iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093934

Ensembl Protein ID

ENSPSIP00000003315.1

UniProt Accession

K7F5K5; K7F5K5_PELSI

Genbank Protein ID

ENSPSIP00000003315

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01140775

Gene Name

RNF41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000003175.1	ENSPSIT00000003330.1	ENSPSIP00000003315.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.30e-06	28.4	12	69
E3 activity/RING/RING	3.10e-06	27.7	18	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnl 59
           v e+++CpI   + ++Pv +p + + +  ++I +w++++++ cPv+r+ +t   l P  
   Q: 12   VDEDLICPICSGVLEEPVQAPhCEHAFCNACITQWFSQQQT-CPVDRSVVTVAHLRPVP 69
           56899******************************998887.******99999887764 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC   +++ p+  p C H+f+  C+ +w       s++++CP++r
   Q: 18   CPICSGVLEE-PVQAPhCEHAFCNACITQW------FSQQQTCPVDR 57
           ****999999.777777*************......********987 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MGYDVARFQG DVDEDLICPI CSGVLEEPVQ APHCEHAFCN ACITQWFSQQ QTCPVDRSVV 60
TVAHLRPVPR IMRNMLSKLQ ITCDNAVFGC TAVVRLDNLM SHLHDCEHNP KRPVTCEQGC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTCTGGCA TCGGTAATGA GCAATGGGGT ATGATGTAGC GCGCTTTCAG GGCGATGTGG 60
ACGAAGACCT TATCTGCCCC ATCTGCAGCG GGGTCCTGGA GGAGCCAGTG CAGGTAGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008974--TRAF-like
IPR015036--USP8_interacting
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF08941--USP8_interact

SMART

SM00184--RING

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0031386--F:protein tag
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0030336--P:negative regulation of cell migration
GO:0008285--P:negative regulation of cell proliferation
GO:1901525--P:negative regulation of macromitophagy
GO:2000379--P:positive regulation of reactive oxygen species metabolic process
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0010498--P:proteasomal protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:2000114--P:regulation of establishment of cell polarity
GO:0045619--P:regulation of lymphocyte differentiation
GO:0043408--P:regulation of MAPK cascade
GO:0045637--P:regulation of myeloid cell differentiation
GO:0051896--P:regulation of protein kinase B signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002398	Ailuropoda melanoleuca	89.31	3.00e-168	583.00
IUUC-Apl-003568	Anas platyrhynchos	91.22	3.00e-168	583.00
IUUC-Aca-005119	Anolis carolinensis	91.82	8.00e-172	595.00
IUUC-Ame-010708	Astyanax mexicanus	84.28	8.00e-162	562.00
IUUC-Bta-013428	Bos taurus	83.33	5.00e-156	543.00
IUUC-Cja-019844	Callithrix jacchus	89.34	3.00e-167	580.00
IUUC-Cfa-021124	Canis familiaris	89.62	1.00e-168	585.00
IUUC-Cpo-022325	Cavia porcellus	89.31	3.00e-168	583.00
IUUC-Csa-023113	Chlorocebus sabaeus	89.62	1.00e-168	585.00
IUUC-Cho-024991	Choloepus hoffmanni	96.91	7.00e-112	395.00
IUUC-Cne-026870	Cryptococcus neoformans	38.52	6.00e-20	92.00
IUUC-Dre-028730	Danio rerio	83.96	1.00e-161	561.00
IUUC-Dno-028908	Dasypus novemcinctus	88.54	2.00e-149	521.00
IUUC-Dor-030411	Dipodomys ordii	89.31	2.00e-168	584.00
IUUC-Dme-031868	Drosophila melanogaster	53.97	2.00e-99	355.00
IUUC-Ete-032896	Echinops telfairi	70.30	2.00e-104	371.00
IUUC-Eca-034135	Equus caballus	89.62	1.00e-168	585.00
IUUC-Eeu-034675	Erinaceus europaeus	89.31	5.00e-168	582.00
IUUC-Fca-035612	Felis catus	89.62	1.00e-168	585.00
IUUC-Fal-036922	Ficedula albicollis	96.30	8.00e-42	160.00
IUUC-Gmo-039648	Gadus morhua	80.82	2.00e-155	541.00
IUUC-Gga-040474	Gallus gallus	92.14	2.00e-172	597.00
IUUC-Gac-041951	Gasterosteus aculeatus	82.08	4.00e-158	550.00
IUUC-Ggo-045126	Gorilla gorilla	89.34	3.00e-167	580.00
IUUC-Hsa-046402	Homo sapiens	89.62	1.00e-168	585.00
IUUC-Itr-047895	Ictidomys tridecemlineatus	89.62	1.00e-168	585.00
IUUC-Lch-050266	Latimeria chalumnae	86.16	2.00e-164	571.00
IUUC-Loc-052547	Lepisosteus oculatus	85.22	1.00e-162	565.00
IUUC-Lma-053014	Leptosphaeria maculans	34.68	2.00e-12	67.00
IUUC-Laf-054332	Loxodonta africana	89.03	5.00e-167	579.00
IUUC-Mcc-055869	Macaca mulatta	89.62	1.00e-168	585.00
IUUC-Meu-056735	Macropus eugenii	88.89	6.00e-150	522.00
IUUC-Mga-060100	Meleagris gallopavo	92.14	2.00e-172	597.00
IUUC-Mmr-061382	Microcebus murinus	89.62	1.00e-168	585.00
IUUC-Mmu-064225	Mus musculus	89.31	3.00e-168	583.00
IUUC-Mpu-066709	Mustela putorius furo	89.62	1.00e-168	585.00
IUUC-Mlu-067168	Myotis lucifugus	88.68	1.00e-167	582.00
IUUC-Nle-070176	Nomascus leucogenys	89.62	1.00e-168	585.00
IUUC-Opr-070259	Ochotona princeps	89.31	3.00e-168	583.00
IUUC-Ont-071235	Oreochromis niloticus	83.33	3.00e-160	556.00
IUUC-Oan-072850	Ornithorhynchus anatinus	49.84	9.00e-71	259.00
IUUC-Ocu-074165	Oryctolagus cuniculus	89.31	3.00e-168	583.00
IUUC-Ola-086658	Oryzias latipes	81.76	2.00e-156	544.00
IUUC-Oga-088933	Otolemur garnettii	89.62	1.00e-168	585.00
IUUC-Oar-090089	Ovis aries	89.31	2.00e-168	584.00
IUUC-Ptr-091263	Pan troglodytes	89.62	1.00e-168	585.00
IUUC-Pan-092926	Papio anubis	89.62	1.00e-168	585.00
IUUC-Pma-094578	Petromyzon marinus	61.44	3.00e-109	387.00
IUUC-Pno-094854	Phaeosphaeria nodorum	36.59	2.00e-13	70.10
IUUC-Pfo-097431	Poecilia formosa	83.33	6.00e-160	556.00
IUUC-Pab-097852	Pongo abelii	89.62	1.00e-168	585.00
IUUC-Pca-100496	Procavia capensis	81.50	4.00e-147	513.00
IUUC-Ppe-101708	Prunus persica	28.70	2.00e-06	48.10
IUUC-Pva-103157	Pteropus vampyrus	96.50	5.00e-114	402.00
IUUC-Pgr-103416	Puccinia graminis	31.73	6.00e-14	72.00
IUUC-Ptt-103724	Puccinia triticina	26.56	6.00e-05	42.00
IUUC-Rno-105928	Rattus norvegicus	89.31	5.00e-168	583.00
IUUC-Sha-107556	Sarcophilus harrisii	89.66	1.00e-167	581.00
IUUC-Sar-113208	Sorex araneus	89.62	1.00e-168	585.00
IUUC-Ssc-116011	Sus scrofa	89.31	2.00e-168	584.00
IUUC-Tgu-116882	Taeniopygia guttata	65.83	5.00e-61	226.00
IUUC-Tru-117987	Takifugu rubripes	83.02	2.00e-159	554.00
IUUC-Tsy-118785	Tarsius syrichta	89.31	1.00e-166	578.00
IUUC-Tni-120165	Tetraodon nigroviridis	82.70	5.00e-159	553.00
IUUC-Tbe-127920	Tupaia belangeri	97.00	5.00e-116	409.00
IUUC-Ttr-129160	Tursiops truncatus	88.99	6.00e-168	582.00
IUUC-Vda-129938	Verticillium dahliae	39.32	3.00e-19	90.10
IUUC-Vpa-130629	Vicugna pacos	89.62	1.00e-168	585.00
IUUC-Xtr-131895	Xenopus tropicalis	88.36	5.00e-167	579.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence