iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027492

Ensembl Protein ID

ENSDARP00000002944.8

UniProt Accession

B8JIA4; B8JIA4_DANRE

Genbank Protein ID

ENSDARP00000002944

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

CR556722

Gene Name

whsc1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000026225.9	ENSDART00000009499.8	ENSDARP00000002944.8

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.20e-13	50.6	925	966

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           +C +C +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Crs
   Q: 925  WCFICSKGGR----LLCCESCPAAFHPDCLNIA----MPDGS-WFCNDCRS 966
           8*********....*******************....9***8.******96 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MTDSKGGSLP AMPEPKSPTS MKQLSDSPGG RNGLVDGITD PTMLMNKAAT QLAATPQESV 60
PQMIGSHGHN HTHEHLKDLT SRLLNGDTEK IPKLCAAPAG QPLLKGVEPV SQHASPPRKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACGTCAGAT GGTGAGAATT GCCCTCCTCA ATTCCTCGAG CAGTGATCTG TGTCGCTTTG 60
CCATTTTTTG AAATAAAAAC AAAAACAGGT GATCTGAGAA TTGCATGGCT TTGTCTGTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0051216--P:cartilage development
GO:0048706--P:embryonic skeletal system development
GO:0010452--P:histone H3-K36 methylation

KEGG

dre:100000709

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002181	Ailuropoda melanoleuca	70.77	0.00e+00	1056.00
IUUC-Apl-003677	Anas platyrhynchos	72.48	0.00e+00	1104.00
IUUC-Aca-004278	Anolis carolinensis	72.13	0.00e+00	1082.00
IUUC-Ame-011932	Astyanax mexicanus	62.89	0.00e+00	1719.00
IUUC-Bta-012522	Bos taurus	70.86	0.00e+00	1049.00
IUUC-Cja-018908	Callithrix jacchus	70.93	0.00e+00	1047.00
IUUC-Cfa-020894	Canis familiaris	70.62	0.00e+00	1062.00
IUUC-Cpo-021982	Cavia porcellus	71.47	0.00e+00	1058.00
IUUC-Csa-023807	Chlorocebus sabaeus	70.88	0.00e+00	1050.00
IUUC-Cho-024405	Choloepus hoffmanni	74.84	5.00e-75	276.00
IUUC-Dor-031103	Dipodomys ordii	62.98	0.00e+00	909.00
IUUC-Ete-032488	Echinops telfairi	65.53	0.00e+00	916.00
IUUC-Eca-034066	Equus caballus	70.77	0.00e+00	1055.00
IUUC-Eeu-035199	Erinaceus europaeus	54.60	9.00e-114	405.00
IUUC-Fca-035434	Felis catus	67.04	0.00e+00	1008.00
IUUC-Fal-037113	Ficedula albicollis	70.68	0.00e+00	1112.00
IUUC-Gmo-039686	Gadus morhua	76.45	0.00e+00	1122.00
IUUC-Gga-040273	Gallus gallus	72.29	0.00e+00	1107.00
IUUC-Gac-042123	Gasterosteus aculeatus	76.83	0.00e+00	1193.00
IUUC-Ggo-044643	Gorilla gorilla	70.17	0.00e+00	1053.00
IUUC-Hsa-046380	Homo sapiens	71.03	0.00e+00	1049.00
IUUC-Itr-048658	Ictidomys tridecemlineatus	68.81	0.00e+00	1031.00
IUUC-Lch-050217	Latimeria chalumnae	69.89	0.00e+00	1111.00
IUUC-Loc-052766	Lepisosteus oculatus	77.93	0.00e+00	1189.00
IUUC-Laf-053780	Loxodonta africana	70.46	0.00e+00	1054.00
IUUC-Mcc-054928	Macaca mulatta	70.03	0.00e+00	1052.00
IUUC-Mla-059157	Melampsora laricipopulina	36.36	1.00e+00	27.30
IUUC-Mga-059576	Meleagris gallopavo	72.19	0.00e+00	1098.00
IUUC-Mmr-061045	Microcebus murinus	69.94	0.00e+00	1063.00
IUUC-Mdo-062576	Monodelphis domestica	71.61	0.00e+00	1084.00
IUUC-Mmu-063640	Mus musculus	69.97	0.00e+00	1056.00
IUUC-Mac-065303	Musa acuminata	28.57	3.00e-12	67.00
IUUC-Mpu-066512	Mustela putorius furo	71.06	0.00e+00	1060.00
IUUC-Nle-069896	Nomascus leucogenys	70.56	0.00e+00	979.00
IUUC-Ont-072197	Oreochromis niloticus	82.40	0.00e+00	1173.00
IUUC-Ocu-074758	Oryctolagus cuniculus	70.76	0.00e+00	1046.00
IUUC-Olo-080702	Oryza longistaminata	40.00	5.00e-44	173.00
IUUC-Oar-089736	Ovis aries	71.92	0.00e+00	942.00
IUUC-Ptr-091055	Pan troglodytes	71.03	0.00e+00	1050.00
IUUC-Pan-092752	Papio anubis	71.18	0.00e+00	1034.00
IUUC-Psi-093620	Pelodiscus sinensis	72.87	0.00e+00	1113.00
IUUC-Pfo-097464	Poecilia formosa	76.41	0.00e+00	1187.00
IUUC-Pab-098051	Pongo abelii	70.17	0.00e+00	1053.00
IUUC-Pop-099927	Populus trichocarpa	29.32	2.00e-12	67.80
IUUC-Pca-100273	Procavia capensis	70.83	0.00e+00	1042.00
IUUC-Pva-102473	Pteropus vampyrus	69.91	0.00e+00	930.00
IUUC-Rno-105056	Rattus norvegicus	66.89	0.00e+00	1052.00
IUUC-Sha-107494	Sarcophilus harrisii	71.47	0.00e+00	1078.00
IUUC-Sar-113310	Sorex araneus	69.57	0.00e+00	914.00
IUUC-Ssc-116344	Sus scrofa	68.16	0.00e+00	1047.00
IUUC-Tgu-116786	Taeniopygia guttata	72.37	0.00e+00	1102.00
IUUC-Tru-117638	Takifugu rubripes	77.06	0.00e+00	1190.00
IUUC-Tsy-118937	Tarsius syrichta	69.71	0.00e+00	1047.00
IUUC-Tni-120452	Tetraodon nigroviridis	60.68	0.00e+00	1361.00
IUUC-Tbe-127291	Tupaia belangeri	67.74	0.00e+00	993.00
IUUC-Xtr-132673	Xenopus tropicalis	67.12	0.00e+00	1031.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence