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Tag Content
iUUCD ID IUUC-Fal-036783
Ensembl Protein ID ENSFALP00000003432.1
UniProt Accession U3JKX8; U3JKX8_FICAL
Genbank Protein ID ENSFALP00000003432
Protein Name Uncharacterized protein
Genbank Nucleotide ID AGTO01021574
Gene Name FBXW11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFALG00000003280.1 ENSFALT00000003446.1 ENSFALP00000003432.1
ENSFALG00000003280.1 ENSFALT00000003454.1 ENSFALP00000003440.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.90e-58 191.5 430 464
UBD/Beta-Prp 6.30e-69 232.1 344 508
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ v+c++f d +++vsG++Dg+ikvWDl    +
   Q: 430  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLQAALD 464
           8**********.44****************977665 PP
   

   UBD/Beta-Prp
   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ +
   Q: 344  LRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR-V 427
           445569*************9..8**************************************..************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           l+gh+++v+c++++   + +vsG++D+++++Wdl         ++  +lrtl + h ++v  l+fd+  ++++s s+d t+ +wd+
   Q: 428  LEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLqaaldprapASTLCLRTLVE-HSGRVFRLQFDE--FQIISSSHDDTILIWDF 508
           **************9..***********************************99.************..99**************7 PP
   
Organism Ficedula albicollis
Protein Sequence
(Fasta)
MCALRCLQSM PSVRCLQNTS VMEDQNEDES PKKNTLWQIS NGTSSVIVSR KRPSEGNYEK 60
EKDLCIKYFD QWSESDQVEF VEHLISRMCH YQHGHINSYL KPMLQRDFIT ALPEQGLDHI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Fal-036783|E3,WD_repeat;UBD,Beta-Prp|Ficedula albicollis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGTTCTGTGC CAAGGTCTTT GTGGCTAGGC TGCTCCAACC TGGTAGAGAG CATGTGCGCA 60
CTGAGATGCC TGCAGAGCAT GCCCAGTGTC AGATGTCTCC AGGTGCCTTT CTTCTTTCTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Fal-036783|E3,WD_repeat;UBD,Beta-Prp|Ficedula albicollis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
KEGG fab:101812846
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001397 Ailuropoda melanoleuca 95.48 0.00e+00 1038.00
IUUC-Apl-003449 Anas platyrhynchos 99.81 0.00e+00 1094.00
IUUC-Ame-011393 Astyanax mexicanus 90.50 0.00e+00 967.00
IUUC-Bta-012920 Bos taurus 98.46 0.00e+00 1061.00
IUUC-Cel-018392 Caenorhabditis elegans 63.36 0.00e+00 638.00
IUUC-Cja-018879 Callithrix jacchus 95.48 0.00e+00 1038.00
IUUC-Cfa-020021 Canis familiaris 95.48 0.00e+00 1038.00
IUUC-Cpo-022151 Cavia porcellus 99.22 0.00e+00 1052.00
IUUC-Csa-024095 Chlorocebus sabaeus 99.61 0.00e+00 1053.00
IUUC-Cho-024658 Choloepus hoffmanni 90.48 8.00e-132 463.00
IUUC-Dre-028160 Danio rerio 90.58 0.00e+00 966.00
IUUC-Dno-029485 Dasypus novemcinctus 89.00 0.00e+00 928.00
IUUC-Dor-030498 Dipodomys ordii 95.10 0.00e+00 1031.00
IUUC-Dse-031287 Dothistroma septosporum 29.19 1.00e-52 201.00
IUUC-Eca-033804 Equus caballus 95.59 0.00e+00 1020.00
IUUC-Fca-035887 Felis catus 99.42 0.00e+00 1063.00
IUUC-Gmo-038590 Gadus morhua 87.01 0.00e+00 942.00
IUUC-Gga-040628 Gallus gallus 99.62 0.00e+00 1095.00
IUUC-Gac-041305 Gasterosteus aculeatus 87.01 0.00e+00 946.00
IUUC-Ggo-044604 Gorilla gorilla 95.48 0.00e+00 1038.00
IUUC-Hsa-046139 Homo sapiens 95.48 0.00e+00 1038.00
IUUC-Lch-050460 Latimeria chalumnae 97.28 0.00e+00 1038.00
IUUC-Laf-053968 Loxodonta africana 99.44 0.00e+00 1093.00
IUUC-Mcc-055822 Macaca mulatta 96.34 0.00e+00 1082.00
IUUC-Mga-059225 Meleagris gallopavo 99.42 0.00e+00 1052.00
IUUC-Mvi-060284 Microbotryum violaceum 44.95 2.00e-69 256.00
IUUC-Mmr-060746 Microcebus murinus 95.48 0.00e+00 1038.00
IUUC-Mdo-062005 Monodelphis domestica 99.41 0.00e+00 1053.00
IUUC-Mmu-063851 Mus musculus 98.68 0.00e+00 1087.00
IUUC-Mpu-065716 Mustela putorius furo 98.84 0.00e+00 1058.00
IUUC-Mlu-067001 Myotis lucifugus 99.61 0.00e+00 1053.00
IUUC-Nle-069788 Nomascus leucogenys 96.12 0.00e+00 1017.00
IUUC-Opr-071229 Ochotona princeps 95.29 0.00e+00 1036.00
IUUC-Ont-071792 Oreochromis niloticus 87.57 0.00e+00 956.00
IUUC-Oan-072782 Ornithorhynchus anatinus 100.00 0.00e+00 1099.00
IUUC-Ocu-074894 Oryctolagus cuniculus 99.44 0.00e+00 1093.00
IUUC-Ola-086985 Oryzias latipes 89.70 0.00e+00 986.00
IUUC-Oga-088604 Otolemur garnettii 93.12 0.00e+00 1043.00
IUUC-Oar-090412 Ovis aries 99.44 0.00e+00 1095.00
IUUC-Ptr-091039 Pan troglodytes 95.29 0.00e+00 1036.00
IUUC-Pan-092770 Papio anubis 99.41 0.00e+00 1046.00
IUUC-Psi-093887 Pelodiscus sinensis 99.25 0.00e+00 1090.00
IUUC-Pno-094808 Phaeosphaeria nodorum 29.50 3.00e-45 176.00
IUUC-Pfo-096783 Poecilia formosa 89.89 0.00e+00 985.00
IUUC-Pva-102547 Pteropus vampyrus 95.29 0.00e+00 1031.00
IUUC-Rno-105246 Rattus norvegicus 98.68 0.00e+00 1088.00
IUUC-Sha-107339 Sarcophilus harrisii 99.41 0.00e+00 1053.00
IUUC-Sja-107743 Schizosaccharomyces japonicus 35.32 5.00e-74 271.00
IUUC-Spo-108200 Schizosaccharomyces pombe 32.49 3.00e-67 249.00
IUUC-Tgu-116541 Taeniopygia guttata 99.81 0.00e+00 1095.00
IUUC-Tru-117671 Takifugu rubripes 89.14 0.00e+00 978.00
IUUC-Tni-120359 Tetraodon nigroviridis 90.15 0.00e+00 957.00
IUUC-Tbe-127418 Tupaia belangeri 89.27 0.00e+00 951.00
IUUC-Ttr-129131 Tursiops truncatus 95.48 0.00e+00 1037.00
IUUC-Vpa-130668 Vicugna pacos 95.48 0.00e+00 1038.00
IUUC-Xma-133187 Xiphophorus maculatus 95.71 6.00e-159 552.00
Created Date 25-Jun-2017

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