iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033819

UUCD1 version

UUC-EqC-00896

Ensembl Protein ID

ENSECAP00000017955.1

UniProt Accession

F7E408; F7E408_HORSE

Protein Name

Uncharacterized protein

Gene Name

BIRC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000019545.1	ENSECAT00000021569.1	ENSECAP00000017773.1
ENSECAG00000019545.1	ENSECAT00000021772.1	ENSECAP00000017955.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.50e-32	111.7	4558	4713

Active Site

Position(s)	Description	Evidence
4646	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp....egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.....ifhPnvyen 78
           Rl++e+ +l+++ p    +++++++++e  l+ ++vli+Gp+dtpY++g+F+++++fp+dYP++PP v+++t+     +f+Pn y++
   Q: 4558 RLAQEAVTLSTSLPlsssSSVFVRCDEE-RLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTgghsvRFNPN-YND 4642
           8999999999998877768899999999.6*****************************************************.899 PP
   S: 79   GkvClsilk.....eeekWsp.alsvesvllsiqsll..aepnpesplneeaa...ellkknreeykkkvre 139
           GkvClsil+     +eekW+p ++s+ +vl+s+qsl+  aep++++p +e+++   + ++++re y+ ++r+
   Q: 4643 GKVCLSILNtwhgrPEEKWNPqTSSFLQVLVSVQSLIlvAEPYFNEPGYERSRgtpSGTQSSRE-YDGNIRQ 4713
           ********7788889******8899***********999***********99866555666655.9998875 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAAAAAATSG PGCSSAGGGA PGVSECLVLR DCMRCDAYGL HSLSYHAALN AILAVTSHGT 60
IKVIDGTSGA TLQASALRAK PGGQVKCQYI SAVDKVIFVD DYAVGCRKDL NGILLLDTAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGCGCCCG AACGTCCCGC GTGCGTGCCG GCGCCTGACT TCACTTCCGG CTAACGCGCT 60
CGTTTGCCCC CTGCCCCGGA TGGTGACTGG CGGTGGTGCT GCACCTCGCG GGACTGTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001370--BIR_rpt
IPR022103--BIRC6
IPR008979--Galactose-bd-like
IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50143--BIR_REPEAT_2
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00653--BIR
PF12356--BIRC6
PF00179--UQ_con

SMART

SM00238--BIR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005768--C:endosome
GO:0016020--C:membrane
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0000922--C:spindle pole
GO:0005802--C:trans-Golgi network
GO:0004869--F:cysteine-type endopeptidase inhibitor activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006915--P:apoptotic process
GO:0060711--P:labyrinthine layer development
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0008284--P:positive regulation of cell proliferation
GO:0032465--P:regulation of cytokinesis
GO:0009966--P:regulation of signal transduction
GO:0060712--P:spongiotrophoblast layer development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001583	Ailuropoda melanoleuca	98.10	0.00e+00	8779.00
IUUC-Atr-003108	Amborella trichopoda	42.31	3.00e-43	169.00
IUUC-Apl-004144	Anas platyrhynchos	92.67	0.00e+00	5654.00
IUUC-Aca-005257	Anolis carolinensis	89.75	0.00e+00	8055.00
IUUC-Ath-007217	Arabidopsis thaliana	37.84	6.00e-42	165.00
IUUC-Ame-011337	Astyanax mexicanus	77.82	0.00e+00	6671.00
IUUC-Bta-012501	Bos taurus	97.16	0.00e+00	8589.00
IUUC-Bdi-014931	Brachypodium distachyon	36.69	1.00e-44	173.00
IUUC-Bol-015976	Brassica oleracea	45.76	8.00e-44	171.00
IUUC-Bra-017967	Brassica rapa	45.76	4.00e-44	172.00
IUUC-Cel-018661	Caenorhabditis elegans	36.14	3.00e-77	282.00
IUUC-Cja-018746	Callithrix jacchus	97.32	0.00e+00	8644.00
IUUC-Cfa-020170	Canis familiaris	98.22	0.00e+00	8630.00
IUUC-Cpo-022138	Cavia porcellus	97.03	0.00e+00	5824.00
IUUC-Cre-022768	Chlamydomonas reinhardtii	44.13	8.00e-43	166.00
IUUC-Csa-023927	Chlorocebus sabaeus	97.21	0.00e+00	8623.00
IUUC-Cho-024890	Choloepus hoffmanni	94.42	0.00e+00	1942.00
IUUC-Cne-026995	Cryptococcus neoformans	42.21	1.00e-35	144.00
IUUC-Dre-027941	Danio rerio	78.28	0.00e+00	5338.00
IUUC-Dno-028913	Dasypus novemcinctus	95.79	0.00e+00	8546.00
IUUC-Dor-030715	Dipodomys ordii	94.29	0.00e+00	1943.00
IUUC-Dse-031232	Dothistroma septosporum	43.96	3.00e-36	147.00
IUUC-Dme-031592	Drosophila melanogaster	52.66	0.00e+00	659.00
IUUC-Ete-032587	Echinops telfairi	77.96	0.00e+00	2077.00
IUUC-Eeu-034863	Erinaceus europaeus	87.52	0.00e+00	2561.00
IUUC-Fca-035505	Felis catus	95.25	0.00e+00	8390.00
IUUC-Fal-037318	Ficedula albicollis	92.19	0.00e+00	8236.00
IUUC-Gmo-039521	Gadus morhua	80.52	0.00e+00	1671.00
IUUC-Ggr-040040	Gaeumannomyces graminis	46.41	2.00e-31	131.00
IUUC-Gga-040728	Gallus gallus	92.12	0.00e+00	8156.00
IUUC-Gac-042251	Gasterosteus aculeatus	84.27	0.00e+00	1785.00
IUUC-Ggo-045562	Gorilla gorilla	94.89	0.00e+00	1575.00
IUUC-Hsa-046339	Homo sapiens	97.53	0.00e+00	8587.00
IUUC-Hvu-047441	Hordeum vulgare	46.15	3.00e-45	176.00
IUUC-Itr-048099	Ictidomys tridecemlineatus	97.38	0.00e+00	2713.00
IUUC-Lch-050164	Latimeria chalumnae	85.56	0.00e+00	7505.00
IUUC-Lpe-051294	Leersia perrieri	39.85	2.00e-45	176.00
IUUC-Loc-052800	Lepisosteus oculatus	84.91	0.00e+00	7493.00
IUUC-Laf-054034	Loxodonta africana	96.47	0.00e+00	8579.00
IUUC-Mcc-055267	Macaca mulatta	97.43	0.00e+00	8636.00
IUUC-Meu-056461	Macropus eugenii	92.28	0.00e+00	1231.00
IUUC-Mpo-057396	Magnaporthe poae	48.39	1.00e-32	135.00
IUUC-Mtr-057797	Medicago truncatula	39.11	2.00e-45	176.00
IUUC-Mla-059114	Melampsora laricipopulina	28.12	1.00e-38	154.00
IUUC-Mga-059594	Meleagris gallopavo	92.22	0.00e+00	7768.00
IUUC-Mmr-061179	Microcebus murinus	97.55	0.00e+00	8630.00
IUUC-Mdo-062990	Monodelphis domestica	93.85	0.00e+00	8203.00
IUUC-Mmu-063825	Mus musculus	95.05	0.00e+00	8428.00
IUUC-Mac-064881	Musa acuminata	42.86	4.00e-40	158.00
IUUC-Mpu-065908	Mustela putorius furo	97.62	0.00e+00	5573.00
IUUC-Mlu-067106	Myotis lucifugus	96.67	0.00e+00	8600.00
IUUC-Nle-069347	Nomascus leucogenys	97.63	0.00e+00	8643.00
IUUC-Opr-070799	Ochotona princeps	87.08	0.00e+00	2530.00
IUUC-Ont-072046	Oreochromis niloticus	79.03	0.00e+00	6782.00
IUUC-Oan-073415	Ornithorhynchus anatinus	92.73	0.00e+00	3380.00
IUUC-Ocu-074556	Oryctolagus cuniculus	96.90	0.00e+00	8564.00
IUUC-Oba-075602	Oryza barthii	38.89	2.00e-38	153.00
IUUC-Obr-076463	Oryza brachyantha	36.12	7.00e-46	177.00
IUUC-Ogl-077040	Oryza glaberrima	38.89	2.00e-38	153.00
IUUC-Ogu-078917	Oryza glumaepatula	38.89	2.00e-38	153.00
IUUC-Oin-079561	Oryza indica	38.89	2.00e-38	153.00
IUUC-Olo-080416	Oryza longistaminata	40.37	5.00e-39	157.00
IUUC-Ome-081384	Oryza meridionalis	38.89	3.00e-38	153.00
IUUC-Oni-082241	Oryza nivara	38.89	2.00e-38	153.00
IUUC-Opu-083659	Oryza punctata	37.68	9.00e-45	174.00
IUUC-Oru-084622	Oryza rufipogon	38.89	2.00e-38	153.00
IUUC-Osa-085920	Oryza sativa	38.89	2.00e-38	153.00
IUUC-Ola-087459	Oryzias latipes	82.25	0.00e+00	2876.00
IUUC-Oga-088251	Otolemur garnettii	95.07	0.00e+00	8222.00
IUUC-Oar-090367	Ovis aries	97.62	0.00e+00	8601.00
IUUC-Ptr-091512	Pan troglodytes	97.59	0.00e+00	8631.00
IUUC-Pan-092222	Papio anubis	96.83	0.00e+00	8589.00
IUUC-Pma-094574	Petromyzon marinus	61.12	0.00e+00	2991.00
IUUC-Ppa-095592	Physcomitrella patens	29.50	7.00e-53	202.00
IUUC-Pfo-097086	Poecilia formosa	77.65	0.00e+00	6809.00
IUUC-Pab-098390	Pongo abelii	95.95	0.00e+00	8410.00
IUUC-Pop-099284	Populus trichocarpa	37.35	2.00e-40	160.00
IUUC-Pca-101036	Procavia capensis	88.89	0.00e+00	4135.00
IUUC-Pva-103053	Pteropus vampyrus	92.74	0.00e+00	3601.00
IUUC-Pte-104333	Pyrenophora teres	40.80	6.00e-42	166.00
IUUC-Pyt-104498	Pyrenophora triticirepentis	38.96	3.00e-42	167.00
IUUC-Rno-106049	Rattus norvegicus	95.32	0.00e+00	6896.00
IUUC-Sha-107483	Sarcophilus harrisii	90.90	0.00e+00	7768.00
IUUC-Smo-108915	Selaginella moellendorffii	42.59	2.00e-42	166.00
IUUC-Sly-110929	Solanum lycopersicum	38.15	2.00e-44	174.00
IUUC-Stu-112554	Solanum tuberosum	38.55	8.00e-45	175.00
IUUC-Sar-112965	Sorex araneus	86.38	0.00e+00	1813.00
IUUC-Sbi-113880	Sorghum bicolor	34.52	3.00e-43	169.00
IUUC-Ssc-115927	Sus scrofa	98.28	0.00e+00	6028.00
IUUC-Tgu-117132	Taeniopygia guttata	92.20	0.00e+00	8178.00
IUUC-Tru-118115	Takifugu rubripes	75.71	0.00e+00	6645.00
IUUC-Tsy-118899	Tarsius syrichta	94.24	0.00e+00	5071.00
IUUC-Tni-120891	Tetraodon nigroviridis	74.66	0.00e+00	6616.00
IUUC-Tae-125407	Triticum aestivum	46.70	2.00e-45	176.00
IUUC-Tur-126479	Triticum urartu	45.86	1.00e-41	164.00
IUUC-Tme-126930	Tuber melanosporum	42.15	5.00e-46	180.00
IUUC-Tbe-127630	Tupaia belangeri	93.62	0.00e+00	1547.00
IUUC-Ttr-128629	Tursiops truncatus	95.87	0.00e+00	8484.00
IUUC-Vpa-130310	Vicugna pacos	97.06	0.00e+00	8381.00
IUUC-Xtr-131861	Xenopus tropicalis	83.70	0.00e+00	7259.00
IUUC-Xma-133613	Xiphophorus maculatus	77.85	0.00e+00	6781.00
IUUC-Zma-135768	Zea mays	35.35	2.00e-43	172.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence