iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054137

Ensembl Protein ID

ENSLAFP00000018701.1

UniProt Accession

G3TSZ3; G3TSZ3_LOXAF

Protein Name

Uncharacterized protein

Gene Name

EML2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000031949.1	ENSLAFT00000027318.1	ENSLAFP00000018701.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-15	56.8	289	317

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtcla.fsd.tllvsGsdDgtikvWD 29
           H ++v++l+ + d tl++ G++D  + +W 
   Q: 289  HDGGVFGLCaL-DgTLVSGGGRDRRVVLWG 317
           999****8647.636656688********6 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSSFGPGKTK EVIFSMAEEG SVKMFLRGRP VPMLIPDELA PTYSLDTRSE LPACRLKLDW 60
VSYGYRGRDC RANLYLLPTG EIVYFVASVA VLYSVEEQRQ RHYLGHNDDI KCMAVHPDMV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTAGCT TTGGACCTGG GTGAGACCCT CTCGCAGACA GCCTCTTACC CCTACTCCCG 60
GGTCCCGCGC TCCAGGTCTT CTCCCCAGGG ACCCAGGTCG GCGAGCGTTC ACCCTTTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005108--HELP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0072686--C:mitotic spindle
GO:0031115--P:negative regulation of microtubule polymerization
GO:0010968--P:regulation of microtubule nucleation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002155	Ailuropoda melanoleuca	90.60	0.00e+00	1179.00
IUUC-Aca-005316	Anolis carolinensis	76.24	0.00e+00	968.00
IUUC-Bta-013267	Bos taurus	90.60	0.00e+00	1188.00
IUUC-Cja-019146	Callithrix jacchus	86.04	0.00e+00	1145.00
IUUC-Cfa-020267	Canis familiaris	91.22	0.00e+00	1186.00
IUUC-Dno-028961	Dasypus novemcinctus	88.20	0.00e+00	1119.00
IUUC-Eca-033785	Equus caballus	90.12	0.00e+00	1167.00
IUUC-Eeu-035302	Erinaceus europaeus	94.02	0.00e+00	710.00
IUUC-Fca-036170	Felis catus	90.02	0.00e+00	1170.00
IUUC-Ggo-044669	Gorilla gorilla	89.04	0.00e+00	1164.00
IUUC-Hsa-046141	Homo sapiens	90.74	0.00e+00	1185.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	89.40	0.00e+00	1160.00
IUUC-Mcc-055780	Macaca mulatta	89.89	0.00e+00	1096.00
IUUC-Meu-056664	Macropus eugenii	79.72	0.00e+00	1054.00
IUUC-Mmr-060853	Microcebus murinus	89.66	0.00e+00	1169.00
IUUC-Mdo-062224	Monodelphis domestica	82.53	0.00e+00	949.00
IUUC-Mmu-063860	Mus musculus	89.64	0.00e+00	1169.00
IUUC-Mpu-066043	Mustela putorius furo	91.81	0.00e+00	1186.00
IUUC-Mlu-067125	Myotis lucifugus	67.58	0.00e+00	790.00
IUUC-Nle-069618	Nomascus leucogenys	81.30	0.00e+00	1007.00
IUUC-Ocu-074087	Oryctolagus cuniculus	81.89	0.00e+00	827.00
IUUC-Oga-088048	Otolemur garnettii	86.75	0.00e+00	1122.00
IUUC-Oar-089907	Ovis aries	90.33	0.00e+00	1151.00
IUUC-Pan-092082	Papio anubis	90.45	0.00e+00	1182.00
IUUC-Pab-097619	Pongo abelii	90.67	0.00e+00	1191.00
IUUC-Pca-101070	Procavia capensis	81.80	0.00e+00	1033.00
IUUC-Pva-102957	Pteropus vampyrus	89.85	0.00e+00	1177.00
IUUC-Rno-105074	Rattus norvegicus	88.82	0.00e+00	1150.00
IUUC-Sha-106692	Sarcophilus harrisii	84.14	0.00e+00	1104.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence