iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022516

Ensembl Protein ID

ENSCPOP00000003829.2

UniProt Accession

H0V2Q4; H0V2Q4_CAVPO

Genbank Protein ID

ENSCPOP00000003829

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02038413

Gene Name

MAP3K5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000004244.3	ENSCPOT00000004289.2	ENSCPOP00000003829.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	94.95	0.00e+00	2339.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

PPPPPAGAFW NVDSAAPGPG CPAAAPGSNA ARCRGNSSSG GGRRTTVAYV INEASQGQLV 60
VAESEALQSL REACEAVGAT LETLHFGKLD FGETAVLDRF YNADIAVVEM SDAFRQPSLF 120

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Nucleotide Sequence
(Fasta)

CCACCGCCGC CGCCAGCGGG GCAGCTTTCT GGAACGTGGA CAGCGCTGCA GCCCCGGCCC 60
TGGGTGTCCT GCCGCCGCCC CTGGGAGCAA CGCCGCCCGG TGCCGGGGCA ACTCCTCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:0097300--P:programmed necrotic cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	94.31	0.00e+00	2294.00
IUUC-Apl-003713	Anas platyrhynchos	87.67	0.00e+00	2043.00
IUUC-Aca-005331	Anolis carolinensis	86.74	0.00e+00	2051.00
IUUC-Ame-011158	Astyanax mexicanus	73.74	0.00e+00	1850.00
IUUC-Bta-012770	Bos taurus	93.06	0.00e+00	2365.00
IUUC-Cja-019656	Callithrix jacchus	94.49	0.00e+00	2391.00
IUUC-Cfa-020488	Canis familiaris	94.61	0.00e+00	2347.00
IUUC-Csa-023104	Chlorocebus sabaeus	95.81	0.00e+00	2264.00
IUUC-Cho-024379	Choloepus hoffmanni	87.85	0.00e+00	1206.00
IUUC-Dre-028836	Danio rerio	73.18	0.00e+00	1870.00
IUUC-Dno-029842	Dasypus novemcinctus	92.42	0.00e+00	2164.00
IUUC-Dor-030990	Dipodomys ordii	94.72	0.00e+00	1917.00
IUUC-Ete-032693	Echinops telfairi	84.49	0.00e+00	1932.00
IUUC-Eca-033337	Equus caballus	93.56	0.00e+00	2263.00
IUUC-Eeu-034602	Erinaceus europaeus	79.41	0.00e+00	1988.00
IUUC-Fca-035954	Felis catus	93.99	0.00e+00	1878.00
IUUC-Fal-037358	Ficedula albicollis	87.00	0.00e+00	2071.00
IUUC-Gmo-038836	Gadus morhua	78.62	0.00e+00	1770.00
IUUC-Gga-040443	Gallus gallus	85.49	0.00e+00	2202.00
IUUC-Gac-041634	Gasterosteus aculeatus	75.23	0.00e+00	1938.00
IUUC-Ggo-045263	Gorilla gorilla	93.01	0.00e+00	2328.00
IUUC-Hsa-046906	Homo sapiens	95.02	0.00e+00	2412.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	93.06	0.00e+00	1073.00
IUUC-Lch-050213	Latimeria chalumnae	78.47	0.00e+00	1801.00
IUUC-Loc-051829	Lepisosteus oculatus	74.94	0.00e+00	1865.00
IUUC-Laf-053538	Loxodonta africana	94.55	0.00e+00	2388.00
IUUC-Mcc-054776	Macaca mulatta	94.80	0.00e+00	2408.00
IUUC-Mga-059636	Meleagris gallopavo	87.29	0.00e+00	2098.00
IUUC-Mmr-061323	Microcebus murinus	94.04	0.00e+00	2340.00
IUUC-Mdo-062146	Monodelphis domestica	91.05	0.00e+00	2274.00
IUUC-Mmu-064022	Mus musculus	94.40	0.00e+00	2356.00
IUUC-Mpu-066531	Mustela putorius furo	91.23	0.00e+00	2348.00
IUUC-Mlu-068181	Myotis lucifugus	89.92	0.00e+00	2304.00
IUUC-Nle-069758	Nomascus leucogenys	95.81	0.00e+00	2263.00
IUUC-Opr-070531	Ochotona princeps	86.52	0.00e+00	1442.00
IUUC-Ont-072014	Oreochromis niloticus	77.60	0.00e+00	1907.00
IUUC-Oan-073169	Ornithorhynchus anatinus	91.76	0.00e+00	2202.00
IUUC-Ocu-074050	Oryctolagus cuniculus	90.68	0.00e+00	2115.00
IUUC-Ola-086941	Oryzias latipes	80.55	0.00e+00	1552.00
IUUC-Oga-088796	Otolemur garnettii	93.74	0.00e+00	2326.00
IUUC-Oar-090445	Ovis aries	95.01	0.00e+00	2248.00
IUUC-Ptr-090846	Pan troglodytes	95.10	0.00e+00	2412.00
IUUC-Pan-091986	Papio anubis	94.87	0.00e+00	2410.00
IUUC-Psi-093805	Pelodiscus sinensis	87.18	0.00e+00	2183.00
IUUC-Pfo-097301	Poecilia formosa	75.73	0.00e+00	1915.00
IUUC-Pab-097662	Pongo abelii	94.87	0.00e+00	2405.00
IUUC-Pca-100755	Procavia capensis	71.46	0.00e+00	708.00
IUUC-Pva-102280	Pteropus vampyrus	85.75	0.00e+00	2170.00
IUUC-Rno-105547	Rattus norvegicus	93.34	0.00e+00	2352.00
IUUC-Sha-106859	Sarcophilus harrisii	93.28	0.00e+00	2227.00
IUUC-Sar-113714	Sorex araneus	82.72	0.00e+00	1905.00
IUUC-Tgu-117116	Taeniopygia guttata	86.11	0.00e+00	2155.00
IUUC-Tru-118088	Takifugu rubripes	76.63	0.00e+00	1943.00
IUUC-Tsy-119616	Tarsius syrichta	89.46	0.00e+00	1942.00
IUUC-Tni-120284	Tetraodon nigroviridis	74.38	0.00e+00	1908.00
IUUC-Tbe-127900	Tupaia belangeri	94.68	0.00e+00	845.00
IUUC-Ttr-128294	Tursiops truncatus	83.71	0.00e+00	2064.00
IUUC-Vpa-130470	Vicugna pacos	85.03	0.00e+00	2003.00
IUUC-Xtr-132396	Xenopus tropicalis	76.22	0.00e+00	1937.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence