iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-089086

Ensembl Protein ID

ENSOGAP00000001067.2

UniProt Accession

H0WI33; H0WI33_OTOGA

Genbank Protein ID

ENSOGAP00000001067

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03133126

Gene Name

RNF135

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000001193.2	ENSOGAT00000001194.2	ENSOGAP00000001067.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.80e-06	26.7	21	61

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC+  +++ p +lpCgH f+++Cl+++      ++++  CP+Cr
   Q: 21   CIICHGLLDC-PTTLPCGHSFCRSCLKRL----WTARRHRDCPTCR 61
           ********99.999************666....58999999****8 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAGLDSGLAV PVWLAEDDLG CIICHGLLDC PTTLPCGHSF CRSCLKRLWT ARRHRDCPTC 60
REGAAQQPRL QKNTLLQELV DKYKRAAREL QAGPSPAPAA GSAPAPAPAR EAVQNNIMKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGGTC TGGACTCCGG CCTGGCGGTC CCGGTGTGGC TGGCCGAGGA CGACCTGGGC 60
TGCATCATCT GCCATGGCCT GCTGGACTGT CCCACCACGC TGCCCTGCGG CCACAGCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0043021--F:ribonucleoprotein complex binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0032728--P:positive regulation of interferon-beta production
GO:0045088--P:regulation of innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002251	Ailuropoda melanoleuca	68.17	5.00e-116	410.00
IUUC-Apl-003301	Anas platyrhynchos	44.86	3.00e-39	154.00
IUUC-Aca-004520	Anolis carolinensis	38.67	8.00e-35	139.00
IUUC-Bta-012846	Bos taurus	63.29	4.00e-141	494.00
IUUC-Cja-019096	Callithrix jacchus	70.19	1.00e-153	536.00
IUUC-Cfa-020135	Canis familiaris	62.16	1.00e-133	469.00
IUUC-Cpo-022042	Cavia porcellus	53.59	4.00e-110	391.00
IUUC-Csa-024154	Chlorocebus sabaeus	69.20	6.00e-163	566.00
IUUC-Cho-024619	Choloepus hoffmanni	63.40	2.00e-100	358.00
IUUC-Dno-028856	Dasypus novemcinctus	65.69	1.00e-138	486.00
IUUC-Eca-033795	Equus caballus	64.79	3.00e-141	494.00
IUUC-Eeu-035078	Erinaceus europaeus	58.51	2.00e-132	465.00
IUUC-Fca-035503	Felis catus	72.68	3.00e-85	307.00
IUUC-Fal-036914	Ficedula albicollis	47.73	9.00e-32	128.00
IUUC-Ggo-045197	Gorilla gorilla	70.75	6.00e-140	489.00
IUUC-Hsa-046550	Homo sapiens	72.45	3.00e-172	597.00
IUUC-Itr-049007	Ictidomys tridecemlineatus	58.48	5.00e-139	487.00
IUUC-Laf-053812	Loxodonta africana	68.91	1.00e-158	552.00
IUUC-Mcc-055777	Macaca mulatta	69.89	1.00e-163	568.00
IUUC-Meu-056473	Macropus eugenii	54.19	2.00e-49	189.00
IUUC-Mmr-061016	Microcebus murinus	74.94	2.00e-168	585.00
IUUC-Mmu-063129	Mus musculus	58.71	2.00e-129	455.00
IUUC-Mpu-065938	Mustela putorius furo	67.78	2.00e-142	498.00
IUUC-Mlu-067911	Myotis lucifugus	57.44	3.00e-133	468.00
IUUC-Opr-071118	Ochotona princeps	57.35	5.00e-83	300.00
IUUC-Oan-073277	Ornithorhynchus anatinus	38.02	2.00e-63	236.00
IUUC-Ocu-074512	Oryctolagus cuniculus	67.55	1.00e-113	402.00
IUUC-Oar-089493	Ovis aries	70.17	4.00e-91	327.00
IUUC-Ptr-090466	Pan troglodytes	72.64	1.00e-166	578.00
IUUC-Pan-091817	Papio anubis	70.11	5.00e-164	570.00
IUUC-Psi-093151	Pelodiscus sinensis	36.30	9.00e-46	177.00
IUUC-Pab-098342	Pongo abelii	72.45	3.00e-171	594.00
IUUC-Pca-101052	Procavia capensis	58.27	3.00e-70	258.00
IUUC-Pva-103178	Pteropus vampyrus	68.75	1.00e-115	410.00
IUUC-Rno-105519	Rattus norvegicus	60.67	1.00e-128	453.00
IUUC-Ssc-115925	Sus scrofa	64.78	9.00e-149	520.00
IUUC-Tgu-116757	Taeniopygia guttata	46.97	3.00e-31	127.00
IUUC-Ttr-128972	Tursiops truncatus	53.53	8.00e-57	213.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence