iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073564

Ensembl Protein ID

ENSOANP00000021142.2

UniProt Accession

F7D4Y0; F7D4Y0_ORNAN

Protein Name

Uncharacterized protein

Gene Name

NOD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000013397.2	ENSOANT00000021145.2	ENSOANP00000021142.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/CARD	62.30	0.00e+00	1103.00	IUUC-Hsa-046093

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MRRTMLPPET FRAQRSQLVA QLGRGSTETF ESVLDFLLSW DVLTWEDYES VSVRGHPPSQ 60
LARRLLDIVG NKGGRSGELL VAAVREAERE VRRAGGSWER LPEASGPIWD LQRQRPAVVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCGGATTGA GACATGCGGC TGCCAGCCGC CCGGCTCCTC TGCCCGGGGC GTTAGATGCC 60
CACTCTCTAC CGACTGAGGA GCCGTGGGAC AGGAGGGCGT CCCACTGAAC GCCCGTGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase
IPR027417--P-loop_NTPase

PROSITE

PS50209--CARD
PS50837--NACHT

Pfam

PF00619--CARD
PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0009986--C:cell surface
GO:0008180--C:COP9 signalosome
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0031982--C:vesicle
GO:0005524--F:ATP binding
GO:0032500--F:muramyl dipeptide binding
GO:0042834--F:peptidoglycan binding
GO:0071225--P:cellular response to muramyl dipeptide
GO:0002374--P:cytokine secretion involved in immune response
GO:0042742--P:defense response to bacterium
GO:0016045--P:detection of bacterium
GO:0032498--P:detection of muramyl dipeptide
GO:0045087--P:innate immune response
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0070431--P:nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0050871--P:positive regulation of B cell activation
GO:1900017--P:positive regulation of cytokine production involved in inflammatory response
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050718--P:positive regulation of interleukin-1 beta secretion
GO:0032740--P:positive regulation of interleukin-17 production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:0002830--P:positive regulation of type 2 immune response
GO:0042981--P:regulation of apoptotic process

KEGG

oaa:100090933

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001822	Ailuropoda melanoleuca	62.43	0.00e+00	1065.00
IUUC-Ame-011021	Astyanax mexicanus	44.86	0.00e+00	811.00
IUUC-Bta-013241	Bos taurus	61.95	0.00e+00	1152.00
IUUC-Cja-019633	Callithrix jacchus	58.31	0.00e+00	824.00
IUUC-Cfa-020039	Canis familiaris	62.63	0.00e+00	1154.00
IUUC-Cpo-022337	Cavia porcellus	59.66	0.00e+00	1049.00
IUUC-Csa-023906	Chlorocebus sabaeus	62.30	0.00e+00	1161.00
IUUC-Dre-027568	Danio rerio	44.64	0.00e+00	757.00
IUUC-Dno-029098	Dasypus novemcinctus	63.55	0.00e+00	1086.00
IUUC-Dor-031102	Dipodomys ordii	69.25	1.00e-149	523.00
IUUC-Ete-032943	Echinops telfairi	61.69	0.00e+00	852.00
IUUC-Eca-034310	Equus caballus	63.15	0.00e+00	1125.00
IUUC-Eeu-034589	Erinaceus europaeus	68.81	1.00e-130	460.00
IUUC-Fca-036252	Felis catus	59.29	7.00e-162	564.00
IUUC-Gac-041442	Gasterosteus aculeatus	43.96	0.00e+00	731.00
IUUC-Ggo-044861	Gorilla gorilla	62.50	0.00e+00	1116.00
IUUC-Hsa-046093	Homo sapiens	62.30	0.00e+00	1113.00
IUUC-Itr-048543	Ictidomys tridecemlineatus	61.65	0.00e+00	1061.00
IUUC-Lch-049454	Latimeria chalumnae	53.59	0.00e+00	894.00
IUUC-Laf-053553	Loxodonta africana	62.01	0.00e+00	1058.00
IUUC-Mcc-055772	Macaca mulatta	62.30	0.00e+00	1147.00
IUUC-Meu-056785	Macropus eugenii	62.03	9.00e-96	344.00
IUUC-Mmr-060596	Microcebus murinus	62.79	0.00e+00	1119.00
IUUC-Mdo-062983	Monodelphis domestica	64.33	0.00e+00	1030.00
IUUC-Mmu-063951	Mus musculus	57.36	0.00e+00	1097.00
IUUC-Mpu-066412	Mustela putorius furo	61.91	0.00e+00	1125.00
IUUC-Mlu-067601	Myotis lucifugus	61.04	0.00e+00	1042.00
IUUC-Ncr-068735	Neurospora crassa	39.34	3.80e-02	33.50
IUUC-Nle-069913	Nomascus leucogenys	63.57	0.00e+00	973.00
IUUC-Opr-070999	Ochotona princeps	59.82	0.00e+00	659.00
IUUC-Ont-072512	Oreochromis niloticus	44.48	0.00e+00	814.00
IUUC-Ocu-074837	Oryctolagus cuniculus	61.52	0.00e+00	1117.00
IUUC-Ola-086555	Oryzias latipes	44.28	0.00e+00	745.00
IUUC-Oga-088909	Otolemur garnettii	62.05	0.00e+00	1102.00
IUUC-Oar-089315	Ovis aries	61.01	0.00e+00	1102.00
IUUC-Ptr-090542	Pan troglodytes	62.40	0.00e+00	1115.00
IUUC-Pan-092545	Papio anubis	62.50	0.00e+00	1147.00
IUUC-Pma-094167	Petromyzon marinus	32.39	1.00e-54	206.00
IUUC-Ppa-095344	Physcomitrella patens	25.96	7.00e-07	48.90
IUUC-Pfo-096976	Poecilia formosa	44.13	0.00e+00	782.00
IUUC-Pab-098481	Pongo abelii	62.79	0.00e+00	1118.00
IUUC-Pca-100135	Procavia capensis	60.90	0.00e+00	972.00
IUUC-Pva-102127	Pteropus vampyrus	60.96	0.00e+00	1011.00
IUUC-Rno-105783	Rattus norvegicus	58.60	0.00e+00	1053.00
IUUC-Sar-113448	Sorex araneus	56.62	0.00e+00	651.00
IUUC-Tru-118708	Takifugu rubripes	44.31	0.00e+00	724.00
IUUC-Tni-120172	Tetraodon nigroviridis	39.50	9.00e-28	116.00
IUUC-Tbe-127661	Tupaia belangeri	63.11	5.00e-170	591.00
IUUC-Ttr-128318	Tursiops truncatus	57.03	0.00e+00	966.00
IUUC-Vpa-130502	Vicugna pacos	53.95	5.00e-103	368.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence