iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pma-094372

Ensembl Protein ID

ENSPMAP00000002090.1

UniProt Accession

S4RA59; S4RA59_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000001847.1	ENSPMAT00000002100.1	ENSPMAP00000002090.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.20e-20	71.1	633	685

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            + y+++a +  eL+l +Gdvv++ +k   ++gW++g  e  g+ G fP+ +ve+
   Q: 633  VARYSFSARDMRELSLSQGDVVKIYSKSGANQGWWRG--EVDGRVGWFPSTYVEE 685
           578**********************************..9*************86 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

QQDKGGMTED DKRNCCAKEI KETEEKYAAT LESIEKNYMG PLRLTLTQLE METIFMNIEE 60
LHRVHRAFVA EIRQSYSLSG GRKFHELFLT FKPRLLIYGR YCSQLEGAHT CINRLLQTRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCAGGACA AGGGGGGCAT GACGGAGGAC GACAAGAGGA ACTGCTGCGC TAAGGAGATA 60
AAGGAGACGG AGGAGAAGTA CGCGGCGACG CTCGAGAGCA TCGAGAAGGT GCCGCTCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001437	Ailuropoda melanoleuca	52.49	0.00e+00	685.00
IUUC-Atr-002599	Amborella trichopoda	30.77	1.20e+00	26.60
IUUC-Apl-003262	Anas platyrhynchos	54.43	0.00e+00	692.00
IUUC-Aca-004477	Anolis carolinensis	50.14	0.00e+00	674.00
IUUC-Acl-008331	Aspergillus clavatus	44.90	1.00e-08	53.10
IUUC-Ame-011608	Astyanax mexicanus	52.73	0.00e+00	721.00
IUUC-Bta-013147	Bos taurus	53.53	0.00e+00	711.00
IUUC-Cel-018578	Caenorhabditis elegans	30.80	1.00e-51	196.00
IUUC-Cja-018877	Callithrix jacchus	50.86	0.00e+00	658.00
IUUC-Cfa-020315	Canis familiaris	51.88	0.00e+00	686.00
IUUC-Cpo-021543	Cavia porcellus	53.60	0.00e+00	708.00
IUUC-Csa-024204	Chlorocebus sabaeus	51.11	0.00e+00	687.00
IUUC-Cin-025115	Ciona intestinalis	33.05	2.00e-95	342.00
IUUC-Csv-025995	Ciona savignyi	34.15	4.00e-102	364.00
IUUC-Dre-028308	Danio rerio	54.47	0.00e+00	752.00
IUUC-Dno-029584	Dasypus novemcinctus	50.29	0.00e+00	644.00
IUUC-Dor-031014	Dipodomys ordii	46.05	2.00e-156	545.00
IUUC-Eca-033448	Equus caballus	52.59	0.00e+00	683.00
IUUC-Eeu-034719	Erinaceus europaeus	39.31	2.00e-108	385.00
IUUC-Fca-035460	Felis catus	51.74	0.00e+00	676.00
IUUC-Fal-036684	Ficedula albicollis	53.29	0.00e+00	686.00
IUUC-Gmo-038816	Gadus morhua	51.59	0.00e+00	665.00
IUUC-Gga-040999	Gallus gallus	53.08	0.00e+00	686.00
IUUC-Gac-041353	Gasterosteus aculeatus	51.30	0.00e+00	678.00
IUUC-Ggo-044558	Gorilla gorilla	52.57	0.00e+00	699.00
IUUC-Hsa-046208	Homo sapiens	52.57	0.00e+00	697.00
IUUC-Itr-047931	Ictidomys tridecemlineatus	53.84	0.00e+00	704.00
IUUC-Lch-049650	Latimeria chalumnae	50.00	7.00e-64	234.00
IUUC-Loc-052827	Lepisosteus oculatus	54.03	0.00e+00	761.00
IUUC-Laf-054009	Loxodonta africana	51.01	0.00e+00	663.00
IUUC-Mcc-055054	Macaca mulatta	52.43	0.00e+00	694.00
IUUC-Meu-056680	Macropus eugenii	45.70	8.00e-168	582.00
IUUC-Mga-060106	Meleagris gallopavo	54.14	0.00e+00	692.00
IUUC-Mmr-061118	Microcebus murinus	53.24	0.00e+00	697.00
IUUC-Mdo-062380	Monodelphis domestica	51.20	0.00e+00	683.00
IUUC-Mmu-063135	Mus musculus	53.74	0.00e+00	716.00
IUUC-Mpu-066135	Mustela putorius furo	50.79	0.00e+00	673.00
IUUC-Mlu-068108	Myotis lucifugus	50.65	1.00e-178	619.00
IUUC-Nle-069863	Nomascus leucogenys	51.71	0.00e+00	682.00
IUUC-Opr-070372	Ochotona princeps	42.67	5.00e-100	357.00
IUUC-Ont-071945	Oreochromis niloticus	52.95	0.00e+00	709.00
IUUC-Oan-073384	Ornithorhynchus anatinus	53.67	0.00e+00	701.00
IUUC-Ocu-074194	Oryctolagus cuniculus	50.07	0.00e+00	639.00
IUUC-Obr-076390	Oryza brachyantha	44.00	6.00e-07	47.00
IUUC-Ome-081119	Oryza meridionalis	32.76	7.50e-01	26.90
IUUC-Ola-087499	Oryzias latipes	51.88	0.00e+00	679.00
IUUC-Oga-088444	Otolemur garnettii	51.37	0.00e+00	673.00
IUUC-Oar-089576	Ovis aries	50.85	0.00e+00	648.00
IUUC-Ptr-090507	Pan troglodytes	52.87	0.00e+00	703.00
IUUC-Pan-092550	Papio anubis	51.65	0.00e+00	692.00
IUUC-Psi-094021	Pelodiscus sinensis	53.17	0.00e+00	681.00
IUUC-Pfo-096732	Poecilia formosa	54.89	0.00e+00	735.00
IUUC-Pab-098698	Pongo abelii	47.78	0.00e+00	628.00
IUUC-Pca-100295	Procavia capensis	53.08	0.00e+00	709.00
IUUC-Pva-102262	Pteropus vampyrus	48.76	8.00e-174	602.00
IUUC-Rno-105332	Rattus norvegicus	53.11	0.00e+00	693.00
IUUC-Sha-106529	Sarcophilus harrisii	53.23	0.00e+00	717.00
IUUC-Sar-113456	Sorex araneus	47.64	0.00e+00	626.00
IUUC-Ssc-116176	Sus scrofa	52.77	0.00e+00	691.00
IUUC-Tgu-116917	Taeniopygia guttata	54.51	0.00e+00	693.00
IUUC-Tru-118577	Takifugu rubripes	51.15	0.00e+00	682.00
IUUC-Tsy-119429	Tarsius syrichta	50.13	5.00e-101	360.00
IUUC-Tni-120819	Tetraodon nigroviridis	53.67	0.00e+00	721.00
IUUC-Tbe-127235	Tupaia belangeri	37.32	6.00e-59	220.00
IUUC-Ttr-128281	Tursiops truncatus	50.36	0.00e+00	647.00
IUUC-Vpa-130066	Vicugna pacos	36.81	5.00e-23	101.00
IUUC-Xtr-132747	Xenopus tropicalis	49.28	0.00e+00	642.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence