e+  k+ v+i+++ ++ ++ ll+F+Yt ++
   Q: 33   CDVTLRVEQKDFPAHRIVLAACSDYFCAMFTSELSEKG-KPYVDIQGLTASTMEILLDFVYTETV 96
           9***********************************98.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fA++++c dL++aa+ f +khF+
   Q: 132  PSNCLGIRDFAETHNCVDLMQAAEVFSQKHFP 163
           89*****************************6 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MGGIMAPKDI MTNTHAKSIL NSMNSLRKSN TLCDVTLRVE QKDFPAHRIV LAACSDYFCA 60
MFTSELSEKG KPYVDIQGLT ASTMEILLDF VYTETVHVTV ENVQELLPAA CLLQLKGVKQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCAGAATC CAAGGACTCG TTTCATTCCT TCTACATATT GCTTGATGGG AGGCATTATG 60
GCCCCCAAAG ACATAATGAC AAATACTCAT GCTAAATCCA TCCTCAATTC GATGAACTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0030134--C:ER to Golgi transport vesicle
GO:0000139--C:Golgi membrane
GO:0005815--C:microtubule organizing center
GO:0048208--P:COPII vesicle coating
GO:0006513--P:protein monoubiquitination
GO:0016055--P:Wnt signaling pathway

KEGG

ecb:100052378

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002301	Ailuropoda melanoleuca	99.29	0.00e+00	1127.00
IUUC-Apl-003339	Anas platyrhynchos	96.72	0.00e+00	1028.00
IUUC-Aca-004418	Anolis carolinensis	96.10	0.00e+00	1114.00
IUUC-Ath-007066	Arabidopsis thaliana	32.63	2.00e-39	157.00
IUUC-Ame-011906	Astyanax mexicanus	76.06	0.00e+00	881.00
IUUC-Bta-012979	Bos taurus	97.36	0.00e+00	1126.00
IUUC-Cja-019582	Callithrix jacchus	98.77	0.00e+00	1143.00
IUUC-Cfa-020716	Canis familiaris	99.82	0.00e+00	1154.00
IUUC-Cpo-022013	Cavia porcellus	99.65	0.00e+00	1153.00
IUUC-Cre-022752	Chlamydomonas reinhardtii	28.76	1.00e-15	79.70
IUUC-Csa-023424	Chlorocebus sabaeus	99.62	0.00e+00	1068.00
IUUC-Cho-024586	Choloepus hoffmanni	81.34	0.00e+00	899.00
IUUC-Dre-028344	Danio rerio	89.00	4.00e-168	583.00
IUUC-Dno-028854	Dasypus novemcinctus	99.82	0.00e+00	1155.00
IUUC-Dor-030403	Dipodomys ordii	99.65	0.00e+00	1151.00
IUUC-Ete-032963	Echinops telfairi	97.81	0.00e+00	993.00
IUUC-Eeu-034933	Erinaceus europaeus	98.43	2.00e-142	499.00
IUUC-Fca-035487	Felis catus	99.82	0.00e+00	1155.00
IUUC-Fal-037059	Ficedula albicollis	95.58	0.00e+00	1107.00
IUUC-Gmo-039564	Gadus morhua	90.09	0.00e+00	1088.00
IUUC-Gga-040629	Gallus gallus	96.26	0.00e+00	1113.00
IUUC-Gac-042526	Gasterosteus aculeatus	90.64	0.00e+00	1088.00
IUUC-Ggo-044839	Gorilla gorilla	99.65	0.00e+00	1154.00
IUUC-Hsa-046742	Homo sapiens	99.65	0.00e+00	1154.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	99.65	0.00e+00	1152.00
IUUC-Lch-049540	Latimeria chalumnae	93.44	0.00e+00	1119.00
IUUC-Loc-051923	Lepisosteus oculatus	93.26	0.00e+00	1089.00
IUUC-Laf-054370	Loxodonta africana	99.30	0.00e+00	1151.00
IUUC-Mcc-054852	Macaca mulatta	99.65	0.00e+00	1154.00
IUUC-Mor-057181	Magnaporthe oryzae	26.61	1.00e-10	60.50
IUUC-Mga-059486	Meleagris gallopavo	95.11	0.00e+00	1017.00
IUUC-Mmr-061777	Microcebus murinus	99.65	0.00e+00	1151.00
IUUC-Mdo-061990	Monodelphis domestica	97.88	0.00e+00	1135.00
IUUC-Mmu-064053	Mus musculus	99.30	0.00e+00	1152.00
IUUC-Mac-064654	Musa acuminata	32.99	2.00e-40	160.00
IUUC-Mpu-066623	Mustela putorius furo	85.86	0.00e+00	822.00
IUUC-Mlu-067648	Myotis lucifugus	98.94	0.00e+00	1173.00
IUUC-Nle-069714	Nomascus leucogenys	99.47	0.00e+00	1153.00
IUUC-Opr-071143	Ochotona princeps	92.96	0.00e+00	1056.00
IUUC-Ont-071848	Oreochromis niloticus	91.31	0.00e+00	1095.00
IUUC-Oan-073041	Ornithorhynchus anatinus	97.15	1.00e-164	571.00
IUUC-Ocu-074379	Oryctolagus cuniculus	99.12	0.00e+00	1149.00
IUUC-Oin-079973	Oryza indica	32.48	7.00e-34	138.00
IUUC-Ola-087469	Oryzias latipes	91.31	0.00e+00	1095.00
IUUC-Oga-088004	Otolemur garnettii	99.58	2.00e-142	498.00
IUUC-Oar-090144	Ovis aries	98.42	0.00e+00	1138.00
IUUC-Ptr-091406	Pan troglodytes	99.65	0.00e+00	1154.00
IUUC-Pan-092762	Papio anubis	98.59	0.00e+00	1134.00
IUUC-Psi-093391	Pelodiscus sinensis	95.74	0.00e+00	1113.00
IUUC-Pma-094134	Petromyzon marinus	74.55	0.00e+00	833.00
IUUC-Pfo-096404	Poecilia formosa	91.36	0.00e+00	1097.00
IUUC-Pab-098425	Pongo abelii	98.77	0.00e+00	1139.00
IUUC-Pop-099216	Populus trichocarpa	33.74	1.00e-30	127.00
IUUC-Pca-101093	Procavia capensis	100.00	5.00e-174	603.00
IUUC-Pva-102239	Pteropus vampyrus	88.91	0.00e+00	1032.00
IUUC-Rno-104921	Rattus norvegicus	99.47	0.00e+00	1155.00
IUUC-Sha-106625	Sarcophilus harrisii	98.77	0.00e+00	1145.00
IUUC-Sly-111189	Solanum lycopersicum	35.43	4.00e-27	114.00
IUUC-Sar-113468	Sorex araneus	87.31	0.00e+00	716.00
IUUC-Ssc-116106	Sus scrofa	99.47	0.00e+00	1151.00
IUUC-Tgu-117402	Taeniopygia guttata	74.39	0.00e+00	749.00
IUUC-Tru-117546	Takifugu rubripes	90.78	0.00e+00	1090.00
IUUC-Tsy-118802	Tarsius syrichta	89.75	0.00e+00	1001.00
IUUC-Tni-119999	Tetraodon nigroviridis	90.44	0.00e+00	1084.00
IUUC-Tca-121074	Theobroma cacao	31.32	5.00e-38	152.00
IUUC-Tbe-127987	Tupaia belangeri	99.57	0.00e+00	967.00
IUUC-Ttr-128613	Tursiops truncatus	92.42	0.00e+00	1048.00
IUUC-Xtr-132401	Xenopus tropicalis	92.23	8.00e-175	605.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence