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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105425
Ensembl Protein ID ENSRNOP00000066789.1
UniProt Accession O35964; SH3G1_RAT
Genbank Protein ID AAC14882.1; BAA22921.1; AAH70893.1
Protein Name Endophilin-A2; Endophilin-2; SH3 domain protein 2B; SH3 domain-containing GRB2-like protein 1; SH3p8
Genbank Nucleotide ID AF009602; AB008161; BC070893
Gene Name Sh3gl1; Sh3p8
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000049683.2 ENSRNOT00000074695.2 ENSRNOP00000066789.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFACRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
Mentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusUniProt
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 1.30e-13 51.0 310 363
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +++lyd+e++nd+eL +++Gd +++   ++ de+W +g   l+g++G+fP  +v+ l
   Q: 310  SCKALYDFEPENDGELGFREGDLITLT--NQIDENWYEG--MLHGQSGFFPLSYVQVL 363
           69************************7..99********..8************9865 PP
   
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
 Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Protein Sequence
(Fasta)
MSVAGLKKQF YKASQLVSEK VGGAEGTKLD DDFREMEKKV DITSKAVAEV LVRTIEYLQP 60
NPASRAKLTM LNTVSKIRGQ VKNPGYPQSE GLLGECMVRH GKELGGESNF GDALLDAGES 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105425|UBD,SH3|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGGGGGCGC AGAGCTGGCA AGTTGATTTG GCGGTGGCGG CGCCTACCCC CGCGCGGAGG 60
AACGAAATCG GTTCGGCGAC GCCGGCGGAA ACCTTAGTTC GAGCGGGAAG CCTGACAGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105425|UBD,SH3|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0965--Cell junction
KW-0966--Cell projection
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0254--Endocytosis
KW-0967--Endosome
KW-0446--Lipid-binding
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR001452--SH3_domain
PROSITE

PS51021--BAR
PS50002--SH3
Pfam

PF03114--BAR
PF00018--SH3_1
PRINTS

PR00452--SH3DOMAIN
SMART

SM00721--BAR
SM00326--SH3
Gene Ontology

GO:0030054--C:cell junction
GO:0042995--C:cell projection
GO:0031901--C:early endosome membrane
GO:0002102--C:podosome
GO:0045202--C:synapse
GO:0051020--F:GTPase binding
GO:0008289--F:lipid binding
GO:0019902--F:phosphatase binding
GO:0016191--P:synaptic vesicle uncoating
KEGG rno:81922
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001620 Ailuropoda melanoleuca 91.67 0.00e+00 652.00
IUUC-Apl-004209 Anas platyrhynchos 86.80 5.00e-172 596.00
IUUC-Ame-011047 Astyanax mexicanus 74.80 5.00e-156 543.00
IUUC-Bta-012875 Bos taurus 92.93 0.00e+00 709.00
IUUC-Cel-018509 Caenorhabditis elegans 45.45 4.00e-94 338.00
IUUC-Cin-025799 Ciona intestinalis 51.22 1.00e-103 369.00
IUUC-Csv-026266 Ciona savignyi 52.49 5.00e-102 363.00
IUUC-Cne-027089 Cryptococcus neoformans 26.58 3.00e-08 53.50
IUUC-Dre-027986 Danio rerio 74.05 1.00e-154 539.00
IUUC-Dno-029193 Dasypus novemcinctus 93.48 0.00e+00 686.00
IUUC-Dor-030288 Dipodomys ordii 84.78 5.00e-173 600.00
IUUC-Eca-033277 Equus caballus 93.50 0.00e+00 651.00
IUUC-Fal-036965 Ficedula albicollis 87.03 0.00e+00 627.00
IUUC-Gmo-039523 Gadus morhua 72.21 5.00e-151 526.00
IUUC-Gga-040426 Gallus gallus 88.04 0.00e+00 630.00
IUUC-Gac-042642 Gasterosteus aculeatus 74.73 5.00e-157 546.00
IUUC-Ggo-045448 Gorilla gorilla 92.93 0.00e+00 683.00
IUUC-Hsa-046112 Homo sapiens 92.93 0.00e+00 682.00
IUUC-Itr-048752 Ictidomys tridecemlineatus 94.57 0.00e+00 696.00
IUUC-Lch-050334 Latimeria chalumnae 68.06 3.00e-133 468.00
IUUC-Loc-052447 Lepisosteus oculatus 77.21 3.00e-168 584.00
IUUC-Laf-053698 Loxodonta africana 93.48 0.00e+00 716.00
IUUC-Mcc-055547 Macaca mulatta 88.32 3.00e-177 614.00
IUUC-Meu-056398 Macropus eugenii 77.17 3.00e-166 577.00
IUUC-Mga-060168 Meleagris gallopavo 85.11 9.00e-171 592.00
IUUC-Mmr-061056 Microcebus murinus 92.66 0.00e+00 682.00
IUUC-Mmu-063596 Mus musculus 97.55 0.00e+00 703.00
IUUC-Mpu-066681 Mustela putorius furo 92.93 0.00e+00 684.00
IUUC-Mlu-068113 Myotis lucifugus 87.08 0.00e+00 631.00
IUUC-Nle-070104 Nomascus leucogenys 91.29 1.00e-174 605.00
IUUC-Opr-070661 Ochotona princeps 92.97 0.00e+00 681.00
IUUC-Ont-071922 Oreochromis niloticus 75.27 2.00e-157 548.00
IUUC-Ola-086645 Oryzias latipes 77.57 2.00e-172 597.00
IUUC-Oga-088627 Otolemur garnettii 91.81 0.00e+00 677.00
IUUC-Pan-092433 Papio anubis 92.18 0.00e+00 640.00
IUUC-Psi-092940 Pelodiscus sinensis 86.35 0.00e+00 645.00
IUUC-Pma-094657 Petromyzon marinus 63.54 1.00e-122 432.00
IUUC-Pfo-096876 Poecilia formosa 75.27 9.00e-158 549.00
IUUC-Pab-097667 Pongo abelii 79.89 2.00e-153 534.00
IUUC-Pca-100102 Procavia capensis 85.60 0.00e+00 645.00
IUUC-Pva-102731 Pteropus vampyrus 84.24 3.00e-173 600.00
IUUC-Pgr-103312 Puccinia graminis 24.37 8.00e-15 75.50
IUUC-Sha-106675 Sarcophilus harrisii 88.98 0.00e+00 667.00
IUUC-Ssc-115548 Sus scrofa 92.41 0.00e+00 663.00
IUUC-Tru-117979 Takifugu rubripes 76.09 4.00e-159 553.00
IUUC-Tni-120585 Tetraodon nigroviridis 76.36 3.00e-159 554.00
IUUC-Ttr-128449 Tursiops truncatus 92.09 0.00e+00 633.00
IUUC-Xtr-131935 Xenopus tropicalis 79.62 4.00e-165 573.00
Created Date 25-Jun-2017

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