iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066261

Ensembl Protein ID

ENSMPUP00000000558.1

UniProt Accession

M3XNA8; M3XNA8_MUSPF

Genbank Protein ID

ENSMPUP00000000558

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01014742

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000000564.1	ENSMPUT00000000570.1	ENSMPUP00000000558.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	4.80e-44	148.8	112	183

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktLvqkegWfrefl 73
           ++e ++ll++lq++++ +L+v+dvldk+++  ll++e+++++ aae++gn++++++LLk++vqke+Wf+efl
   Q: 112  HDECLQLLNLLQPTLVNRLLVRDVLDKCVEKKLLTNEDRNRISAAENNGNESGVRELLKRIVQKENWFSEFL 183
           89*********************************************************************6 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

KMSNGYSADK SFCYLISCFR ARVKTYIQVE PVLDYLDFLP NDVKEQIQRT AVNAGNMQAA 60
DELLNALEKG GWPPGWPRQF LVALQRAGSV LAARYLNPEL TDLPSPSSEN AHDECLQLLN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGATGTCGA ACGGCTATTC TGCAGACAAG AGTTTCTGCT ATCTCATCTC GTGTTTCAGG 60
GCCAGAGTGA AAACGTACAT CCAGGTGGAG CCGGTGCTGG ACTACCTGGA CTTTCTGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR001315--CARD
IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS50209--CARD
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation
GO:0042981--P:regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	93.39	0.00e+00	1813.00
IUUC-Apl-003900	Anas platyrhynchos	59.77	0.00e+00	1154.00
IUUC-Aca-005329	Anolis carolinensis	58.43	0.00e+00	989.00
IUUC-Ame-011305	Astyanax mexicanus	48.06	0.00e+00	873.00
IUUC-Bta-012361	Bos taurus	81.56	0.00e+00	1533.00
IUUC-Cja-018760	Callithrix jacchus	82.65	0.00e+00	1533.00
IUUC-Cfa-020321	Canis familiaris	89.35	0.00e+00	1688.00
IUUC-Cpo-022450	Cavia porcellus	76.68	0.00e+00	1499.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	33.33	1.00e-12	68.90
IUUC-Csa-024194	Chlorocebus sabaeus	84.41	0.00e+00	1532.00
IUUC-Cho-024364	Choloepus hoffmanni	73.53	0.00e+00	1012.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	22.56	2.00e-22	102.00
IUUC-Dre-028305	Danio rerio	53.43	0.00e+00	703.00
IUUC-Dno-029831	Dasypus novemcinctus	82.46	0.00e+00	1601.00
IUUC-Dor-030410	Dipodomys ordii	74.97	0.00e+00	1178.00
IUUC-Ete-032950	Echinops telfairi	75.46	0.00e+00	627.00
IUUC-Eca-034279	Equus caballus	84.31	0.00e+00	1597.00
IUUC-Eeu-034678	Erinaceus europaeus	78.46	0.00e+00	1495.00
IUUC-Fca-035618	Felis catus	93.32	0.00e+00	1046.00
IUUC-Fal-037106	Ficedula albicollis	67.31	0.00e+00	952.00
IUUC-Gmo-038598	Gadus morhua	48.61	0.00e+00	659.00
IUUC-Gga-040467	Gallus gallus	59.61	0.00e+00	1150.00
IUUC-Gac-042316	Gasterosteus aculeatus	46.61	0.00e+00	812.00
IUUC-Ggo-045461	Gorilla gorilla	83.82	0.00e+00	1521.00
IUUC-Hsa-045771	Homo sapiens	83.72	0.00e+00	1518.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	80.70	0.00e+00	1508.00
IUUC-Lch-049913	Latimeria chalumnae	65.09	0.00e+00	902.00
IUUC-Loc-052768	Lepisosteus oculatus	52.79	0.00e+00	956.00
IUUC-Laf-053933	Loxodonta africana	81.92	0.00e+00	1547.00
IUUC-Mcc-054695	Macaca mulatta	84.50	0.00e+00	1536.00
IUUC-Meu-056829	Macropus eugenii	72.27	0.00e+00	1084.00
IUUC-Mga-059205	Meleagris gallopavo	59.73	0.00e+00	1149.00
IUUC-Mmr-060703	Microcebus murinus	83.65	0.00e+00	1528.00
IUUC-Mdo-063079	Monodelphis domestica	69.07	0.00e+00	1374.00
IUUC-Mmu-064066	Mus musculus	76.53	0.00e+00	1502.00
IUUC-Mlu-068196	Myotis lucifugus	81.58	0.00e+00	1546.00
IUUC-Nle-069479	Nomascus leucogenys	81.68	0.00e+00	1489.00
IUUC-Opr-070717	Ochotona princeps	71.71	0.00e+00	1093.00
IUUC-Ont-071702	Oreochromis niloticus	46.56	0.00e+00	838.00
IUUC-Oan-073639	Ornithorhynchus anatinus	65.12	0.00e+00	1150.00
IUUC-Ocu-074521	Oryctolagus cuniculus	81.89	0.00e+00	1570.00
IUUC-Ola-086351	Oryzias latipes	46.27	0.00e+00	809.00
IUUC-Oga-088539	Otolemur garnettii	79.63	0.00e+00	1474.00
IUUC-Oar-090186	Ovis aries	81.27	0.00e+00	1524.00
IUUC-Ptr-090575	Pan troglodytes	81.29	0.00e+00	1478.00
IUUC-Pan-092371	Papio anubis	84.70	0.00e+00	1539.00
IUUC-Psi-093072	Pelodiscus sinensis	62.44	0.00e+00	1218.00
IUUC-Pma-094345	Petromyzon marinus	42.03	9.00e-89	320.00
IUUC-Pfo-096401	Poecilia formosa	51.32	0.00e+00	671.00
IUUC-Pab-097623	Pongo abelii	82.55	0.00e+00	1508.00
IUUC-Pca-100993	Procavia capensis	75.94	0.00e+00	1272.00
IUUC-Pva-102227	Pteropus vampyrus	78.17	0.00e+00	1446.00
IUUC-Rno-105198	Rattus norvegicus	75.88	0.00e+00	1520.00
IUUC-Sha-107622	Sarcophilus harrisii	71.25	0.00e+00	1381.00
IUUC-Spo-108161	Schizosaccharomyces pombe	28.16	3.30e-02	34.30
IUUC-Sar-113625	Sorex araneus	67.52	0.00e+00	713.00
IUUC-Tgu-117486	Taeniopygia guttata	59.63	0.00e+00	1100.00
IUUC-Tru-118445	Takifugu rubripes	45.89	0.00e+00	821.00
IUUC-Tsy-119512	Tarsius syrichta	80.70	0.00e+00	1435.00
IUUC-Tni-120711	Tetraodon nigroviridis	45.38	0.00e+00	828.00
IUUC-Tbe-127644	Tupaia belangeri	72.32	0.00e+00	1296.00
IUUC-Ttr-128989	Tursiops truncatus	78.73	0.00e+00	1513.00
IUUC-Vpa-130587	Vicugna pacos	78.60	0.00e+00	1242.00
IUUC-Xtr-132127	Xenopus tropicalis	52.27	0.00e+00	981.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence