iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053560

UUCD1 version

UUC-LoA-00938

Ensembl Protein ID

ENSLAFP00000028095.1

UniProt Accession

G3UJT6; G3UJT6_LOXAF

Protein Name

Uncharacterized protein

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009745.3	ENSLAFT00000009744.3	ENSLAFP00000028095.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	2.70e-15	56.4	153	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l ++ +SLqhLCRl I++c+g+     i++LPLP +LkdYL+++++q
   Q: 153  TKPLYTSAPSLQHLCRLIINKCTGT-----IWGLPLPTRLKDYLEEYKFQ 197
           678999*******************.....8***************9886 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MTLRCLEPSG NGAEGTRSQW GIAASAEEPS PEAARLATAL RELSQTGWYW GSMTVNEAKE 60
KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII CVKSKLKQFD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCTGC GGTGCCTCGA GCCCTCCGGG AATGGCGCGG AAGGGACGCG GAGCCAGTGG 60
GGTATCGCGG CCTCGGCGGA GGAGCCGTCT CCGGAGGCAG CGCGTCTGGC GACGGCCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

KEGG

lav:100660067

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	94.95	4.00e-103	366.00
IUUC-Apl-003484	Anas platyrhynchos	79.74	2.00e-72	264.00
IUUC-Aca-004253	Anolis carolinensis	71.34	5.00e-72	263.00
IUUC-Ath-007106	Arabidopsis thaliana	35.59	2.30e-02	33.10
IUUC-Ame-011267	Astyanax mexicanus	63.47	1.00e-60	225.00
IUUC-Bta-013183	Bos taurus	93.43	4.00e-97	346.00
IUUC-Bra-017915	Brassica rapa	33.90	4.20e-02	32.00
IUUC-Cja-018862	Callithrix jacchus	94.95	2.00e-99	353.00
IUUC-Cfa-020226	Canis familiaris	93.91	4.00e-96	343.00
IUUC-Cpo-022414	Cavia porcellus	93.94	1.00e-102	364.00
IUUC-Csa-023758	Chlorocebus sabaeus	94.44	2.00e-103	367.00
IUUC-Cho-024471	Choloepus hoffmanni	83.97	1.00e-70	258.00
IUUC-Dre-028288	Danio rerio	57.73	2.00e-63	234.00
IUUC-Dno-029036	Dasypus novemcinctus	94.44	2.00e-103	367.00
IUUC-Dor-030447	Dipodomys ordii	97.35	5.00e-86	308.00
IUUC-Ete-033023	Echinops telfairi	92.93	2.00e-109	387.00
IUUC-Fca-036469	Felis catus	94.95	2.00e-98	351.00
IUUC-Fal-036642	Ficedula albicollis	77.92	9.00e-71	259.00
IUUC-Gmo-039331	Gadus morhua	66.30	2.00e-35	140.00
IUUC-Gga-040809	Gallus gallus	76.73	7.00e-73	265.00
IUUC-Gac-041398	Gasterosteus aculeatus	59.52	4.00e-59	220.00
IUUC-Ggo-045341	Gorilla gorilla	95.45	1.00e-99	354.00
IUUC-Hsa-046557	Homo sapiens	94.95	3.00e-111	393.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	79.05	9.00e-91	325.00
IUUC-Lch-050160	Latimeria chalumnae	62.91	4.00e-50	190.00
IUUC-Loc-051825	Lepisosteus oculatus	63.69	5.00e-62	229.00
IUUC-Mcc-055890	Macaca mulatta	94.44	3.00e-98	350.00
IUUC-Meu-056218	Macropus eugenii	80.81	2.00e-95	340.00
IUUC-Mga-059755	Meleagris gallopavo	78.95	4.00e-71	260.00
IUUC-Mmr-061387	Microcebus murinus	94.95	4.00e-103	366.00
IUUC-Mdo-062383	Monodelphis domestica	81.82	2.00e-95	340.00
IUUC-Mmu-063443	Mus musculus	92.93	9.00e-101	358.00
IUUC-Mpu-066459	Mustela putorius furo	94.44	4.00e-98	350.00
IUUC-Mlu-068040	Myotis lucifugus	94.95	5.00e-104	369.00
IUUC-Nle-069016	Nomascus leucogenys	90.91	8.00e-97	345.00
IUUC-Opr-071087	Ochotona princeps	87.88	2.00e-101	360.00
IUUC-Ont-072340	Oreochromis niloticus	60.34	7.00e-60	223.00
IUUC-Oan-073443	Ornithorhynchus anatinus	76.50	2.00e-87	314.00
IUUC-Ocu-074539	Oryctolagus cuniculus	94.42	2.00e-98	351.00
IUUC-Ogu-078951	Oryza glumaepatula	25.86	3.90e-02	32.70
IUUC-Oin-079476	Oryza indica	25.86	3.90e-02	32.70
IUUC-Oni-082613	Oryza nivara	25.86	3.90e-02	32.70
IUUC-Oru-085265	Oryza rufipogon	25.86	4.10e-02	32.70
IUUC-Ola-087004	Oryzias latipes	60.13	2.00e-55	207.00
IUUC-Oga-088438	Otolemur garnettii	94.44	2.00e-103	367.00
IUUC-Oar-089932	Ovis aries	93.43	6.00e-97	345.00
IUUC-Ptr-091037	Pan troglodytes	95.45	1.00e-99	354.00
IUUC-Pan-092767	Papio anubis	94.44	1.00e-98	351.00
IUUC-Psi-093099	Pelodiscus sinensis	76.10	1.00e-72	265.00
IUUC-Pma-094671	Petromyzon marinus	46.43	2.00e-37	149.00
IUUC-Pfo-097073	Poecilia formosa	50.52	3.00e-55	207.00
IUUC-Pab-098319	Pongo abelii	94.95	4.00e-104	369.00
IUUC-Pca-101117	Procavia capensis	93.94	6.00e-100	356.00
IUUC-Pva-102117	Pteropus vampyrus	93.43	1.00e-95	341.00
IUUC-Rno-105913	Rattus norvegicus	92.42	5.00e-100	356.00
IUUC-Sha-106500	Sarcophilus harrisii	82.23	9.00e-95	338.00
IUUC-Ssc-115252	Sus scrofa	94.95	7.00e-104	369.00
IUUC-Tgu-117524	Taeniopygia guttata	76.10	2.00e-70	257.00
IUUC-Tsy-119335	Tarsius syrichta	93.38	1.00e-83	301.00
IUUC-Tni-120263	Tetraodon nigroviridis	53.51	1.00e-55	208.00
IUUC-Tbe-127915	Tupaia belangeri	93.43	2.00e-95	340.00
IUUC-Ttr-128372	Tursiops truncatus	94.44	3.00e-103	367.00
IUUC-Vpa-130422	Vicugna pacos	97.35	8.00e-86	308.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence