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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063516
UUCD1 version UUC-MuM-00488
Ensembl Protein ID ENSMUSP00000034060.5
UniProt Accession E9QQ33; E9QQ33_MOUSE
Genbank Protein ID ENSMUSP00000034060
Protein Name E3 ubiquitin-protein ligase SH3RF1
Genbank Nucleotide ID AC117196
Gene Name Sh3rf1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000031642.9 ENSMUST00000034060.6 ENSMUSP00000034060.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 1.20e-07 33.2 12 53
UBD/SH3 2.30e-47 159.9 455 510
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +      s++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VGSRNELRCPECR 53
           **********9**************9777....899*********8 PP
   

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +  ++y+y++ ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+v+ +
   Q: 455  VYVAIYPYTPRKEDELELRKGEMFLVF-ERC-QDGWYKGTSMHTSKIGVFPGNYVAPV 510
           5679**********************9.555.569********************988 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VGSRNELRCP ECRTLVGSGV 60
DELPSNILLV RLLDGIKQRP WKPGPGGGGG TTCTNTLRAQ GSTVVNCGSK DLQSSQCGQQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063516|E3,RING;UBD,SH3|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGGCAGGGC GCCCTTGCCC CAGCCTCTTC CTGGTCCCTC GGCGCCACTC CCACCGCCCT 60
CCTCCTGGGT AGCCCAAATT TGCTCGGGGT GCACGTCCTC GGGGCGTGAA GGCGCGGGTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063516|E3,RING;UBD,SH3|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4
PRINTS

PR00452--SH3DOMAIN
SMART

SM00184--RING
SM00326--SH3
Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade
KEGG mmu:59009
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001528 Ailuropoda melanoleuca 86.59 0.00e+00 1303.00
IUUC-Apl-003961 Anas platyrhynchos 79.04 0.00e+00 1194.00
IUUC-Aca-004386 Anolis carolinensis 75.75 0.00e+00 1177.00
IUUC-Ame-010659 Astyanax mexicanus 73.80 5.00e-150 525.00
IUUC-Bta-012563 Bos taurus 66.00 5.00e-128 451.00
IUUC-Cja-019730 Callithrix jacchus 89.05 0.00e+00 1313.00
IUUC-Cfa-020992 Canis familiaris 86.69 0.00e+00 1357.00
IUUC-Cpo-021304 Cavia porcellus 88.93 0.00e+00 1407.00
IUUC-Csa-023925 Chlorocebus sabaeus 89.15 0.00e+00 1311.00
IUUC-Cho-024630 Choloepus hoffmanni 81.44 0.00e+00 880.00
IUUC-Cin-025274 Ciona intestinalis 46.25 4.00e-71 261.00
IUUC-Cme-027278 Cyanidioschyzon merolae 44.19 4.00e-07 50.40
IUUC-Dre-028290 Danio rerio 59.76 0.00e+00 907.00
IUUC-Dno-029083 Dasypus novemcinctus 84.80 0.00e+00 1236.00
IUUC-Dor-030388 Dipodomys ordii 91.57 0.00e+00 646.00
IUUC-Dme-032207 Drosophila melanogaster 43.66 2.00e-63 237.00
IUUC-Ete-032809 Echinops telfairi 82.37 6.00e-133 468.00
IUUC-Eca-034185 Equus caballus 87.19 0.00e+00 1120.00
IUUC-Eeu-034816 Erinaceus europaeus 77.40 0.00e+00 1140.00
IUUC-Fca-036439 Felis catus 87.18 0.00e+00 1379.00
IUUC-Fal-037074 Ficedula albicollis 77.35 0.00e+00 1164.00
IUUC-Gmo-039443 Gadus morhua 67.95 8.00e-93 335.00
IUUC-Gga-040749 Gallus gallus 77.52 0.00e+00 1121.00
IUUC-Gac-041420 Gasterosteus aculeatus 73.57 1.00e-145 510.00
IUUC-Ggo-045215 Gorilla gorilla 89.37 0.00e+00 1360.00
IUUC-Hsa-046315 Homo sapiens 89.49 0.00e+00 1354.00
IUUC-Itr-048265 Ictidomys tridecemlineatus 86.53 4.00e-153 534.00
IUUC-Lch-049453 Latimeria chalumnae 69.66 0.00e+00 911.00
IUUC-Loc-052248 Lepisosteus oculatus 40.24 2.00e-79 290.00
IUUC-Laf-053651 Loxodonta africana 87.28 0.00e+00 1315.00
IUUC-Mcc-054688 Macaca mulatta 89.37 0.00e+00 1343.00
IUUC-Meu-056291 Macropus eugenii 72.79 0.00e+00 784.00
IUUC-Mga-059944 Meleagris gallopavo 77.13 0.00e+00 1154.00
IUUC-Mmr-061553 Microcebus murinus 86.02 0.00e+00 1235.00
IUUC-Mdo-062313 Monodelphis domestica 77.21 0.00e+00 1186.00
IUUC-Mpu-066064 Mustela putorius furo 86.88 0.00e+00 1325.00
IUUC-Mlu-067312 Myotis lucifugus 83.92 0.00e+00 1235.00
IUUC-Nle-069035 Nomascus leucogenys 89.15 0.00e+00 1357.00
IUUC-Opr-070690 Ochotona princeps 86.40 0.00e+00 664.00
IUUC-Ont-071484 Oreochromis niloticus 58.32 0.00e+00 863.00
IUUC-Oan-073305 Ornithorhynchus anatinus 80.27 0.00e+00 1227.00
IUUC-Ocu-074936 Oryctolagus cuniculus 88.39 0.00e+00 1349.00
IUUC-Ola-086675 Oryzias latipes 59.17 8.00e-174 604.00
IUUC-Oga-087933 Otolemur garnettii 79.43 0.00e+00 1022.00
IUUC-Oar-090408 Ovis aries 65.42 2.00e-112 400.00
IUUC-Ptr-090865 Pan troglodytes 89.60 0.00e+00 1357.00
IUUC-Pan-092362 Papio anubis 89.04 0.00e+00 1310.00
IUUC-Psi-093876 Pelodiscus sinensis 78.05 0.00e+00 1192.00
IUUC-Pfo-097116 Poecilia formosa 59.73 0.00e+00 863.00
IUUC-Pab-098127 Pongo abelii 89.37 0.00e+00 1357.00
IUUC-Pca-100485 Procavia capensis 94.40 0.00e+00 692.00
IUUC-Pva-102661 Pteropus vampyrus 84.64 0.00e+00 1239.00
IUUC-Rno-105728 Rattus norvegicus 93.62 0.00e+00 1469.00
IUUC-Sha-106515 Sarcophilus harrisii 83.64 0.00e+00 848.00
IUUC-Sar-113161 Sorex araneus 92.13 0.00e+00 634.00
IUUC-Ssc-115314 Sus scrofa 88.77 0.00e+00 643.00
IUUC-Tgu-117012 Taeniopygia guttata 78.70 0.00e+00 1176.00
IUUC-Tru-118467 Takifugu rubripes 60.91 1.00e-161 564.00
IUUC-Tsy-119566 Tarsius syrichta 81.01 6.00e-174 604.00
IUUC-Tni-120830 Tetraodon nigroviridis 56.63 1.00e-165 577.00
IUUC-Tbe-128070 Tupaia belangeri 94.15 0.00e+00 696.00
IUUC-Ttr-128161 Tursiops truncatus 91.76 2.00e-133 469.00
IUUC-Xtr-132628 Xenopus tropicalis 72.72 0.00e+00 1074.00
Created Date 25-Jun-2017

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