iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052366

Ensembl Protein ID

ENSLOCP00000016220.1

UniProt Accession

W5N6G1; W5N6G1_LEPOC

Genbank Protein ID

ENSLOCP00000016220

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01000412

Gene Name

FBXW10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000013166.1	ENSLOCT00000016250.1	ENSLOCP00000016220.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-32	109.1	486	519
UBD/Beta-Prp	7.20e-46	156.9	413	620

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           gH + ++cl++++++lvsG+ D+++kvW+l tg+
   Q: 486  GHLGTISCLDLHGNRLVSGAKDCKVKVWNLLTGK 519
           8**********559***************98885 PP

UBD/Beta-Prp

   S: 62   pdgkilvtgseDrtikvwdlstgkcvh.tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg 149
           + gk+ + gs+Dr +++ dl +gk v   ++gh  s++++ +++++ +++s+s d  ir+w+l+tg c++ +++gh g+++c+ +h+  
   Q: 413  NGGKMVAIGSKDRQVRLLDLANGKEVPpLIHGHAGSIRAVLLCEERGFVISASYDLSIRCWNLQTGACMK-IFRGHLGTISCLDLHG-- 498
           556799***************9998871556***************************************.****************.. PP
   S: 150  nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlv 238
           n lvsG++D +v++W+l tgk  ++l+ +h+d++ ++++d+   ++vsg ++g vk+w ++tg  ++t++gh+  vk++ f+  + +++
   Q: 499  NRLVSGAKDCKVKVWNLLTGKNFTKLKFKHQDPILCVKIDK--SYVVSGCRKGLVKVWHIETGCLMKTVEGHQGAVKCLFFD--QWHIL 583
           *****************************************..7*************************************9..99*** PP
   S: 239  sgssDgsiriW..dlrsgdllktlqlhnssvisvavls 274
           sg+sDg i  W  +++ + +l ++ +++  v + a+l+
   Q: 584  SGGSDGYIMAWsmNKEFQRCLMAFRHPK-EVQCLAFLY 620
           ***********99999999999999988.677776665 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

KERHEFRIDA AHELRCGSGD SAVRFCGSCE ACRFNSRLSA ATRWFTRAGD ASKRRFLTGL 60
ILRCQSLDLL VNTQKVLQVT LGKDFTYSRS RAAPSLDQDS TTWSADRALD SRLLGREMLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGGAGCGTC ATGAATTTCG GATCGACGCG GCGCATGAGC TGAGGTGCGG GAGCGGGGAC 60
TCCGCCGTCA GGTTTTGCGG CTCCTGCGAA GCCTGCAGGT TCAACTCCCG GCTGTCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001837	Ailuropoda melanoleuca	51.73	2.00e-113	403.00
IUUC-Apl-003572	Anas platyrhynchos	53.39	1.00e-135	477.00
IUUC-Aca-004297	Anolis carolinensis	41.03	2.00e-159	556.00
IUUC-Ame-011058	Astyanax mexicanus	49.32	0.00e+00	683.00
IUUC-Bta-012667	Bos taurus	49.45	4.00e-113	402.00
IUUC-Cja-019163	Callithrix jacchus	34.77	1.00e-177	617.00
IUUC-Cfa-020784	Canis familiaris	35.35	0.00e+00	661.00
IUUC-Cpo-021429	Cavia porcellus	48.78	5.00e-109	389.00
IUUC-Csa-023597	Chlorocebus sabaeus	42.64	8.00e-160	556.00
IUUC-Cho-024559	Choloepus hoffmanni	32.09	2.00e-67	250.00
IUUC-Dre-027496	Danio rerio	55.73	4.00e-149	521.00
IUUC-Dno-028995	Dasypus novemcinctus	35.77	0.00e+00	639.00
IUUC-Ete-032823	Echinops telfairi	48.39	2.00e-51	197.00
IUUC-Eca-033666	Equus caballus	38.25	7.00e-158	551.00
IUUC-Fca-035589	Felis catus	35.86	0.00e+00	658.00
IUUC-Fal-037403	Ficedula albicollis	36.80	4.00e-135	475.00
IUUC-Gmo-038669	Gadus morhua	43.00	3.00e-110	392.00
IUUC-Gga-041227	Gallus gallus	50.10	7.00e-138	484.00
IUUC-Hsa-046221	Homo sapiens	42.65	8.00e-171	594.00
IUUC-Itr-049011	Ictidomys tridecemlineatus	41.03	1.00e-161	563.00
IUUC-Lch-050046	Latimeria chalumnae	39.91	0.00e+00	751.00
IUUC-Laf-053745	Loxodonta africana	34.52	0.00e+00	632.00
IUUC-Mcc-054826	Macaca mulatta	35.57	0.00e+00	638.00
IUUC-Meu-056636	Macropus eugenii	53.85	5.00e-28	120.00
IUUC-Mga-060185	Meleagris gallopavo	39.85	4.00e-153	535.00
IUUC-Mdo-062382	Monodelphis domestica	36.37	2.00e-174	606.00
IUUC-Mmu-063623	Mus musculus	37.19	0.00e+00	667.00
IUUC-Mpu-066872	Mustela putorius furo	51.66	3.00e-139	489.00
IUUC-Mlu-067552	Myotis lucifugus	51.13	8.00e-106	378.00
IUUC-Nle-069247	Nomascus leucogenys	42.80	2.00e-170	592.00
IUUC-Opr-070455	Ochotona princeps	51.37	1.00e-112	400.00
IUUC-Ont-071926	Oreochromis niloticus	43.48	5.00e-134	472.00
IUUC-Oan-073411	Ornithorhynchus anatinus	36.49	6.00e-144	505.00
IUUC-Ocu-073893	Oryctolagus cuniculus	39.62	4.00e-163	569.00
IUUC-Oga-087937	Otolemur garnettii	44.28	4.00e-113	402.00
IUUC-Oar-089680	Ovis aries	34.82	0.00e+00	636.00
IUUC-Ptr-091549	Pan troglodytes	39.37	2.00e-147	516.00
IUUC-Pan-091904	Papio anubis	35.65	0.00e+00	643.00
IUUC-Psi-093181	Pelodiscus sinensis	39.55	0.00e+00	723.00
IUUC-Pma-094711	Petromyzon marinus	52.96	3.00e-93	335.00
IUUC-Pab-098067	Pongo abelii	35.53	0.00e+00	643.00
IUUC-Pca-100867	Procavia capensis	35.43	1.00e-98	353.00
IUUC-Pva-102209	Pteropus vampyrus	40.74	1.00e-155	543.00
IUUC-Rno-105374	Rattus norvegicus	36.03	5.00e-170	591.00
IUUC-Sha-107459	Sarcophilus harrisii	33.67	1.00e-67	250.00
IUUC-Tgu-117261	Taeniopygia guttata	45.60	1.00e-101	363.00
IUUC-Tru-117705	Takifugu rubripes	49.69	1.00e-47	181.00
IUUC-Tni-120365	Tetraodon nigroviridis	53.49	5.00e-50	190.00
IUUC-Tbe-128015	Tupaia belangeri	39.33	1.00e-140	494.00
IUUC-Ttr-128654	Tursiops truncatus	40.49	1.00e-155	543.00
IUUC-Vpa-130176	Vicugna pacos	33.65	8.00e-108	384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence