iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090519

UUCD1 version

UUC-PaT-00611

Ensembl Protein ID

ENSPTRP00000030382.3

UniProt Accession

H2QSE9; H2QSE9_PANTR

Genbank Protein ID

JAA04162.1; JAA13839.1; JAA22815.1; JAA36161.1

Protein Name

Tripartite motif containing 38

Genbank Nucleotide ID

AACZ03046560; GABF01008306; GABD01010285; GABE01008578

Gene Name

TRIM38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000017795.4	ENSPTRT00000032882.3	ENSPTRP00000030382.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.80e-08	34.3	11	83

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk........tcPvtrqplteedlvPnltlrrliqa 67
            ee  C+I l lM++Pv + +G++y   +I  ++++  +         cP +r+p++ ++l Pn+ l +li+a
   Q: 11   MEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQkqlrqetfCCPQCRAPFHMDSLRPNKQLGSLIEA 83
           68899*****************************55555578899999*******************999987 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MASTTSTKKM MEEATCSICL SLMTNPVSIN CGHSYCHLCI TDFFKNPSQK QLRQETFCCP 60
QCRAPFHMDS LRPNKQLGSL IEALKEMDQE MSCEEHGEQL HLFCEDEGQL ICWRCERAPQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACTTTACA CCAAATCTCA GAAGATTCAG AAGTTAGATG AGTGGGGCCC AGGACAGGAA 60
CCCTGGAGCC TTGGAAGGAG GTGAGCCCCA TCTCCCTAGA AGTGCAGTGA CCCCAGCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004871--F:signal transducer activity
GO:0008270--F:zinc ion binding
GO:0050687--P:negative regulation of defense response to virus
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046598--P:positive regulation of viral entry into host cell
GO:0045070--P:positive regulation of viral genome replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0032648--P:regulation of interferon-beta production

KEGG

ptr:471873

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001649	Ailuropoda melanoleuca	73.06	0.00e+00	716.00
IUUC-Ago-007781	Ashbya gossypii	37.93	1.00e-10	61.20
IUUC-Bta-012574	Bos taurus	76.52	0.00e+00	733.00
IUUC-Cja-019759	Callithrix jacchus	89.03	0.00e+00	814.00
IUUC-Cfa-020431	Canis familiaris	71.40	0.00e+00	679.00
IUUC-Cpo-022541	Cavia porcellus	66.88	0.00e+00	649.00
IUUC-Csa-023320	Chlorocebus sabaeus	94.62	0.00e+00	921.00
IUUC-Cho-024964	Choloepus hoffmanni	70.43	6.00e-130	456.00
IUUC-Dno-029741	Dasypus novemcinctus	66.88	3.00e-179	620.00
IUUC-Dor-030298	Dipodomys ordii	60.68	5.00e-102	363.00
IUUC-Ete-032493	Echinops telfairi	66.38	2.00e-180	624.00
IUUC-Eca-033962	Equus caballus	77.42	0.00e+00	726.00
IUUC-Eeu-035228	Erinaceus europaeus	67.18	9.00e-128	449.00
IUUC-Fca-036349	Felis catus	73.65	0.00e+00	709.00
IUUC-Ggo-044493	Gorilla gorilla	98.28	0.00e+00	952.00
IUUC-Hsa-046161	Homo sapiens	98.92	0.00e+00	960.00
IUUC-Itr-048162	Ictidomys tridecemlineatus	60.82	9.00e-150	523.00
IUUC-Laf-054150	Loxodonta africana	74.62	0.00e+00	706.00
IUUC-Mcc-055076	Macaca mulatta	94.62	0.00e+00	922.00
IUUC-Mmu-063517	Mus musculus	55.86	4.00e-146	511.00
IUUC-Mpu-065752	Mustela putorius furo	72.20	0.00e+00	703.00
IUUC-Mlu-067758	Myotis lucifugus	59.50	1.00e-150	526.00
IUUC-Nle-069117	Nomascus leucogenys	95.70	0.00e+00	927.00
IUUC-Opr-071144	Ochotona princeps	68.39	0.00e+00	638.00
IUUC-Ocu-074825	Oryctolagus cuniculus	70.54	0.00e+00	690.00
IUUC-Oga-088744	Otolemur garnettii	75.25	1.00e-129	455.00
IUUC-Oar-089951	Ovis aries	75.87	0.00e+00	729.00
IUUC-Pan-092059	Papio anubis	94.62	0.00e+00	924.00
IUUC-Pab-098747	Pongo abelii	96.99	0.00e+00	944.00
IUUC-Pca-100294	Procavia capensis	68.39	0.00e+00	663.00
IUUC-Pva-102129	Pteropus vampyrus	66.59	0.00e+00	645.00
IUUC-Sar-113760	Sorex araneus	63.64	1.00e-156	545.00
IUUC-Tsy-119422	Tarsius syrichta	77.20	0.00e+00	721.00
IUUC-Tbe-127628	Tupaia belangeri	63.89	9.00e-102	362.00
IUUC-Ttr-129039	Tursiops truncatus	77.63	0.00e+00	748.00
IUUC-Vpa-130188	Vicugna pacos	78.84	8.00e-137	479.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence