iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011426

Ensembl Protein ID

ENSAMXP00000000685.1

UniProt Accession

W5JZC5; W5JZC5_ASTMX

Genbank Protein ID

ENSAMXP00000000685

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

APWO01050972

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000000678.1	ENSAMXT00000000685.1	ENSAMXP00000000685.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.20e-08	34.4	213	259

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C++ + +e  ++ C++  C  ewfH+ C++l+    +p+   w+CpkCr
   Q: 213  TYC-LCEQVSYGE--MIGCDNeqCPiEWFHFSCVGLT---YKPKGR-WYCPKCR 259
           69*.*******99..*****999*99***********...777775.******8 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MLGHYGGAER SQLLSYVEDY LECVESLPLD IQRNVSLLRE IDTKYQEILK EVDEVYEKYK 60
KESDGAQRKR LQMQLQRALI SSQELGDEKI HVVTQMMELV ENRSRQMEAH SPCFLEPGET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATGTTTTCA TATATTTTGC AAGACCTGCA AGACTACATT TGGGCAAAAA TATTTCTAAT 60
ATACCGGTTA TCACTTTTGT TCCCCTTCTT TATATAATAA AAATATATGA TTATATATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0042981--P:regulation of apoptotic process
GO:2000772--P:regulation of cellular senescence

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	71.53	1.00e-83	302.00
IUUC-Aca-004990	Anolis carolinensis	71.27	1.00e-85	309.00
IUUC-Bta-012721	Bos taurus	71.90	3.00e-84	304.00
IUUC-Cja-018960	Callithrix jacchus	74.09	2.00e-76	279.00
IUUC-Cfa-020869	Canis familiaris	71.53	3.00e-83	301.00
IUUC-Cpo-021414	Cavia porcellus	70.80	3.00e-83	301.00
IUUC-Csa-023304	Chlorocebus sabaeus	72.26	3.00e-77	281.00
IUUC-Dre-028562	Danio rerio	85.71	3.00e-119	421.00
IUUC-Dno-029945	Dasypus novemcinctus	70.80	3.00e-83	301.00
IUUC-Dor-030141	Dipodomys ordii	70.07	3.00e-82	297.00
IUUC-Ete-032709	Echinops telfairi	72.73	4.00e-92	330.00
IUUC-Eca-033432	Equus caballus	71.90	9.00e-84	303.00
IUUC-Eeu-035285	Erinaceus europaeus	71.96	5.00e-68	250.00
IUUC-Fca-036467	Felis catus	71.90	7.00e-84	303.00
IUUC-Gmo-038748	Gadus morhua	69.12	7.00e-97	346.00
IUUC-Gac-041403	Gasterosteus aculeatus	68.90	1.00e-99	355.00
IUUC-Hsa-045837	Homo sapiens	72.26	3.00e-77	281.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	71.17	6.00e-83	300.00
IUUC-Lch-049965	Latimeria chalumnae	70.36	1.00e-93	335.00
IUUC-Mcc-055155	Macaca mulatta	70.81	4.00e-54	203.00
IUUC-Meu-056470	Macropus eugenii	73.21	1.00e-91	328.00
IUUC-Mga-059570	Meleagris gallopavo	68.80	4.00e-74	270.00
IUUC-Mmr-061385	Microcebus murinus	71.90	8.00e-77	280.00
IUUC-Mdo-062144	Monodelphis domestica	73.21	2.00e-91	328.00
IUUC-Mmu-063215	Mus musculus	73.72	2.00e-83	302.00
IUUC-Mpu-065749	Mustela putorius furo	70.80	7.00e-74	270.00
IUUC-Ont-071524	Oreochromis niloticus	69.15	1.00e-101	362.00
IUUC-Ocu-074870	Oryctolagus cuniculus	71.90	3.00e-84	304.00
IUUC-Ola-087400	Oryzias latipes	68.64	2.00e-72	264.00
IUUC-Oga-088336	Otolemur garnettii	72.26	4.00e-77	280.00
IUUC-Oar-090136	Ovis aries	71.53	5.00e-84	303.00
IUUC-Pan-092819	Papio anubis	72.26	3.00e-77	281.00
IUUC-Pfo-096633	Poecilia formosa	71.83	8.00e-92	330.00
IUUC-Pab-098346	Pongo abelii	72.26	3.00e-77	281.00
IUUC-Pca-100278	Procavia capensis	70.57	1.00e-89	322.00
IUUC-Pva-103190	Pteropus vampyrus	71.90	3.00e-84	304.00
IUUC-Rno-104940	Rattus norvegicus	72.99	5.00e-82	297.00
IUUC-Sha-107533	Sarcophilus harrisii	73.21	2.00e-92	332.00
IUUC-Sar-113630	Sorex araneus	71.03	4.00e-67	247.00
IUUC-Ssc-115734	Sus scrofa	71.90	4.00e-84	304.00
IUUC-Tru-118168	Takifugu rubripes	65.72	3.00e-91	328.00
IUUC-Tsy-119494	Tarsius syrichta	71.14	8.00e-62	229.00
IUUC-Tni-119663	Tetraodon nigroviridis	68.20	3.00e-94	337.00
IUUC-Ttr-128442	Tursiops truncatus	71.03	3.00e-67	247.00
IUUC-Vpa-130063	Vicugna pacos	72.63	7.00e-85	306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence