iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098725

Ensembl Protein ID

ENSPPYP00000018045.2

UniProt Accession

H2PHM0; H2PHM0_PONAB

Genbank Protein ID

ENSPPYP00000018045

Protein Name

Sequestosome-1

Genbank Nucleotide ID

ABGA01177642

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000016130.2	ENSPPYT00000018766.2	ENSPPYP00000018045.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	2.00e-18	66.4	22	102

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 3    rvkvsykgeirsfaldlekpgkfedLlkavrt.ltelknsevalkYeDedGDlvtlksDedldkavsllaskksllrlliqkk 84
           r+ +++++e+++ a+++++pg +e+Ll++v++ +++l+   ++ +Y+DedGDlv+++sDe+l++a+s+   k++++r++i++k
   Q: 22   RFSFCFSPEPEAEAEAAAGPGPCERLLSRVAAlFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSY--VKDDIFRIYIKEK 102
           899*****************************999********************************7..9*********975 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MASLTVKAYL LGKEEAAREI RRFSFCFSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP 60
GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAAGAGAG GGGTCAGCAA TGAGGGGGCC GGGAGACCTG GAGCGAGGGG TAGCGGGGAA 60
GGGGAGAGTA GTGAAGGGGC CTCTGCAGGG AGGCTCTCGC GCCGCGACGA CGGTGGCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00666--PB1
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	80.91	2.00e-144	505.00
IUUC-Apl-003897	Anas platyrhynchos	56.34	4.00e-101	361.00
IUUC-Aca-004699	Anolis carolinensis	46.29	2.00e-85	309.00
IUUC-Ame-010982	Astyanax mexicanus	64.60	4.00e-28	119.00
IUUC-Bgr-012289	Blumeria graminis	34.94	9.00e-07	49.30
IUUC-Bta-012634	Bos taurus	82.73	0.00e+00	664.00
IUUC-Bci-013659	Botrytis cinerea	45.61	1.00e-07	52.40
IUUC-Cel-018660	Caenorhabditis elegans	50.00	8.00e-11	59.70
IUUC-Cja-019684	Callithrix jacchus	87.24	0.00e+00	665.00
IUUC-Cfa-020573	Canis familiaris	78.30	1.00e-115	409.00
IUUC-Cpo-021425	Cavia porcellus	75.23	6.00e-157	546.00
IUUC-Csa-023968	Chlorocebus sabaeus	86.82	0.00e+00	664.00
IUUC-Cho-024596	Choloepus hoffmanni	73.25	5.00e-30	124.00
IUUC-Cin-025557	Ciona intestinalis	34.96	5.00e-13	68.20
IUUC-Csv-025974	Ciona savignyi	26.54	6.00e-13	68.20
IUUC-Cme-027152	Cyanidioschyzon merolae	51.52	2.00e-04	41.20
IUUC-Dre-028621	Danio rerio	41.89	8.00e-82	297.00
IUUC-Dno-029060	Dasypus novemcinctus	83.22	0.00e+00	641.00
IUUC-Dor-030547	Dipodomys ordii	87.55	1.00e-132	466.00
IUUC-Dme-031659	Drosophila melanogaster	45.28	4.00e-08	53.10
IUUC-Ete-033201	Echinops telfairi	73.66	7.00e-141	493.00
IUUC-Eca-033456	Equus caballus	83.55	2.00e-168	585.00
IUUC-Eeu-035157	Erinaceus europaeus	77.48	2.00e-149	521.00
IUUC-Fca-035403	Felis catus	82.09	1.00e-178	618.00
IUUC-Fal-036798	Ficedula albicollis	55.15	2.00e-117	415.00
IUUC-Fox-037985	Fusarium oxysporum	42.11	4.00e-07	50.40
IUUC-Fso-038342	Fusarium solani	40.74	8.00e-07	49.70
IUUC-Gmo-039619	Gadus morhua	40.82	5.00e-46	177.00
IUUC-Ggr-039979	Gaeumannomyces graminis	42.86	2.00e-07	51.60
IUUC-Gga-040137	Gallus gallus	54.39	5.00e-117	414.00
IUUC-Gac-042410	Gasterosteus aculeatus	42.21	3.00e-80	292.00
IUUC-Ggo-044690	Gorilla gorilla	87.27	0.00e+00	667.00
IUUC-Hsa-046390	Homo sapiens	87.05	0.00e+00	664.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	87.73	0.00e+00	686.00
IUUC-Lch-049658	Latimeria chalumnae	45.45	6.00e-95	340.00
IUUC-Loc-052589	Lepisosteus oculatus	46.24	4.00e-96	344.00
IUUC-Laf-053746	Loxodonta africana	77.80	2.00e-165	574.00
IUUC-Mcc-055635	Macaca mulatta	88.84	0.00e+00	672.00
IUUC-Meu-056528	Macropus eugenii	57.14	7.00e-70	257.00
IUUC-Mor-057023	Magnaporthe oryzae	44.44	1.00e-07	52.00
IUUC-Mpo-057400	Magnaporthe poae	42.86	2.00e-07	51.60
IUUC-Mga-059458	Meleagris gallopavo	55.53	6.00e-103	367.00
IUUC-Mvi-060347	Microbotryum violaceum	54.05	1.00e-07	52.40
IUUC-Mmr-061539	Microcebus murinus	87.97	2.00e-133	468.00
IUUC-Mdo-063083	Monodelphis domestica	59.56	1.00e-132	466.00
IUUC-Mmu-063589	Mus musculus	81.45	0.00e+00	658.00
IUUC-Mpu-065727	Mustela putorius furo	79.51	9.00e-157	546.00
IUUC-Mlu-067026	Myotis lucifugus	78.13	2.00e-156	544.00
IUUC-Nle-069356	Nomascus leucogenys	62.61	2.00e-105	375.00
IUUC-Opr-071091	Ochotona princeps	72.83	3.00e-95	342.00
IUUC-Ont-071864	Oreochromis niloticus	45.43	6.00e-85	307.00
IUUC-Oan-073308	Ornithorhynchus anatinus	57.99	1.00e-118	419.00
IUUC-Ocu-074110	Oryctolagus cuniculus	82.27	0.00e+00	650.00
IUUC-Ola-086944	Oryzias latipes	42.40	3.00e-24	104.00
IUUC-Olu-087872	Ostreococcus lucimarinus	46.43	6.00e-05	42.70
IUUC-Oga-088869	Otolemur garnettii	81.17	0.00e+00	655.00
IUUC-Oar-089857	Ovis aries	81.33	2.00e-162	565.00
IUUC-Ptr-091640	Pan troglodytes	87.27	0.00e+00	667.00
IUUC-Pan-092831	Papio anubis	85.87	0.00e+00	658.00
IUUC-Psi-093925	Pelodiscus sinensis	54.10	5.00e-112	397.00
IUUC-Pma-094576	Petromyzon marinus	31.35	7.00e-30	124.00
IUUC-Pfo-097297	Poecilia formosa	43.33	8.00e-76	277.00
IUUC-Pca-101106	Procavia capensis	81.36	0.00e+00	627.00
IUUC-Pva-102710	Pteropus vampyrus	83.12	9.00e-169	586.00
IUUC-Rno-105539	Rattus norvegicus	83.26	0.00e+00	660.00
IUUC-Sha-107469	Sarcophilus harrisii	56.25	5.00e-103	367.00
IUUC-Sja-108012	Schizosaccharomyces japonicus	36.96	1.00e-05	43.50
IUUC-Spo-108198	Schizosaccharomyces pombe	50.00	5.00e-06	45.40
IUUC-Ssl-108622	Sclerotinia sclerotiorum	43.86	1.00e-07	52.40
IUUC-Ssc-115526	Sus scrofa	83.41	0.00e+00	642.00
IUUC-Tgu-117194	Taeniopygia guttata	57.22	2.00e-101	362.00
IUUC-Tru-117896	Takifugu rubripes	45.72	1.00e-86	313.00
IUUC-Tni-119943	Tetraodon nigroviridis	44.72	1.00e-76	280.00
IUUC-Tre-122251	Trichoderma reesei	42.86	3.00e-07	50.80
IUUC-Tvi-122314	Trichoderma virens	42.86	3.00e-07	50.80
IUUC-Ttr-128676	Tursiops truncatus	85.91	0.00e+00	658.00
IUUC-Vda-129812	Verticillium dahliae	40.26	8.00e-08	52.40
IUUC-Vpa-130319	Vicugna pacos	96.00	9.00e-57	213.00
IUUC-Xtr-132907	Xenopus tropicalis	50.22	2.00e-110	392.00
IUUC-Xma-133047	Xiphophorus maculatus	46.45	3.00e-79	288.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence