iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000000630.3	ENSMMUT00000000906.3	ENSMMUP00000000844.2
ENSMMUG00000000630.3	ENSMMUT00000060679.1	ENSMMUP00000042796.1
ENSMMUG00000000630.3	ENSMMUT00000062069.1	ENSMMUP00000046279.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.12	0.00e+00	2074.00	IUUC-Hsa-046163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MPVQAPQWTD FLSCPICTQT FDETIRKPIS LGCGHTVCKM CLNKLHRKAC PFDQTTINTD 60
IELLPVNSAL LQLVGAQVPE QQPITLCSGV EDTKHYEEAK KCVEELALYL KPLSSARGVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCTTGTAA TGGAAGTTGA GTTACTTGCT TCACCTAAAC AAGGAAGTTG GCATGTTTGC 60
CTAGCAACAG TCGCTAAAAC CTTCTGTTGT GGAAGGTTCC CTAGGAGTGA GAAGAAGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032671--RC3H1
IPR027370--Znf-RING_LisH
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00642--zf-CCCH
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0000932--C:P-body
GO:0003730--F:mRNA 3'-UTR binding
GO:0035613--F:RNA stem-loop binding
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0001782--P:B cell homeostasis
GO:0071347--P:cellular response to interleukin-1
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048535--P:lymph node development
GO:0046007--P:negative regulation of activated T cell proliferation
GO:0030889--P:negative regulation of B cell proliferation
GO:0002635--P:negative regulation of germinal center formation
GO:0045623--P:negative regulation of T-helper cell differentiation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0048536--P:spleen development
GO:0043029--P:T cell homeostasis
GO:0042098--P:T cell proliferation
GO:0061470--P:T follicular helper cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001700	Ailuropoda melanoleuca	96.91	0.00e+00	1960.00
IUUC-Apl-003290	Anas platyrhynchos	87.09	0.00e+00	1849.00
IUUC-Aca-004905	Anolis carolinensis	84.99	0.00e+00	1754.00
IUUC-Ame-011475	Astyanax mexicanus	64.18	0.00e+00	1211.00
IUUC-Cja-019907	Callithrix jacchus	98.50	0.00e+00	2060.00
IUUC-Cfa-020679	Canis familiaris	96.82	0.00e+00	1959.00
IUUC-Cpo-022110	Cavia porcellus	91.90	0.00e+00	1939.00
IUUC-Csa-024166	Chlorocebus sabaeus	99.36	0.00e+00	2000.00
IUUC-Dno-029870	Dasypus novemcinctus	95.50	0.00e+00	981.00
IUUC-Dor-030934	Dipodomys ordii	87.34	0.00e+00	1493.00
IUUC-Dme-031708	Drosophila melanogaster	64.51	8.00e-163	567.00
IUUC-Ete-032652	Echinops telfairi	96.41	0.00e+00	1392.00
IUUC-Eca-033236	Equus caballus	96.56	0.00e+00	1933.00
IUUC-Eeu-035091	Erinaceus europaeus	83.30	0.00e+00	877.00
IUUC-Fca-035773	Felis catus	97.35	0.00e+00	1966.00
IUUC-Fal-036972	Ficedula albicollis	86.55	0.00e+00	1850.00
IUUC-Gmo-039303	Gadus morhua	80.07	0.00e+00	892.00
IUUC-Ggo-044691	Gorilla gorilla	92.71	0.00e+00	1905.00
IUUC-Hsa-046163	Homo sapiens	99.12	0.00e+00	2074.00
IUUC-Itr-048266	Ictidomys tridecemlineatus	93.97	0.00e+00	1063.00
IUUC-Lch-050667	Latimeria chalumnae	74.76	0.00e+00	1539.00
IUUC-Loc-052404	Lepisosteus oculatus	69.20	0.00e+00	1330.00
IUUC-Laf-053618	Loxodonta africana	97.45	0.00e+00	1912.00
IUUC-Meu-056025	Macropus eugenii	85.49	0.00e+00	938.00
IUUC-Mmr-061188	Microcebus murinus	97.44	0.00e+00	1970.00
IUUC-Mdo-063035	Monodelphis domestica	92.33	0.00e+00	1891.00
IUUC-Mmu-064146	Mus musculus	92.94	0.00e+00	1946.00
IUUC-Mpu-066217	Mustela putorius furo	96.29	0.00e+00	1944.00
IUUC-Mlu-068023	Myotis lucifugus	95.50	0.00e+00	1958.00
IUUC-Nle-069506	Nomascus leucogenys	99.03	0.00e+00	2077.00
IUUC-Opr-070587	Ochotona princeps	83.02	0.00e+00	1595.00
IUUC-Ont-071278	Oreochromis niloticus	63.05	0.00e+00	1197.00
IUUC-Oan-073500	Ornithorhynchus anatinus	91.70	0.00e+00	1957.00
IUUC-Ocu-074299	Oryctolagus cuniculus	95.97	0.00e+00	1843.00
IUUC-Ola-086665	Oryzias latipes	61.47	0.00e+00	1213.00
IUUC-Oga-088519	Otolemur garnettii	90.22	0.00e+00	1757.00
IUUC-Oar-089246	Ovis aries	96.49	0.00e+00	1846.00
IUUC-Ptr-091102	Pan troglodytes	99.21	0.00e+00	2076.00
IUUC-Pan-091952	Papio anubis	99.56	0.00e+00	2084.00
IUUC-Pfo-097227	Poecilia formosa	61.79	0.00e+00	1173.00
IUUC-Pab-097975	Pongo abelii	95.76	0.00e+00	1981.00
IUUC-Pca-101127	Procavia capensis	91.66	0.00e+00	1314.00
IUUC-Pva-102431	Pteropus vampyrus	87.82	0.00e+00	1740.00
IUUC-Sha-106690	Sarcophilus harrisii	91.19	0.00e+00	1905.00
IUUC-Ssc-116189	Sus scrofa	97.35	0.00e+00	1905.00
IUUC-Tgu-116527	Taeniopygia guttata	87.37	0.00e+00	1858.00
IUUC-Tru-118389	Takifugu rubripes	62.46	0.00e+00	1226.00
IUUC-Tsy-119193	Tarsius syrichta	93.56	0.00e+00	1889.00
IUUC-Tni-119790	Tetraodon nigroviridis	63.83	0.00e+00	1114.00
IUUC-Tbe-127445	Tupaia belangeri	90.91	0.00e+00	1538.00
IUUC-Ttr-128877	Tursiops truncatus	96.74	0.00e+00	1897.00
IUUC-Vpa-130054	Vicugna pacos	94.43	0.00e+00	912.00
IUUC-Xtr-132274	Xenopus tropicalis	78.66	0.00e+00	1604.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence