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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063093
Ensembl Protein ID ENSMUSP00000022226.4
UniProt Accession Q8CEC6; Q0VEA0; PPWD1_MOUSE
Genbank Protein ID BAC25996.1; AAI19283.1; AAI19311.1
Protein Name Peptidylprolyl isomerase domain and WD repeat-containing protein 1
Genbank Nucleotide ID AK028532; BC119282; BC119310
Gene Name Ppwd1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000021713.8 ENSMUST00000022226.4 ENSMUSP00000022226.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarmiRNAMap
RAID2
Protein-protein Interaction
IIDMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.80e-09 36.8 89 117
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWD 29
           H d +t +    +++++++s+Dg +k W 
   Q: 89   HRDVITHVVCtKTDFIITASHDGHVKFWK 117
           788888875543389*************7 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Putative peptidylprolyl isomerase (PPIase). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing (By similarity).
 Putative peptidylprolyl isomerase (PPIase). PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing (By similarity).
Protein Sequence
(Fasta)
MATESGSDSQ LRRRRRRDPE GSEKTELSER EPALAVAGSE ENDDENEERW VGPLPVEATL 60
AKKRKVLEFE RVYLDNLPSA SMYERSYMHR DVITHVVCTK TDFIITASHD GHVKFWKKIE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063093|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TAGTTCACTC GGTCGTCGCG TCTCTTCTAA CGCCTCGGAC GACATGGCGA CCGAGAGTGG 60
GAGCGATTCG CAGCTGAGGA GGAGAAGGCG CCGAGACCCA GAGGGATCAG AAAAAACGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063093|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0413--Isomerase
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0697--Rotamase
KW-0747--Spliceosome
KW-0853--WD repeat
Interpro

IPR029000--Cyclophilin-like_dom
IPR024936--Cyclophilin-type_PPIase
IPR002130--Cyclophilin-type_PPIase_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50072--CSA_PPIASE_2
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00160--Pro_isomerase
PF00400--WD40
PRINTS

PR00153--CSAPPISMRASE
SMART

SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0016604--C:nuclear body
GO:0003755--F:peptidyl-prolyl cis-trans isomerase activity
GO:0006397--P:mRNA processing
GO:0006457--P:protein folding
GO:0008380--P:RNA splicing
KEGG mmu:238831
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000971 Aegilops tauschii 52.19 5.00e-177 614.00
IUUC-Aml-001897 Ailuropoda melanoleuca 96.75 0.00e+00 1280.00
IUUC-Apl-003599 Anas platyrhynchos 93.52 0.00e+00 1159.00
IUUC-Aca-004814 Anolis carolinensis 93.63 0.00e+00 1199.00
IUUC-Aly-005546 Arabidopsis lyrata 54.31 0.00e+00 658.00
IUUC-Acl-008086 Aspergillus clavatus 48.67 1.00e-161 563.00
IUUC-Afu-008839 Aspergillus fumigatus 48.58 7.00e-160 557.00
IUUC-Ani-009162 Aspergillus nidulans 50.25 1.00e-160 560.00
IUUC-Ang-009524 Aspergillus niger 49.83 6.00e-168 584.00
IUUC-Ate-010284 Aspergillus terreus 48.93 4.00e-164 571.00
IUUC-Ame-011100 Astyanax mexicanus 84.86 0.00e+00 990.00
IUUC-Bgr-012307 Blumeria graminis 42.44 3.00e-87 315.00
IUUC-Bta-012821 Bos taurus 96.44 0.00e+00 1272.00
IUUC-Bci-013978 Botrytis cinerea 48.59 2.00e-165 575.00
IUUC-Bdi-014828 Brachypodium distachyon 52.33 0.00e+00 647.00
IUUC-Cja-018769 Callithrix jacchus 97.06 0.00e+00 1259.00
IUUC-Cfa-020555 Canis familiaris 96.13 0.00e+00 1247.00
IUUC-Cpo-022169 Cavia porcellus 95.82 0.00e+00 1256.00
IUUC-Cre-022808 Chlamydomonas reinhardtii 48.75 3.00e-138 485.00
IUUC-Csa-023086 Chlorocebus sabaeus 97.21 0.00e+00 1259.00
IUUC-Cin-025611 Ciona intestinalis 62.96 0.00e+00 781.00
IUUC-Csv-026237 Ciona savignyi 57.37 0.00e+00 726.00
IUUC-Cgl-026661 Colletotrichum gloeosporioides 49.25 3.00e-168 585.00
IUUC-Dre-028591 Danio rerio 85.79 0.00e+00 1113.00
IUUC-Dno-029074 Dasypus novemcinctus 94.14 0.00e+00 1224.00
IUUC-Dor-030544 Dipodomys ordii 88.09 0.00e+00 1100.00
IUUC-Dse-031430 Dothistroma septosporum 48.76 8.00e-163 566.00
IUUC-Dme-031943 Drosophila melanogaster 60.37 0.00e+00 760.00
IUUC-Eca-034176 Equus caballus 96.59 0.00e+00 1258.00
IUUC-Fca-036583 Felis catus 96.28 0.00e+00 1275.00
IUUC-Fal-037662 Ficedula albicollis 95.04 0.00e+00 1148.00
IUUC-Fox-037831 Fusarium oxysporum 46.37 3.00e-152 531.00
IUUC-Fso-038360 Fusarium solani 46.93 1.00e-151 530.00
IUUC-Gmo-039705 Gadus morhua 83.19 0.00e+00 1064.00
IUUC-Ggr-040077 Gaeumannomyces graminis 47.85 5.00e-160 558.00
IUUC-Gga-040138 Gallus gallus 93.81 0.00e+00 1199.00
IUUC-Gac-042647 Gasterosteus aculeatus 83.61 0.00e+00 1081.00
IUUC-Ggo-045218 Gorilla gorilla 97.52 0.00e+00 1288.00
IUUC-Hsa-045940 Homo sapiens 97.21 0.00e+00 1286.00
IUUC-Hvu-047090 Hordeum vulgare 52.36 0.00e+00 630.00
IUUC-Itr-048024 Ictidomys tridecemlineatus 97.37 0.00e+00 1288.00
IUUC-Lch-049614 Latimeria chalumnae 87.94 0.00e+00 1137.00
IUUC-Lpe-051688 Leersia perrieri 53.23 0.00e+00 653.00
IUUC-Loc-051834 Lepisosteus oculatus 86.96 0.00e+00 1118.00
IUUC-Lma-052989 Leptosphaeria maculans 48.12 3.00e-153 535.00
IUUC-Laf-054056 Loxodonta africana 96.44 0.00e+00 1273.00
IUUC-Mcc-055891 Macaca mulatta 97.52 0.00e+00 1264.00
IUUC-Meu-056503 Macropus eugenii 88.93 0.00e+00 1132.00
IUUC-Mor-057121 Magnaporthe oryzae 47.77 3.00e-160 558.00
IUUC-Mpo-057304 Magnaporthe poae 48.02 2.00e-162 565.00
IUUC-Mmr-061049 Microcebus murinus 96.28 0.00e+00 1259.00
IUUC-Mdo-062399 Monodelphis domestica 95.78 0.00e+00 1237.00
IUUC-Mpu-066077 Mustela putorius furo 96.75 0.00e+00 1283.00
IUUC-Mlu-066977 Myotis lucifugus 95.98 0.00e+00 1263.00
IUUC-Nfi-068247 Neosartorya fischeri 48.75 8.00e-161 560.00
IUUC-Ncr-068924 Neurospora crassa 48.12 1.00e-158 553.00
IUUC-Nle-069866 Nomascus leucogenys 97.21 0.00e+00 1258.00
IUUC-Opr-071094 Ochotona princeps 90.87 0.00e+00 1175.00
IUUC-Ont-071762 Oreochromis niloticus 85.79 0.00e+00 1108.00
IUUC-Oan-073117 Ornithorhynchus anatinus 81.29 0.00e+00 986.00
IUUC-Ocu-074295 Oryctolagus cuniculus 96.28 0.00e+00 1273.00
IUUC-Obr-076638 Oryza brachyantha 52.20 0.00e+00 642.00
IUUC-Ogl-077801 Oryza glaberrima 52.98 0.00e+00 642.00
IUUC-Oin-079614 Oryza indica 46.27 1.00e-105 377.00
IUUC-Opu-083158 Oryza punctata 51.87 0.00e+00 644.00
IUUC-Ola-087124 Oryzias latipes 85.45 0.00e+00 1104.00
IUUC-Olu-087758 Ostreococcus lucimarinus 50.08 6.00e-167 580.00
IUUC-Oga-088254 Otolemur garnettii 95.51 0.00e+00 1271.00
IUUC-Oar-089414 Ovis aries 96.75 0.00e+00 1275.00
IUUC-Ptr-091471 Pan troglodytes 97.37 0.00e+00 1286.00
IUUC-Pan-091762 Papio anubis 97.37 0.00e+00 1260.00
IUUC-Psi-093822 Pelodiscus sinensis 93.83 0.00e+00 1192.00
IUUC-Pma-094613 Petromyzon marinus 74.78 4.00e-157 547.00
IUUC-Ppa-095551 Physcomitrella patens 51.08 0.00e+00 630.00
IUUC-Pfo-096544 Poecilia formosa 86.29 0.00e+00 1110.00
IUUC-Pab-098657 Pongo abelii 96.90 0.00e+00 1280.00
IUUC-Pca-100456 Procavia capensis 95.67 0.00e+00 1265.00
IUUC-Pte-104062 Pyrenophora teres 47.28 1.00e-154 540.00
IUUC-Rno-106026 Rattus norvegicus 98.45 0.00e+00 1298.00
IUUC-Sha-106972 Sarcophilus harrisii 97.35 0.00e+00 1171.00
IUUC-Sja-107835 Schizosaccharomyces japonicus 41.17 5.00e-124 438.00
IUUC-Spo-108123 Schizosaccharomyces pombe 40.63 5.00e-120 425.00
IUUC-Smo-109088 Selaginella moellendorffii 53.76 0.00e+00 655.00
IUUC-Sit-110058 Setaria italica 51.91 0.00e+00 643.00
IUUC-Sbi-114363 Sorghum bicolor 51.58 0.00e+00 644.00
IUUC-Ssc-115357 Sus scrofa 96.44 0.00e+00 1276.00
IUUC-Tgu-116509 Taeniopygia guttata 93.98 0.00e+00 1202.00
IUUC-Tru-117813 Takifugu rubripes 83.78 0.00e+00 1078.00
IUUC-Tre-122148 Trichoderma reesei 48.42 4.00e-158 551.00
IUUC-Tvi-122519 Trichoderma virens 47.93 1.00e-157 550.00
IUUC-Tae-124690 Triticum aestivum 52.03 0.00e+00 639.00
IUUC-Tur-126759 Triticum urartu 52.20 0.00e+00 642.00
IUUC-Tme-127094 Tuber melanosporum 48.29 2.00e-151 529.00
IUUC-Tbe-128038 Tupaia belangeri 94.74 0.00e+00 1256.00
IUUC-Ttr-128520 Tursiops truncatus 85.76 0.00e+00 1107.00
IUUC-Vda-129717 Verticillium dahliae 47.76 6.00e-160 557.00
IUUC-Vpa-130129 Vicugna pacos 96.28 0.00e+00 1268.00
IUUC-Xtr-131757 Xenopus tropicalis 88.11 0.00e+00 1134.00
IUUC-Xma-133563 Xiphophorus maculatus 86.22 0.00e+00 1103.00
IUUC-Zma-135633 Zea mays 49.20 2.00e-180 626.00
Created Date 25-Jun-2017

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