iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028278

UUCD1 version

UUC-DaR-00695

Ensembl Protein ID

ENSDARP00000012238.5

UniProt Accession

F1QEG2; Q7SYD2; KL41B_DANRE

Genbank Protein ID

AAH54912.1

Protein Name

Kelch-like protein 41b; Kelch repeat and BTB domain-containing protein 10b

Genbank Nucleotide ID

CABZ01067487

Gene Name

klhl41b; kbtbd10b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000006757.5	ENSDART00000013588.5	ENSDARP00000012238.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.50e-18	65.3	33	99
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.40e-06	26.4	135	164

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmele.esksklmveikdvqpevfrallkFlYtgklde 67
           D++l++g++ f++h++++aa+S++F+ lf +e   e++ +++v+++dv+p  +  +l++lY+ ++d+
   Q: 33   DCTLKIGDRCFPCHRLIMAACSPYFRELFFSEDGkEKDIGKEVVLDDVDPNIMDMILQYLYSAEIDL 99
           9****************************6555559999*************************997 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 3    NclgilrfAdlydcpdLkdaaldfilkhFk 32
           Ncl+++r++  ++ p+L+ aa+dfi + F+
   Q: 135  NCLAVFRLGLVLSVPRLAIAARDFIADRFE 164
           ***************************995 PP

Organism

Danio rerio

Functional Description
(View)

Involved in skeletal muscle development and maintenance.

Protein Sequence
(Fasta)

MDPKAIKEEL RLFQSTLLQD GLKELLNENK FVDCTLKIGD RCFPCHRLIM AACSPYFREL 60
FFSEDGKEKD IGKEVVLDDV DPNIMDMILQ YLYSAEIDLV DDNVQEIFAV ANRFQIPSVF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTTTTCCAG CCCGGACGGT GTGGCGAGCA GACCTGCAGC CACCTTCTCC ACTTCTTTCT 60
CCTCTTTTAG TCGATTCTCA CTTTGAGACG AAACATCATG GATCCCAAAG CCATCAAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0256--Endoplasmic reticulum
KW-0880--Kelch repeat
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0703--Sarcoplasmic reticulum

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0031430--C:M band
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

KEGG

dre:321064

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002167	Ailuropoda melanoleuca	60.40	0.00e+00	774.00
IUUC-Apl-003866	Anas platyrhynchos	60.76	0.00e+00	775.00
IUUC-Ame-010909	Astyanax mexicanus	83.42	0.00e+00	1028.00
IUUC-Bta-012925	Bos taurus	60.26	0.00e+00	776.00
IUUC-Cja-019348	Callithrix jacchus	60.60	0.00e+00	779.00
IUUC-Cfa-020782	Canis familiaris	60.56	0.00e+00	778.00
IUUC-Cpo-021825	Cavia porcellus	59.11	0.00e+00	761.00
IUUC-Csa-023184	Chlorocebus sabaeus	60.50	0.00e+00	657.00
IUUC-Dno-029516	Dasypus novemcinctus	60.76	0.00e+00	778.00
IUUC-Dor-030850	Dipodomys ordii	56.85	2.00e-137	482.00
IUUC-Eca-033714	Equus caballus	60.26	0.00e+00	775.00
IUUC-Eeu-035245	Erinaceus europaeus	60.85	0.00e+00	716.00
IUUC-Gga-041106	Gallus gallus	61.26	0.00e+00	794.00
IUUC-Gac-042252	Gasterosteus aculeatus	73.93	0.00e+00	932.00
IUUC-Ggo-044817	Gorilla gorilla	60.43	0.00e+00	776.00
IUUC-Hsa-046620	Homo sapiens	60.43	0.00e+00	776.00
IUUC-Lch-050477	Latimeria chalumnae	61.98	0.00e+00	771.00
IUUC-Loc-051955	Lepisosteus oculatus	72.64	0.00e+00	917.00
IUUC-Laf-053500	Loxodonta africana	60.26	0.00e+00	772.00
IUUC-Mcc-055316	Macaca mulatta	60.60	0.00e+00	778.00
IUUC-Mmr-061444	Microcebus murinus	60.10	0.00e+00	775.00
IUUC-Mmu-064147	Mus musculus	60.60	0.00e+00	778.00
IUUC-Mlu-067481	Myotis lucifugus	59.27	0.00e+00	759.00
IUUC-Nle-069339	Nomascus leucogenys	60.60	0.00e+00	778.00
IUUC-Opr-070703	Ochotona princeps	60.60	0.00e+00	741.00
IUUC-Ont-072420	Oreochromis niloticus	76.61	0.00e+00	982.00
IUUC-Oan-073476	Ornithorhynchus anatinus	59.93	0.00e+00	772.00
IUUC-Ocu-074248	Oryctolagus cuniculus	60.76	0.00e+00	780.00
IUUC-Ola-086361	Oryzias latipes	75.13	0.00e+00	947.00
IUUC-Oar-090349	Ovis aries	60.43	0.00e+00	775.00
IUUC-Pan-092069	Papio anubis	60.60	0.00e+00	778.00
IUUC-Psi-093671	Pelodiscus sinensis	61.75	0.00e+00	780.00
IUUC-Pfo-096122	Poecilia formosa	74.59	0.00e+00	971.00
IUUC-Pab-098711	Pongo abelii	60.26	0.00e+00	775.00
IUUC-Pva-102401	Pteropus vampyrus	59.93	0.00e+00	773.00
IUUC-Rno-105969	Rattus norvegicus	60.43	0.00e+00	778.00
IUUC-Sar-113405	Sorex araneus	59.44	0.00e+00	757.00
IUUC-Tgu-116725	Taeniopygia guttata	62.09	0.00e+00	806.00
IUUC-Tsy-119225	Tarsius syrichta	56.95	0.00e+00	703.00
IUUC-Tni-120547	Tetraodon nigroviridis	73.88	0.00e+00	940.00
IUUC-Tur-126097	Triticum urartu	29.65	6.00e-12	65.10
IUUC-Ttr-128645	Tursiops truncatus	60.76	0.00e+00	779.00
IUUC-Vpa-130714	Vicugna pacos	60.60	0.00e+00	778.00
IUUC-Xtr-132144	Xenopus tropicalis	59.87	0.00e+00	787.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence