iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	UniProt
PHOSIDA	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
UBD/Alpha-Helix/UBA	UBA	15933713; 17028178

Classification

Family	E-value	Score	Start	End
UBD/Alpha-Helix/UBA	8.10e-10	37.0	1	40

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 1    sededkleqlveMGFdreealqaLraannnleaAveyLld 40
           ++d++++  l eMG++ e a+ aL+++++nleaAv+++++
   Q: 1    MMDNQAVKSLLEMGIPHEVAVDALQRTGGNLEAAVNFIFS 40
           789**********************************997 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Modulates the activity of the RSP5 HECT ubiquitin-protein ligase through its mediation of the interaction between RSP5 and the deubiquitinase UBP2. Involved in regulation of cell wall homeostasis.

Protein Sequence
(Fasta)

MMDNQAVKSL LEMGIPHEVA VDALQRTGGN LEAAVNFIFS NELPEQAEMG EENDGSQPRI 60
SENKIVAGTK PCDVPNNGDQ DIDMPDVSGV DVDYDDDEDI TDERSGSNST SGCRVTAQNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGGATA ATCAGGCTGT AAAGTCACTG CTAGAAATGG GTATTCCACA CGAAGTAGCT 60
GTGGACGCCC TCCAAAGAAC TGGCGGTAAT TTGGAGGCAG CAGTTAACTT CATCTTTTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50030--UBA

Pfam

PF00627--UBA

SMART

SM00165--UBA

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:1902499--P:positive regulation of protein autoubiquitination
GO:0016579--P:protein deubiquitination

KEGG

sce:YOR138C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004367	Anolis carolinensis	40.00	1.00e-03	36.60
IUUC-Ani-009194	Aspergillus nidulans	37.78	3.00e-03	35.40
IUUC-Ate-010509	Aspergillus terreus	25.56	3.10e-02	32.00
IUUC-Bci-013672	Botrytis cinerea	29.31	6.40e-02	29.60
IUUC-Csa-023299	Chlorocebus sabaeus	40.00	8.00e-04	37.00
IUUC-Gga-040195	Gallus gallus	45.00	2.00e-04	39.30
IUUC-Ggo-044715	Gorilla gorilla	40.00	7.00e-04	37.00
IUUC-Hsa-045814	Homo sapiens	40.00	9.00e-04	37.00
IUUC-Kpa-049313	Komagataella pastoris	23.82	9.00e-16	76.60
IUUC-Loc-052519	Lepisosteus oculatus	30.00	4.00e-03	33.90
IUUC-Mcc-055846	Macaca mulatta	40.00	8.00e-04	37.40
IUUC-Mpu-065705	Mustela putorius furo	28.80	1.10e-02	33.90
IUUC-Nle-069184	Nomascus leucogenys	40.00	8.00e-04	37.00
IUUC-Opr-070770	Ochotona princeps	40.00	7.00e-04	37.00
IUUC-Ont-071429	Oreochromis niloticus	35.14	5.00e-03	33.90
IUUC-Ola-087273	Oryzias latipes	22.00	6.00e-03	33.50
IUUC-Ptr-090974	Pan troglodytes	40.00	7.00e-04	37.00
IUUC-Pan-092657	Papio anubis	40.00	8.00e-04	37.00
IUUC-Psi-093113	Pelodiscus sinensis	40.00	2.00e-03	35.80
IUUC-Pab-098070	Pongo abelii	40.00	8.00e-04	37.00
IUUC-Pca-101032	Procavia capensis	42.50	3.00e-04	38.10
IUUC-Spo-108263	Schizosaccharomyces pombe	43.24	7.00e-04	37.00
IUUC-Tgu-117148	Taeniopygia guttata	41.46	4.00e-04	38.10

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence