iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000016058.1	ENSAMET00000017643.1	ENSAMEP00000016947.1
ENSAMEG00000016058.1	ENSAMET00000017646.1	ENSAMEP00000016950.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-08	35.0	14	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iC+e +k+  ++++CgH+f++ Cl q++   k s+s+   CPlCr
   Q: 14   CPICQELPKE-AVSTDCGHLFCRGCLaQHV--AKASASGVPCCPLCR 57
           ********99.999************9999..8888**********8 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAPLWEDGQG EGVCPICQEL PKEAVSTDCG HLFCRGCLAQ HVAKASASGV PCCPLCRKPC 60
SEGVLGVAHL CPRHQQKVFY FCEESRRLLC VQCLGSPEHQ GHHELTLESA VSHYKERLGR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCCCTC TGTGGGAGGA CGGCCAGGGG GAGGGCGTCT GCCCCATCTG CCAGGAGCTG 60
CCGAAAGAGG CCGTGAGCAC GGACTGCGGA CACCTCTTCT GTCGAGGGTG CCTGGCTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000315--Znf_B-box
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF00097--zf-C3HC4

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0008385--C:IkappaB kinase complex
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042177--P:negative regulation of protein catabolic process
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-012543	Bos taurus	56.31	2.00e-51	195.00
IUUC-Cja-018793	Callithrix jacchus	49.80	9.00e-48	183.00
IUUC-Csa-023101	Chlorocebus sabaeus	55.56	5.00e-60	223.00
IUUC-Cho-024926	Choloepus hoffmanni	60.56	9.00e-21	93.60
IUUC-Dno-029338	Dasypus novemcinctus	42.73	3.00e-30	125.00
IUUC-Dor-030164	Dipodomys ordii	53.10	2.00e-45	175.00
IUUC-Dse-031337	Dothistroma septosporum	30.59	4.00e-07	49.30
IUUC-Ete-032446	Echinops telfairi	39.84	3.00e-35	141.00
IUUC-Eca-034042	Equus caballus	60.85	3.00e-59	221.00
IUUC-Eeu-034444	Erinaceus europaeus	45.49	2.00e-44	172.00
IUUC-Ggo-044410	Gorilla gorilla	60.39	3.00e-61	228.00
IUUC-Hsa-045978	Homo sapiens	60.82	1.00e-59	222.00
IUUC-Itr-048126	Ictidomys tridecemlineatus	51.46	7.00e-50	190.00
IUUC-Laf-054019	Loxodonta africana	45.02	2.00e-38	152.00
IUUC-Mcc-054616	Macaca mulatta	60.63	2.00e-67	248.00
IUUC-Meu-055981	Macropus eugenii	35.89	2.00e-30	125.00
IUUC-Mdo-062958	Monodelphis domestica	37.29	4.00e-32	131.00
IUUC-Mmu-063571	Mus musculus	50.21	7.00e-47	180.00
IUUC-Opr-071083	Ochotona princeps	55.16	7.00e-59	220.00
IUUC-Ocu-073939	Oryctolagus cuniculus	57.03	3.00e-58	218.00
IUUC-Oga-088040	Otolemur garnettii	55.64	9.00e-56	209.00
IUUC-Oar-089914	Ovis aries	55.20	2.00e-59	222.00
IUUC-Ptr-091240	Pan troglodytes	54.32	3.00e-56	211.00
IUUC-Pan-092095	Papio anubis	63.51	2.00e-62	231.00
IUUC-Pab-098406	Pongo abelii	60.63	2.00e-62	232.00
IUUC-Pca-101043	Procavia capensis	51.75	1.00e-45	176.00
IUUC-Pva-102651	Pteropus vampyrus	58.20	7.00e-62	229.00
IUUC-Rno-106090	Rattus norvegicus	48.56	4.00e-45	174.00
IUUC-Smo-109224	Selaginella moellendorffii	48.94	1.00e-05	44.70
IUUC-Ssc-115942	Sus scrofa	57.14	9.00e-60	223.00
IUUC-Tsy-119497	Tarsius syrichta	58.57	1.00e-64	239.00
IUUC-Tbe-127279	Tupaia belangeri	53.66	3.00e-47	181.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence