iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054382

UUCD1 version

UUC-LoA-01048

Ensembl Protein ID

ENSLAFP00000000594.3

UniProt Accession

G3SM78; G3SM78_LOXAF

Protein Name

Uncharacterized protein

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000000705.3	ENSLAFT00000000705.3	ENSLAFP00000000594.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.50e-48	165.1	41	230

Active Site

Position(s)	Description	Evidence
48	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
51	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
224		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
            i+ktkgDGnC++rA+++s                                                          ll+vf+d+s+sd
   Q: 41   SIRKTKGDGNCFYRALGYSylesllgrsreilrfkervlqtpndllaagfeehkfrnffnafysvvelvekdgsvssLLKVFNDQSTSD 129
           699************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
           ++v++Lr+lts+++++++dff++fi+e++d+k+fc ++vep+a  +++i+i+aL+q+L+++++v++vd++++    +l++++fpe++  
   Q: 130  HIVQFLRLLTSAFIKNRADFFRHFIDEEMDIKDFCAHEVEPMAMeCDHIQITALSQALNIALQVEYVDEMDT----ALNHHVFPEAA-S 213
           **********************************************************************95....***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlY+++HY++L+a
   Q: 214  PSVYLLYKTSHYNILYA 230
           ***************97 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

QSETSFNLIS EKCDILSILR DHPENRIYQR KIQELSKRFT SIRKTKGDGN CFYRALGYSY 60
LESLLGRSRE ILRFKERVLQ TPNDLLAAGF EEHKFRNFFN AFYSVVELVE KDGSVSSLLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAGTGAAA CATCTTTCAA CCTAATATCA GAAAAATGTG ACATTCTGTC CATTCTTCGG 60
GATCACCCTG AAAACAGGAT TTACCAGCGG AAAATCCAGG TGAGGCAGAA GGGAGGGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	95.73	4.00e-134	469.00
IUUC-Bta-012766	Bos taurus	96.12	3.00e-132	463.00
IUUC-Cja-019480	Callithrix jacchus	94.81	1.00e-130	458.00
IUUC-Cfa-021106	Canis familiaris	96.58	5.00e-135	473.00
IUUC-Cpo-022187	Cavia porcellus	94.42	7.00e-131	459.00
IUUC-Csa-023493	Chlorocebus sabaeus	94.85	1.00e-131	462.00
IUUC-Cho-024411	Choloepus hoffmanni	78.05	9.00e-87	312.00
IUUC-Dno-029346	Dasypus novemcinctus	97.85	3.00e-135	473.00
IUUC-Dor-031012	Dipodomys ordii	96.12	8.00e-133	465.00
IUUC-Ete-032266	Echinops telfairi	89.27	1.00e-122	432.00
IUUC-Eca-033356	Equus caballus	96.15	2.00e-133	467.00
IUUC-Eeu-034775	Erinaceus europaeus	94.85	7.00e-132	462.00
IUUC-Fca-035363	Felis catus	96.14	5.00e-133	466.00
IUUC-Ggo-045023	Gorilla gorilla	94.40	1.00e-130	458.00
IUUC-Hsa-046984	Homo sapiens	94.83	3.00e-131	460.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	96.12	4.00e-133	466.00
IUUC-Lch-050514	Latimeria chalumnae	62.22	8.00e-85	306.00
IUUC-Loc-052003	Lepisosteus oculatus	51.80	1.00e-65	242.00
IUUC-Mcc-055516	Macaca mulatta	94.42	2.00e-131	460.00
IUUC-Meu-056038	Macropus eugenii	89.42	3.00e-100	357.00
IUUC-Mmr-060918	Microcebus murinus	97.41	3.00e-134	470.00
IUUC-Mdo-062638	Monodelphis domestica	91.38	1.00e-125	442.00
IUUC-Mmu-063973	Mus musculus	95.71	2.00e-132	465.00
IUUC-Mpu-066013	Mustela putorius furo	96.14	5.00e-134	469.00
IUUC-Mlu-067509	Myotis lucifugus	92.74	1.00e-128	451.00
IUUC-Nle-069673	Nomascus leucogenys	94.83	3.00e-131	460.00
IUUC-Opr-070761	Ochotona princeps	87.27	1.00e-80	291.00
IUUC-Oan-072922	Ornithorhynchus anatinus	84.72	9.00e-115	405.00
IUUC-Ocu-074643	Oryctolagus cuniculus	95.69	3.00e-132	463.00
IUUC-Oni-082026	Oryza nivara	30.09	2.00e-17	83.60
IUUC-Oru-084761	Oryza rufipogon	30.09	2.00e-17	83.60
IUUC-Ola-086603	Oryzias latipes	45.83	1.00e-52	199.00
IUUC-Oga-088936	Otolemur garnettii	94.85	5.00e-132	462.00
IUUC-Oar-089460	Ovis aries	96.57	5.00e-133	466.00
IUUC-Ptr-090805	Pan troglodytes	94.40	7.00e-131	459.00
IUUC-Pan-091969	Papio anubis	94.83	3.00e-131	460.00
IUUC-Pab-098476	Pongo abelii	94.42	3.00e-131	460.00
IUUC-Pca-100252	Procavia capensis	91.00	6.00e-53	200.00
IUUC-Pva-102204	Pteropus vampyrus	93.97	5.00e-131	459.00
IUUC-Pgr-103552	Puccinia graminis	75.00	2.60e-02	31.20
IUUC-Rno-105062	Rattus norvegicus	95.26	6.00e-132	462.00
IUUC-Sha-106968	Sarcophilus harrisii	91.30	9.00e-125	439.00
IUUC-Sar-113295	Sorex araneus	96.57	5.00e-132	462.00
IUUC-Ssc-115288	Sus scrofa	95.28	4.00e-132	463.00
IUUC-Tni-120440	Tetraodon nigroviridis	39.39	4.00e-43	167.00
IUUC-Tbe-127717	Tupaia belangeri	93.92	5.00e-78	282.00
IUUC-Ttr-128221	Tursiops truncatus	76.82	3.00e-100	357.00
IUUC-Uma-129443	Ustilago maydis	33.64	4.00e-25	108.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence