iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044971

Ensembl Protein ID

ENSGGOP00000027940.1

UniProt Accession

G3SIK0; G3SIK0_GORGO

Protein Name

Uncharacterized protein

Gene Name

TNIP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000025865.1	ENSGGOT00000023131.1	ENSGGOP00000027940.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	1.50e-23	82.9	290	346

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndsl 57
           ++++le+v++L+qQ+ +Yk+DF++ERadREr++++++eL+e+v++l++qvs+++ds+
   Q: 290  RDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSR 346
           6899***************************************************97 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

AMSRDPGSGG WEGAPRAAAA LCTLYHEAGQ RLRRLQDQLA ARDALIARLR ARLAALEGDA 60
APSLVDALLE QVARFREQLR RQEGGAAEAQ MRQEIERLTE RLEEKEREMQ QLLSQPQHER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCGGGAAG GGCGGAGAGC GAGTGCCCGC CGCAGCCTTT GAGTCTTGTG GGGAGGGTCG 60
CGTAAAGGGG CCCCGCGGCG GGGCCAGAGG GGCGCGACGG GTGCGAAACA GACGCGTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR022008--EABR
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF12180--EABR

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0023035--P:CD40 signaling pathway
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:2000352--P:negative regulation of endothelial cell apoptotic process
GO:0050871--P:positive regulation of B cell activation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043032--P:positive regulation of macrophage activation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0050821--P:protein stabilization
GO:0034134--P:toll-like receptor 2 signaling pathway
GO:0034138--P:toll-like receptor 3 signaling pathway
GO:0034162--P:toll-like receptor 9 signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001697	Ailuropoda melanoleuca	73.75	1.00e-137	482.00
IUUC-Apl-003896	Anas platyrhynchos	47.13	5.00e-96	344.00
IUUC-Ame-011223	Astyanax mexicanus	35.35	7.00e-45	174.00
IUUC-Bta-012996	Bos taurus	76.85	2.00e-135	474.00
IUUC-Cja-019376	Callithrix jacchus	86.54	2.00e-166	578.00
IUUC-Cfa-021027	Canis familiaris	71.26	2.00e-151	528.00
IUUC-Cpo-021372	Cavia porcellus	69.76	7.00e-118	417.00
IUUC-Csa-023221	Chlorocebus sabaeus	96.74	0.00e+00	709.00
IUUC-Dre-028604	Danio rerio	34.61	1.00e-49	190.00
IUUC-Dno-029976	Dasypus novemcinctus	65.45	6.00e-53	200.00
IUUC-Dor-030364	Dipodomys ordii	60.25	1.00e-61	230.00
IUUC-Eca-033582	Equus caballus	81.82	9.00e-160	556.00
IUUC-Eeu-034751	Erinaceus europaeus	68.57	3.00e-64	237.00
IUUC-Fca-036086	Felis catus	76.16	5.00e-132	463.00
IUUC-Fal-036828	Ficedula albicollis	47.45	1.00e-100	360.00
IUUC-Gmo-038838	Gadus morhua	37.17	2.00e-46	179.00
IUUC-Gga-041179	Gallus gallus	45.59	2.00e-98	353.00
IUUC-Gac-042266	Gasterosteus aculeatus	35.25	6.00e-40	158.00
IUUC-Hsa-045772	Homo sapiens	98.60	0.00e+00	686.00
IUUC-Itr-048993	Ictidomys tridecemlineatus	77.45	3.00e-137	480.00
IUUC-Lch-049851	Latimeria chalumnae	39.35	2.00e-64	239.00
IUUC-Loc-052551	Lepisosteus oculatus	37.33	5.00e-57	214.00
IUUC-Laf-053650	Loxodonta africana	58.39	2.00e-88	318.00
IUUC-Mcc-054744	Macaca mulatta	96.74	0.00e+00	726.00
IUUC-Meu-056799	Macropus eugenii	55.70	6.00e-37	147.00
IUUC-Mga-060124	Meleagris gallopavo	47.99	7.00e-92	330.00
IUUC-Mmr-061466	Microcebus murinus	87.09	2.00e-164	571.00
IUUC-Mdo-062389	Monodelphis domestica	56.31	2.00e-115	409.00
IUUC-Mmu-064000	Mus musculus	75.50	3.00e-160	558.00
IUUC-Mpu-066109	Mustela putorius furo	78.15	1.00e-166	579.00
IUUC-Mlu-067666	Myotis lucifugus	68.88	8.00e-75	273.00
IUUC-Nle-069689	Nomascus leucogenys	95.58	2.00e-177	614.00
IUUC-Opr-070774	Ochotona princeps	60.82	7.00e-76	276.00
IUUC-Ont-072439	Oreochromis niloticus	37.08	1.00e-55	210.00
IUUC-Oan-072817	Ornithorhynchus anatinus	54.55	8.00e-62	229.00
IUUC-Ocu-074621	Oryctolagus cuniculus	67.35	8.00e-88	316.00
IUUC-Ola-087305	Oryzias latipes	37.58	3.00e-51	196.00
IUUC-Oga-087920	Otolemur garnettii	78.27	2.00e-152	532.00
IUUC-Oar-090351	Ovis aries	64.58	9.00e-20	87.40
IUUC-Ptr-090879	Pan troglodytes	99.17	2.00e-128	451.00
IUUC-Pan-092022	Papio anubis	96.97	0.00e+00	711.00
IUUC-Psi-093302	Pelodiscus sinensis	46.09	8.00e-101	360.00
IUUC-Pno-095083	Phaeosphaeria nodorum	24.82	4.00e-04	40.80
IUUC-Pfo-097250	Poecilia formosa	35.76	8.00e-47	181.00
IUUC-Pab-097929	Pongo abelii	97.83	0.00e+00	640.00
IUUC-Pca-100271	Procavia capensis	70.39	2.00e-44	172.00
IUUC-Pva-102234	Pteropus vampyrus	71.22	3.00e-122	431.00
IUUC-Rno-105850	Rattus norvegicus	77.80	2.00e-174	605.00
IUUC-Sha-107375	Sarcophilus harrisii	54.98	2.00e-96	346.00
IUUC-Ssc-116269	Sus scrofa	79.57	4.00e-152	531.00
IUUC-Tgu-116960	Taeniopygia guttata	51.70	2.00e-98	352.00
IUUC-Tru-118002	Takifugu rubripes	33.48	1.00e-45	177.00
IUUC-Tni-120023	Tetraodon nigroviridis	35.59	8.00e-49	187.00
IUUC-Tre-121983	Trichoderma reesei	34.21	2.10e-02	33.10
IUUC-Tbe-127592	Tupaia belangeri	74.94	3.00e-147	514.00
IUUC-Ttr-128362	Tursiops truncatus	71.81	6.00e-122	430.00
IUUC-Vpa-130399	Vicugna pacos	75.07	2.00e-129	454.00
IUUC-Xtr-132677	Xenopus tropicalis	44.80	2.00e-79	289.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence