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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046199
UUCD1 version UUC-HoS-00989
Ensembl Protein ID ENSP00000347193.2
UniProt Accession J3KNY7; J3KNY7_HUMAN
Genbank Protein ID EAW65795.1
Protein Name BTB (POZ) domain containing 5, isoform CRA_d; Kelch-like protein 28
Genbank Nucleotide ID AL049870
Gene Name KLHL28; BTBD5; hCG_20873
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000179454.13 ENST00000355081.3 ENSP00000347193.2
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICHPM
DNA & RNA Element
UTRdbcircBasecircRNADbCircNet
miRTarBasemicroRNATRANSFACRepTar
miRNAMapSomamiRmiRcodeRAID2
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
CPLMBioGRID
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB 8.30e-18 66.2 49 112
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box 2.00e-12 46.1 148 179
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D+il vg+++++ahk+vLa+ S++F+a+f+++l+e++ +++ve++ ++ ++++a++++ Ytg++
   Q: 49   CDIILRVGDVKIHAHKVVLASVSPYFKAMFTGNLSEKE-NSEVEFQCIDETALQAIVEYAYTGTV 112
           8***********************************97.************************87 PP
   

   E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box
   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nc+gi rfA++y+c+dL++aa ++i+++F+
   Q: 148  PGNCIGISRFAETYGCRDLYLAATKYICQNFE 179
           56*****************************5 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MHFKCKYSYP ALYQMDHTSP TYMLANLTHL HSEQLLQGLN LLRQHHELCD IILRVGDVKI 60
HAHKVVLASV SPYFKAMFTG NLSEKENSEV EFQCIDETAL QAIVEYAYTG TVFISQDTVE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046199|E3,BTB_3-box|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAAATTTTTT CCCTAGTGTT CCAGAGAGCT ACCAAAGTGC TTTCTGTGAG GAAGTCCCAT 60
GGTCTGGTTT ATATCTTAAC AGCATCAATG GCTGTTATAT GAGATGGAGT AATAATGCAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046199|E3,BTB_3-box|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030569--KLHL28
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001581 Ailuropoda melanoleuca 98.95 0.00e+00 1190.00
IUUC-Apl-003577 Anas platyrhynchos 92.61 0.00e+00 1088.00
IUUC-Aca-004320 Anolis carolinensis 86.56 0.00e+00 924.00
IUUC-Ame-011433 Astyanax mexicanus 84.41 0.00e+00 986.00
IUUC-Bta-012650 Bos taurus 99.12 0.00e+00 1190.00
IUUC-Cja-019878 Callithrix jacchus 99.13 0.00e+00 1192.00
IUUC-Cfa-020936 Canis familiaris 99.12 0.00e+00 1190.00
IUUC-Cpo-022212 Cavia porcellus 97.55 0.00e+00 1176.00
IUUC-Csa-023372 Chlorocebus sabaeus 99.47 0.00e+00 1192.00
IUUC-Cho-024885 Choloepus hoffmanni 97.99 2.00e-173 602.00
IUUC-Dno-029895 Dasypus novemcinctus 97.55 0.00e+00 1174.00
IUUC-Ete-032703 Echinops telfairi 97.99 0.00e+00 917.00
IUUC-Eca-034150 Equus caballus 98.95 0.00e+00 1188.00
IUUC-Eeu-035233 Erinaceus europaeus 96.50 0.00e+00 1164.00
IUUC-Fca-036445 Felis catus 98.77 0.00e+00 1185.00
IUUC-Fal-037156 Ficedula albicollis 82.14 0.00e+00 997.00
IUUC-Gmo-039158 Gadus morhua 84.41 0.00e+00 1016.00
IUUC-Gga-040855 Gallus gallus 91.42 0.00e+00 1121.00
IUUC-Gac-041294 Gasterosteus aculeatus 83.71 0.00e+00 1007.00
IUUC-Ggo-045399 Gorilla gorilla 100.00 0.00e+00 1228.00
IUUC-Itr-048859 Ictidomys tridecemlineatus 98.77 0.00e+00 1182.00
IUUC-Lch-049445 Latimeria chalumnae 88.14 0.00e+00 814.00
IUUC-Loc-052737 Lepisosteus oculatus 85.99 0.00e+00 1012.00
IUUC-Laf-054173 Loxodonta africana 98.25 0.00e+00 1177.00
IUUC-Mcc-055000 Macaca mulatta 99.32 0.00e+00 1221.00
IUUC-Meu-056028 Macropus eugenii 86.05 8.00e-145 507.00
IUUC-Mga-059609 Meleagris gallopavo 92.35 0.00e+00 1119.00
IUUC-Mmr-060842 Microcebus murinus 98.46 0.00e+00 1203.00
IUUC-Mdo-062776 Monodelphis domestica 92.66 0.00e+00 1088.00
IUUC-Mmu-063720 Mus musculus 97.02 0.00e+00 1172.00
IUUC-Mpu-066594 Mustela putorius furo 68.28 0.00e+00 731.00
IUUC-Mlu-067403 Myotis lucifugus 97.02 0.00e+00 1165.00
IUUC-Nle-069242 Nomascus leucogenys 99.30 0.00e+00 1190.00
IUUC-Opr-070942 Ochotona princeps 96.79 9.00e-180 622.00
IUUC-Ont-072586 Oreochromis niloticus 84.62 0.00e+00 1017.00
IUUC-Oan-073070 Ornithorhynchus anatinus 93.24 0.00e+00 1081.00
IUUC-Ocu-074536 Oryctolagus cuniculus 97.60 0.00e+00 1199.00
IUUC-Ola-086669 Oryzias latipes 70.98 0.00e+00 818.00
IUUC-Oga-088974 Otolemur garnettii 98.95 0.00e+00 1187.00
IUUC-Oar-089544 Ovis aries 98.78 0.00e+00 1191.00
IUUC-Ptr-091478 Pan troglodytes 99.66 0.00e+00 1219.00
IUUC-Pan-092653 Papio anubis 99.65 0.00e+00 1192.00
IUUC-Psi-094014 Pelodiscus sinensis 93.35 0.00e+00 1130.00
IUUC-Pfo-097316 Poecilia formosa 83.13 0.00e+00 1013.00
IUUC-Pab-098609 Pongo abelii 99.83 0.00e+00 1226.00
IUUC-Pva-102527 Pteropus vampyrus 96.81 4.00e-180 624.00
IUUC-Rno-105188 Rattus norvegicus 97.55 0.00e+00 1175.00
IUUC-Sha-106543 Sarcophilus harrisii 93.18 0.00e+00 1095.00
IUUC-Sar-113507 Sorex araneus 96.15 0.00e+00 1162.00
IUUC-Ssc-115803 Sus scrofa 98.77 0.00e+00 1185.00
IUUC-Tgu-116661 Taeniopygia guttata 81.75 0.00e+00 912.00
IUUC-Tru-118738 Takifugu rubripes 81.46 0.00e+00 984.00
IUUC-Tsy-119570 Tarsius syrichta 90.26 0.00e+00 1090.00
IUUC-Tni-120041 Tetraodon nigroviridis 83.04 0.00e+00 1004.00
IUUC-Tbe-127655 Tupaia belangeri 91.78 0.00e+00 1064.00
IUUC-Ttr-129249 Tursiops truncatus 98.46 0.00e+00 1211.00
IUUC-Vpa-130034 Vicugna pacos 97.09 0.00e+00 1188.00
IUUC-Xtr-132964 Xenopus tropicalis 87.39 0.00e+00 1060.00
IUUC-Xma-133894 Xiphophorus maculatus 84.06 0.00e+00 1007.00
Created Date 25-Jun-2017

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