iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072928

UUCD1 version

UUC-OrA-00678

Ensembl Protein ID

ENSOANP00000019790.1

UniProt Accession

F7FM21; F7FM21_ORNAN

Protein Name

Uncharacterized protein

Gene Name

FBXO4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000012512.2	ENSOANT00000019793.2	ENSOANP00000019790.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	73.46	7.00e-113	404.00	IUUC-Hsa-046558
E3 adaptor/Cullin RING/SCF/F-box	30.00	1.70e-02	34.30	IUUC-Spo-108213

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

QRVARSYSNS ESPVCAWSYQ HLHIDVQLYI LSFLSPHDLC QLGSVDRYWN LTIRDPLLWR 60
YFLLRDLPSW SSVDWKSLPD MQILKNPFPK DTDGVLSDYM SIYKMSCPHT RRCLKSSHPI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAGGGTGG CTCGAAGTTA TAGCAATTCT GAATCACCCG TCTGTGCCTG GAGCTACCAA 60
CATTTGCACG TTAGCGTTCT CCTGGGAGTG AGAGGGATTT GGCCCAGATT CCCTCTCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom

Pfam

PF12937--F-box-like

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0007568--P:aging
GO:0019725--P:cellular homeostasis
GO:0071479--P:cellular response to ionizing radiation
GO:0035726--P:common myeloid progenitor cell proliferation
GO:0048147--P:negative regulation of fibroblast proliferation
GO:1900181--P:negative regulation of protein localization to nucleus
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:2000001--P:regulation of DNA damage checkpoint
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001232	Ailuropoda melanoleuca	73.08	4.00e-107	380.00
IUUC-Apl-004129	Anas platyrhynchos	63.55	5.00e-73	266.00
IUUC-Aca-005076	Anolis carolinensis	51.04	2.00e-70	259.00
IUUC-Ath-007114	Arabidopsis thaliana	32.50	1.30e-02	33.10
IUUC-Ame-011122	Astyanax mexicanus	48.75	1.00e-62	233.00
IUUC-Bta-012449	Bos taurus	78.24	3.00e-107	381.00
IUUC-Bol-015278	Brassica oleracea	31.03	1.00e-03	36.60
IUUC-Cja-019890	Callithrix jacchus	72.31	1.00e-107	382.00
IUUC-Cfa-021134	Canis familiaris	78.24	5.00e-106	377.00
IUUC-Cpo-021693	Cavia porcellus	77.22	2.00e-103	368.00
IUUC-Csa-023540	Chlorocebus sabaeus	73.08	2.00e-108	385.00
IUUC-Dre-028667	Danio rerio	46.91	8.00e-60	223.00
IUUC-Dno-028997	Dasypus novemcinctus	72.31	4.00e-107	380.00
IUUC-Dor-030135	Dipodomys ordii	67.36	3.00e-84	304.00
IUUC-Ete-033149	Echinops telfairi	68.46	1.00e-101	362.00
IUUC-Eca-033292	Equus caballus	77.22	6.00e-105	373.00
IUUC-Eeu-034504	Erinaceus europaeus	75.85	3.00e-103	367.00
IUUC-Fca-036476	Felis catus	74.23	3.00e-114	404.00
IUUC-Fal-036711	Ficedula albicollis	66.67	2.00e-87	315.00
IUUC-Gmo-039592	Gadus morhua	49.15	1.00e-59	223.00
IUUC-Gga-040924	Gallus gallus	64.00	4.00e-93	334.00
IUUC-Gac-041791	Gasterosteus aculeatus	52.72	1.00e-63	236.00
IUUC-Ggo-044736	Gorilla gorilla	73.46	1.00e-108	385.00
IUUC-Hsa-046558	Homo sapiens	73.46	9.00e-109	385.00
IUUC-Itr-048956	Ictidomys tridecemlineatus	73.85	3.00e-108	384.00
IUUC-Lch-049817	Latimeria chalumnae	66.80	7.00e-94	336.00
IUUC-Loc-052226	Lepisosteus oculatus	53.78	3.00e-69	254.00
IUUC-Laf-054371	Loxodonta africana	79.50	1.00e-108	385.00
IUUC-Mcc-054904	Macaca mulatta	73.08	2.00e-108	385.00
IUUC-Meu-056192	Macropus eugenii	65.25	5.00e-85	306.00
IUUC-Mmr-061692	Microcebus murinus	71.54	3.00e-106	377.00
IUUC-Mdo-062666	Monodelphis domestica	75.63	2.00e-101	362.00
IUUC-Mmu-064223	Mus musculus	71.54	1.00e-111	395.00
IUUC-Mpu-066290	Mustela putorius furo	74.23	4.00e-109	387.00
IUUC-Mlu-067882	Myotis lucifugus	76.99	9.00e-105	372.00
IUUC-Nle-070162	Nomascus leucogenys	73.46	6.00e-109	386.00
IUUC-Opr-070789	Ochotona princeps	69.41	7.00e-33	134.00
IUUC-Ont-071690	Oreochromis niloticus	51.00	8.00e-58	216.00
IUUC-Ocu-073857	Oryctolagus cuniculus	75.72	9.00e-106	375.00
IUUC-Ola-086607	Oryzias latipes	47.64	3.00e-59	221.00
IUUC-Oga-088929	Otolemur garnettii	78.24	8.00e-108	382.00
IUUC-Oar-089305	Ovis aries	77.82	2.00e-107	381.00
IUUC-Ptr-090813	Pan troglodytes	73.46	3.00e-109	387.00
IUUC-Pan-092924	Papio anubis	72.80	3.00e-107	380.00
IUUC-Psi-093237	Pelodiscus sinensis	68.55	3.00e-96	344.00
IUUC-Pfo-096259	Poecilia formosa	49.39	3.00e-65	241.00
IUUC-Pab-098292	Pongo abelii	73.46	6.00e-109	386.00
IUUC-Pva-102221	Pteropus vampyrus	74.62	1.00e-109	389.00
IUUC-Rno-105910	Rattus norvegicus	72.31	1.00e-112	399.00
IUUC-Sha-106998	Sarcophilus harrisii	75.31	7.00e-101	359.00
IUUC-Spo-108213	Schizosaccharomyces pombe	30.00	9.00e-03	34.30
IUUC-Sar-113033	Sorex araneus	76.26	7.00e-98	350.00
IUUC-Ssc-115507	Sus scrofa	77.41	7.00e-105	373.00
IUUC-Tgu-116502	Taeniopygia guttata	64.58	2.00e-81	295.00
IUUC-Tru-118203	Takifugu rubripes	49.23	9.00e-55	206.00
IUUC-Tni-120249	Tetraodon nigroviridis	48.46	2.00e-54	206.00
IUUC-Tur-126361	Triticum urartu	26.32	1.00e-02	33.50
IUUC-Tbe-128100	Tupaia belangeri	59.75	9.00e-74	269.00
IUUC-Ttr-128299	Tursiops truncatus	77.64	1.00e-105	375.00
IUUC-Vpa-130394	Vicugna pacos	78.15	2.00e-106	378.00
IUUC-Xtr-131825	Xenopus tropicalis	63.18	6.00e-88	317.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence