iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036430

Ensembl Protein ID

ENSFCAP00000002366.3

UniProt Accession

M3VYR4; M3VYR4_FELCA

Genbank Protein ID

ENSFCAP00000002366

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02042637

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000002568.3	ENSFCAT00000002568.3	ENSFCAP00000002366.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	78.92	0.00e+00	1770.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Felis catus

Protein Sequence
(Fasta)

PTAQNRVRGE VSPTMTSTGQ DSTSTRQRRS RHNPHSPPHD SSVTSKRGVK KGAILSSSPS 60
LAEVKKKGRM KKLSQAAEQD LIMDLRRLDL NLEAKTLSGT GLVFDEQLNE FHCLWDDSFP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCACCGCCC AGAACCGCGT CAGGGGTGAA GTCTCCCCGA CCATGACCTC CACGGGCCAG 60
GATTCCACCT CAACCAGGCA GCGAAGGAGT AGGCATAACC CCCATTCGCC CCCCCACGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	40.95	3.00e-72	266.00
IUUC-Aml-002087	Ailuropoda melanoleuca	87.49	0.00e+00	1989.00
IUUC-Atr-002745	Amborella trichopoda	43.47	1.00e-85	310.00
IUUC-Aca-004303	Anolis carolinensis	58.82	0.00e+00	1012.00
IUUC-Aly-006432	Arabidopsis lyrata	44.23	9.00e-82	298.00
IUUC-Ath-007355	Arabidopsis thaliana	44.23	1.00e-86	314.00
IUUC-Ago-007972	Ashbya gossypii	41.76	4.00e-82	299.00
IUUC-Acl-008187	Aspergillus clavatus	44.20	5.00e-86	312.00
IUUC-Afl-008399	Aspergillus flavus	48.15	4.00e-48	185.00
IUUC-Afu-008954	Aspergillus fumigatus	40.65	2.00e-74	273.00
IUUC-Ani-009142	Aspergillus nidulans	44.38	4.00e-78	286.00
IUUC-Ang-009522	Aspergillus niger	35.80	4.00e-51	196.00
IUUC-Aor-010069	Aspergillus oryzae	41.19	5.00e-76	278.00
IUUC-Ate-010291	Aspergillus terreus	42.40	1.00e-86	314.00
IUUC-Ame-010780	Astyanax mexicanus	51.13	0.00e+00	791.00
IUUC-Bta-013052	Bos taurus	79.70	0.00e+00	1768.00
IUUC-Bci-013789	Botrytis cinerea	39.60	1.00e-78	288.00
IUUC-Bdi-014007	Brachypodium distachyon	43.18	3.00e-85	309.00
IUUC-Bol-015468	Brassica oleracea	43.43	3.00e-84	306.00
IUUC-Bra-016680	Brassica rapa	44.69	9.00e-85	307.00
IUUC-Cel-018220	Caenorhabditis elegans	39.21	5.00e-150	525.00
IUUC-Cja-019473	Callithrix jacchus	76.86	0.00e+00	1455.00
IUUC-Cfa-020263	Canis familiaris	88.46	0.00e+00	1961.00
IUUC-Cpo-021691	Cavia porcellus	79.67	0.00e+00	1801.00
IUUC-Cre-022561	Chlamydomonas reinhardtii	53.74	5.00e-56	210.00
IUUC-Csa-024223	Chlorocebus sabaeus	81.86	0.00e+00	1551.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	40.05	3.00e-79	289.00
IUUC-Cne-026978	Cryptococcus neoformans	43.11	2.00e-89	323.00
IUUC-Dre-028820	Danio rerio	57.16	0.00e+00	940.00
IUUC-Dno-029160	Dasypus novemcinctus	75.56	0.00e+00	1654.00
IUUC-Dor-030859	Dipodomys ordii	69.22	0.00e+00	1634.00
IUUC-Dse-031186	Dothistroma septosporum	41.71	2.00e-82	300.00
IUUC-Dme-031963	Drosophila melanogaster	43.54	0.00e+00	704.00
IUUC-Ete-032279	Echinops telfairi	67.93	2.00e-157	550.00
IUUC-Eca-033842	Equus caballus	84.85	0.00e+00	1963.00
IUUC-Eeu-034487	Erinaceus europaeus	77.81	7.00e-160	558.00
IUUC-Fox-038067	Fusarium oxysporum	40.80	1.00e-82	300.00
IUUC-Fso-038263	Fusarium solani	41.79	2.00e-83	303.00
IUUC-Ggr-040062	Gaeumannomyces graminis	40.48	2.00e-75	276.00
IUUC-Gma-043738	Glycine max	45.43	1.00e-87	317.00
IUUC-Ggo-045022	Gorilla gorilla	81.01	0.00e+00	1543.00
IUUC-Hsa-046904	Homo sapiens	85.92	0.00e+00	1538.00
IUUC-Hvu-047285	Hordeum vulgare	46.44	5.00e-86	310.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	79.88	0.00e+00	1837.00
IUUC-Kpa-049281	Komagataella pastoris	40.92	1.00e-84	307.00
IUUC-Lch-050330	Latimeria chalumnae	45.79	0.00e+00	953.00
IUUC-Lpe-051214	Leersia perrieri	39.40	1.00e-87	317.00
IUUC-Lma-053263	Leptosphaeria maculans	43.70	1.00e-90	327.00
IUUC-Laf-053386	Loxodonta africana	79.08	0.00e+00	1764.00
IUUC-Mcc-055530	Macaca mulatta	86.35	0.00e+00	1540.00
IUUC-Meu-056442	Macropus eugenii	68.51	0.00e+00	979.00
IUUC-Mor-057095	Magnaporthe oryzae	40.35	4.00e-86	312.00
IUUC-Mpo-057389	Magnaporthe poae	42.17	3.00e-75	276.00
IUUC-Mtr-058463	Medicago truncatula	42.90	9.00e-88	317.00
IUUC-Mla-059143	Melampsora laricipopulina	44.87	6.00e-84	305.00
IUUC-Mmr-060637	Microcebus murinus	79.01	0.00e+00	1828.00
IUUC-Mdo-062198	Monodelphis domestica	68.10	0.00e+00	1086.00
IUUC-Mmu-063346	Mus musculus	75.17	0.00e+00	1708.00
IUUC-Mac-064630	Musa acuminata	38.35	7.00e-84	305.00
IUUC-Mpu-065884	Mustela putorius furo	85.98	0.00e+00	1969.00
IUUC-Mlu-068117	Myotis lucifugus	80.43	0.00e+00	1799.00
IUUC-Nfi-068404	Neosartorya fischeri	43.78	5.00e-86	312.00
IUUC-Ncr-068672	Neurospora crassa	41.27	2.00e-82	300.00
IUUC-Nle-069868	Nomascus leucogenys	90.91	0.00e+00	735.00
IUUC-Opr-071074	Ochotona princeps	65.69	0.00e+00	1023.00
IUUC-Ont-072246	Oreochromis niloticus	45.80	0.00e+00	931.00
IUUC-Oan-072911	Ornithorhynchus anatinus	62.88	8.00e-110	391.00
IUUC-Ocu-074627	Oryctolagus cuniculus	79.95	0.00e+00	1850.00
IUUC-Oba-075489	Oryza barthii	46.15	2.00e-85	310.00
IUUC-Obr-076150	Oryza brachyantha	37.71	4.00e-86	312.00
IUUC-Ogl-077437	Oryza glaberrima	43.38	3.00e-86	312.00
IUUC-Ogu-078370	Oryza glumaepatula	43.66	7.00e-87	315.00
IUUC-Oin-079210	Oryza indica	43.66	7.00e-87	315.00
IUUC-Olo-080971	Oryza longistaminata	47.31	1.00e-74	274.00
IUUC-Oni-082031	Oryza nivara	43.66	1.00e-86	314.00
IUUC-Opu-083471	Oryza punctata	45.43	2.00e-85	309.00
IUUC-Oru-084755	Oryza rufipogon	43.66	8.00e-87	314.00
IUUC-Osa-085447	Oryza sativa	43.66	7.00e-87	315.00
IUUC-Oga-089155	Otolemur garnettii	77.74	0.00e+00	1790.00
IUUC-Oar-089620	Ovis aries	79.26	0.00e+00	1772.00
IUUC-Ptr-090812	Pan troglodytes	88.73	0.00e+00	1256.00
IUUC-Pan-092340	Papio anubis	81.66	0.00e+00	1536.00
IUUC-Pma-094386	Petromyzon marinus	53.68	0.00e+00	822.00
IUUC-Pno-095131	Phaeosphaeria nodorum	46.82	6.00e-77	281.00
IUUC-Ppa-095550	Physcomitrella patens	46.56	8.00e-91	328.00
IUUC-Pfo-096110	Poecilia formosa	56.13	0.00e+00	728.00
IUUC-Pab-098422	Pongo abelii	80.46	0.00e+00	1503.00
IUUC-Pop-099174	Populus trichocarpa	42.18	2.00e-83	303.00
IUUC-Pca-100833	Procavia capensis	76.53	0.00e+00	1604.00
IUUC-Ppe-101644	Prunus persica	43.18	2.00e-87	316.00
IUUC-Pva-102410	Pteropus vampyrus	77.64	0.00e+00	1693.00
IUUC-Ptt-103841	Puccinia triticina	39.29	2.00e-80	293.00
IUUC-Pte-104383	Pyrenophora teres	43.12	6.00e-86	312.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	43.08	2.00e-86	313.00
IUUC-Rno-105131	Rattus norvegicus	74.29	0.00e+00	1697.00
IUUC-Sce-106274	Saccharomyces cerevisiae	40.00	2.00e-80	293.00
IUUC-Sha-106661	Sarcophilus harrisii	56.00	0.00e+00	833.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	41.56	1.00e-89	323.00
IUUC-Spo-108300	Schizosaccharomyces pombe	46.05	2.00e-89	323.00
IUUC-Smo-109615	Selaginella moellendorffii	45.20	1.00e-88	320.00
IUUC-Sit-110160	Setaria italica	43.13	7.00e-82	298.00
IUUC-Sly-111164	Solanum lycopersicum	40.17	1.00e-82	300.00
IUUC-Stu-112685	Solanum tuberosum	42.51	2.00e-72	266.00
IUUC-Sar-113692	Sorex araneus	67.28	0.00e+00	788.00
IUUC-Sbi-114301	Sorghum bicolor	46.79	1.00e-81	297.00
IUUC-Sre-115013	Sporisorium reilianum	42.93	1.00e-81	297.00
IUUC-Ssc-115724	Sus scrofa	82.44	0.00e+00	1749.00
IUUC-Tgu-116605	Taeniopygia guttata	47.81	0.00e+00	689.00
IUUC-Tru-117614	Takifugu rubripes	55.90	0.00e+00	868.00
IUUC-Tsy-118807	Tarsius syrichta	71.03	0.00e+00	833.00
IUUC-Tni-119809	Tetraodon nigroviridis	56.26	0.00e+00	808.00
IUUC-Tca-121312	Theobroma cacao	46.20	7.00e-86	311.00
IUUC-Tre-121930	Trichoderma reesei	40.05	5.00e-84	305.00
IUUC-Tvi-122373	Trichoderma virens	40.64	5.00e-85	308.00
IUUC-Tae-123064	Triticum aestivum	42.18	1.00e-78	286.00
IUUC-Tme-127027	Tuber melanosporum	42.23	2.00e-73	269.00
IUUC-Tbe-127675	Tupaia belangeri	51.44	3.00e-81	296.00
IUUC-Ttr-128411	Tursiops truncatus	81.19	0.00e+00	1845.00
IUUC-Uma-129408	Ustilago maydis	47.08	1.00e-75	277.00
IUUC-Vda-129994	Verticillium dahliae	38.90	4.00e-75	276.00
IUUC-Vpa-130525	Vicugna pacos	81.91	4.00e-62	233.00
IUUC-Vvi-131038	Vitis vinifera	42.30	2.00e-86	313.00
IUUC-Xtr-132618	Xenopus tropicalis	58.13	0.00e+00	977.00
IUUC-Xma-133730	Xiphophorus maculatus	49.51	0.00e+00	721.00
IUUC-Yli-134680	Yarrowia lipolytica	42.27	5.00e-85	308.00
IUUC-Zma-135110	Zea mays	45.24	2.00e-82	299.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence