iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044524

Ensembl Protein ID

ENSGGOP00000019953.1

UniProt Accession

G3RVX3; G3RVX3_GORGO

Protein Name

Uncharacterized protein

Gene Name

KDM5A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000004563.2	ENSGGOT00000026723.1	ENSGGOP00000019953.1
ENSGGOG00000004563.2	ENSGGOT00000004596.2	ENSGGOP00000004481.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.10e-18	66.7	174	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           vC +Cg+g +++ +l+ C+ C++ +H  Cl ++  +++p+ + w CpkC +
   Q: 174  VCMFCGRGNNED-KLLLCDGCDDSYHTFCLIPP-LPDVPKGD-WRCPKCVA 221
           8*********88.6*******************.*******7.******75 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

QIVASKGGFE MVTKEKKWSK VGSRLGYLPG KGTGSLLKSH YERILYPYEL FQSGVSLMGV 60
QMPNLDLKEK VEPEVLSTDT QTSPEPGTRM NILPKRTRRV KSQSESGDVS RNTELKKLQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCAGATTGT TGCCAGCAAA GGAGGTTTTG AAATGGTCAC CAAAGAGAAG AAATGGTCTA 60
AAGTGGGTAG TCGCTTGGGA TATCTGCCAG GAAAAGGAAC TGGGTCTCTA TTGAAGTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002061	Ailuropoda melanoleuca	91.85	0.00e+00	2504.00
IUUC-Atr-002595	Amborella trichopoda	29.93	3.00e-104	374.00
IUUC-Apl-004141	Anas platyrhynchos	85.82	0.00e+00	2429.00
IUUC-Aca-004952	Anolis carolinensis	84.12	0.00e+00	2350.00
IUUC-Ani-009139	Aspergillus nidulans	33.55	4.00e-107	383.00
IUUC-Ate-010453	Aspergillus terreus	29.47	9.00e-116	412.00
IUUC-Ame-011323	Astyanax mexicanus	79.06	0.00e+00	1742.00
IUUC-Bgr-012241	Blumeria graminis	29.37	3.00e-106	380.00
IUUC-Bta-012902	Bos taurus	90.78	0.00e+00	2499.00
IUUC-Cja-018988	Callithrix jacchus	90.39	0.00e+00	2523.00
IUUC-Cfa-020212	Canis familiaris	90.72	0.00e+00	2462.00
IUUC-Cpo-022221	Cavia porcellus	89.29	0.00e+00	1811.00
IUUC-Csa-023575	Chlorocebus sabaeus	92.41	0.00e+00	2426.00
IUUC-Cho-024280	Choloepus hoffmanni	85.73	0.00e+00	2256.00
IUUC-Cin-025321	Ciona intestinalis	49.15	0.00e+00	1073.00
IUUC-Dre-027909	Danio rerio	76.36	0.00e+00	1571.00
IUUC-Dno-029473	Dasypus novemcinctus	90.82	0.00e+00	2372.00
IUUC-Eca-034265	Equus caballus	91.15	0.00e+00	2508.00
IUUC-Fca-035476	Felis catus	90.64	0.00e+00	2494.00
IUUC-Fal-037078	Ficedula albicollis	91.77	0.00e+00	2185.00
IUUC-Ggr-039929	Gaeumannomyces graminis	30.23	2.00e-108	388.00
IUUC-Gga-040466	Gallus gallus	84.87	0.00e+00	2413.00
IUUC-Gac-042566	Gasterosteus aculeatus	75.10	0.00e+00	1759.00
IUUC-Gma-044327	Glycine max	31.48	5.00e-92	333.00
IUUC-Hsa-045821	Homo sapiens	92.99	0.00e+00	2555.00
IUUC-Kpa-049245	Komagataella pastoris	22.58	9.00e-27	116.00
IUUC-Lch-050630	Latimeria chalumnae	73.78	0.00e+00	1717.00
IUUC-Loc-051963	Lepisosteus oculatus	77.77	0.00e+00	1789.00
IUUC-Laf-053918	Loxodonta africana	83.61	0.00e+00	2117.00
IUUC-Mcc-055672	Macaca mulatta	91.21	0.00e+00	2528.00
IUUC-Meu-056374	Macropus eugenii	77.96	0.00e+00	1297.00
IUUC-Mor-057198	Magnaporthe oryzae	30.70	4.00e-119	423.00
IUUC-Mga-059192	Meleagris gallopavo	76.32	0.00e+00	2056.00
IUUC-Mmr-060968	Microcebus murinus	89.77	0.00e+00	2499.00
IUUC-Mdo-062945	Monodelphis domestica	88.56	0.00e+00	2333.00
IUUC-Mmu-063614	Mus musculus	89.87	0.00e+00	2473.00
IUUC-Mpu-066349	Mustela putorius furo	91.35	0.00e+00	2402.00
IUUC-Mlu-067363	Myotis lucifugus	91.34	0.00e+00	2558.00
IUUC-Nle-070142	Nomascus leucogenys	92.74	0.00e+00	2549.00
IUUC-Opr-071002	Ochotona princeps	97.58	0.00e+00	1254.00
IUUC-Ont-072471	Oreochromis niloticus	78.19	0.00e+00	1700.00
IUUC-Oan-072797	Ornithorhynchus anatinus	77.98	0.00e+00	1799.00
IUUC-Ocu-074164	Oryctolagus cuniculus	90.20	0.00e+00	2528.00
IUUC-Ome-081764	Oryza meridionalis	31.26	7.00e-89	323.00
IUUC-Ola-087076	Oryzias latipes	74.32	0.00e+00	1739.00
IUUC-Oga-088350	Otolemur garnettii	91.66	0.00e+00	2521.00
IUUC-Oar-090045	Ovis aries	90.72	0.00e+00	2501.00
IUUC-Ptr-091199	Pan troglodytes	92.48	0.00e+00	2543.00
IUUC-Pan-092094	Papio anubis	87.69	0.00e+00	2270.00
IUUC-Psi-093550	Pelodiscus sinensis	84.43	0.00e+00	2158.00
IUUC-Ppa-095839	Physcomitrella patens	35.20	5.00e-16	81.30
IUUC-Pfo-097266	Poecilia formosa	74.20	0.00e+00	1746.00
IUUC-Pab-098576	Pongo abelii	92.93	0.00e+00	2547.00
IUUC-Pca-100123	Procavia capensis	93.74	0.00e+00	1423.00
IUUC-Pva-103109	Pteropus vampyrus	85.22	0.00e+00	2321.00
IUUC-Pte-104195	Pyrenophora teres	30.05	8.00e-122	432.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	30.14	2.00e-123	437.00
IUUC-Rno-105664	Rattus norvegicus	89.75	0.00e+00	2469.00
IUUC-Sce-106207	Saccharomyces cerevisiae	35.04	1.00e-72	268.00
IUUC-Sha-107506	Sarcophilus harrisii	86.95	0.00e+00	2299.00
IUUC-Sja-107734	Schizosaccharomyces japonicus	21.17	2.00e-34	142.00
IUUC-Spo-108283	Schizosaccharomyces pombe	23.73	2.00e-51	198.00
IUUC-Smo-108843	Selaginella moellendorffii	52.08	1.00e-10	62.40
IUUC-Sit-110534	Setaria italica	31.70	5.00e-103	370.00
IUUC-Sly-111298	Solanum lycopersicum	31.82	7.00e-102	366.00
IUUC-Sar-113052	Sorex araneus	90.25	0.00e+00	2494.00
IUUC-Sbi-114173	Sorghum bicolor	58.14	7.00e-12	64.70
IUUC-Tgu-116613	Taeniopygia guttata	84.67	0.00e+00	2363.00
IUUC-Tru-118604	Takifugu rubripes	74.52	0.00e+00	1793.00
IUUC-Tsy-119237	Tarsius syrichta	98.58	0.00e+00	1223.00
IUUC-Tni-120779	Tetraodon nigroviridis	74.18	0.00e+00	1766.00
IUUC-Tvi-122263	Trichoderma virens	29.29	1.00e-108	389.00
IUUC-Tme-127087	Tuber melanosporum	30.84	1.00e-129	458.00
IUUC-Tbe-127627	Tupaia belangeri	98.74	0.00e+00	803.00
IUUC-Ttr-129242	Tursiops truncatus	89.95	0.00e+00	2460.00
IUUC-Vda-129733	Verticillium dahliae	29.85	1.00e-104	375.00
IUUC-Vpa-130429	Vicugna pacos	89.60	0.00e+00	1330.00
IUUC-Xtr-131762	Xenopus tropicalis	77.72	0.00e+00	1950.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence