iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000007113.1	ENSSHAT00000008273.1	ENSSHAP00000008206.1
ENSSHAG00000007113.1	ENSSHAT00000008274.1	ENSSHAP00000008207.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.50e-22	77.0	242	305

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++e++qv+y+y++qnddeL+l  Gd++++   e+++++egW++g++ ++g++Gl+Pen+++k++
   Q: 242  NHETLQVIYPYTPQNDDELELVPGDFIFMSpmEQTSTSEGWIYGTSLTTGCSGLLPENYITKAD 305
           6899*********************************************************987 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

VALGKDLAGN LSLSVNRGPQ TPPLHSALGA MGKKADVRQK ALASTGGRSV QAACDWLYRL 60
FSHVGDPFLD DSLPREYVLY LRPTGPLAQK LSDFWQQSKQ ICGKNKAHNI FPHITLCQFF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAATCCT GCCTCCCTTC CAAGGGAGTG AATCAGTAAG TGAGGTGGTT ACAAAAGAAA 60
GGGACTTTAA GAAATCATCA CTTCCTTTTA TAGGGGAGAA AACAAAGGTC TATAAAAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009097--cNuc_Pdiesterase
IPR013078--His_Pase_superF_clade-1
IPR029033--His_PPase_superfam
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00300--His_Phos_1
PF14604--SH3_9

SMART

SM00326--SH3

Gene Ontology

GO:0004725--F:protein tyrosine phosphatase activity
GO:0045779--P:negative regulation of bone resorption
GO:0045671--P:negative regulation of osteoclast differentiation
GO:0090331--P:negative regulation of platelet aggregation
GO:0006469--P:negative regulation of protein kinase activity
GO:0009968--P:negative regulation of signal transduction
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002126	Ailuropoda melanoleuca	87.38	0.00e+00	1077.00
IUUC-Apl-004080	Anas platyrhynchos	85.41	0.00e+00	1030.00
IUUC-Aca-004828	Anolis carolinensis	82.48	0.00e+00	1020.00
IUUC-Ame-011030	Astyanax mexicanus	70.30	0.00e+00	788.00
IUUC-Bgr-012101	Blumeria graminis	28.86	4.00e-10	58.50
IUUC-Bta-012370	Bos taurus	88.85	0.00e+00	1080.00
IUUC-Bci-013728	Botrytis cinerea	28.18	1.00e-09	57.00
IUUC-Cel-018530	Caenorhabditis elegans	38.52	4.00e-50	191.00
IUUC-Cja-018758	Callithrix jacchus	88.19	0.00e+00	1084.00
IUUC-Cfa-020544	Canis familiaris	88.42	0.00e+00	922.00
IUUC-Cpo-022044	Cavia porcellus	88.45	0.00e+00	1074.00
IUUC-Csa-024169	Chlorocebus sabaeus	87.70	0.00e+00	1078.00
IUUC-Cho-024498	Choloepus hoffmanni	71.12	0.00e+00	801.00
IUUC-Cin-025372	Ciona intestinalis	38.65	1.00e-58	220.00
IUUC-Cgl-026592	Colletotrichum gloeosporioides	29.08	9.00e-09	54.30
IUUC-Dre-027539	Danio rerio	70.89	0.00e+00	895.00
IUUC-Dno-029808	Dasypus novemcinctus	81.51	2.00e-171	595.00
IUUC-Dor-030582	Dipodomys ordii	93.67	6.00e-135	474.00
IUUC-Dme-032201	Drosophila melanogaster	39.35	3.00e-59	223.00
IUUC-Ete-032740	Echinops telfairi	72.41	0.00e+00	836.00
IUUC-Eca-033743	Equus caballus	88.34	0.00e+00	1081.00
IUUC-Eeu-034505	Erinaceus europaeus	74.00	2.00e-171	595.00
IUUC-Fca-036519	Felis catus	87.54	0.00e+00	1082.00
IUUC-Fal-037295	Ficedula albicollis	84.38	0.00e+00	1028.00
IUUC-Gmo-038650	Gadus morhua	69.74	0.00e+00	843.00
IUUC-Gga-040179	Gallus gallus	84.50	0.00e+00	1040.00
IUUC-Gac-042180	Gasterosteus aculeatus	68.68	0.00e+00	838.00
IUUC-Ggo-044581	Gorilla gorilla	87.86	0.00e+00	1080.00
IUUC-Hsa-046526	Homo sapiens	87.70	0.00e+00	1080.00
IUUC-Itr-048502	Ictidomys tridecemlineatus	95.52	2.00e-158	551.00
IUUC-Lch-049576	Latimeria chalumnae	76.27	0.00e+00	953.00
IUUC-Loc-051854	Lepisosteus oculatus	74.50	0.00e+00	875.00
IUUC-Laf-054177	Loxodonta africana	86.93	0.00e+00	1071.00
IUUC-Mcc-055185	Macaca mulatta	87.70	0.00e+00	1079.00
IUUC-Meu-056216	Macropus eugenii	87.07	0.00e+00	946.00
IUUC-Mga-059564	Meleagris gallopavo	85.22	0.00e+00	1031.00
IUUC-Mmr-060934	Microcebus murinus	87.54	0.00e+00	1079.00
IUUC-Mdo-062955	Monodelphis domestica	89.58	0.00e+00	1090.00
IUUC-Mmu-063301	Mus musculus	87.22	0.00e+00	1080.00
IUUC-Mpu-066416	Mustela putorius furo	87.60	0.00e+00	1080.00
IUUC-Mlu-067833	Myotis lucifugus	86.81	0.00e+00	1021.00
IUUC-Nle-069367	Nomascus leucogenys	87.22	0.00e+00	1073.00
IUUC-Opr-070879	Ochotona princeps	76.54	0.00e+00	697.00
IUUC-Ont-072540	Oreochromis niloticus	69.49	0.00e+00	850.00
IUUC-Oan-073124	Ornithorhynchus anatinus	82.96	0.00e+00	810.00
IUUC-Ocu-074796	Oryctolagus cuniculus	87.38	0.00e+00	1076.00
IUUC-Ola-087253	Oryzias latipes	68.78	0.00e+00	846.00
IUUC-Oga-088406	Otolemur garnettii	88.89	0.00e+00	1082.00
IUUC-Oar-090262	Ovis aries	87.60	0.00e+00	1079.00
IUUC-Ptr-091014	Pan troglodytes	87.86	0.00e+00	1080.00
IUUC-Pan-092684	Papio anubis	87.70	0.00e+00	1079.00
IUUC-Psi-093541	Pelodiscus sinensis	84.33	0.00e+00	1041.00
IUUC-Pma-094108	Petromyzon marinus	57.26	3.00e-156	545.00
IUUC-Pfo-097119	Poecilia formosa	68.35	0.00e+00	811.00
IUUC-Pab-097724	Pongo abelii	86.45	0.00e+00	1055.00
IUUC-Pca-100645	Procavia capensis	74.13	0.00e+00	701.00
IUUC-Pva-102322	Pteropus vampyrus	88.45	0.00e+00	1075.00
IUUC-Rno-105148	Rattus norvegicus	86.87	0.00e+00	1075.00
IUUC-Ssl-108385	Sclerotinia sclerotiorum	30.36	1.00e-08	53.50
IUUC-Sar-113746	Sorex araneus	73.01	3.00e-93	334.00
IUUC-Ssc-116425	Sus scrofa	88.01	0.00e+00	1080.00
IUUC-Tgu-116520	Taeniopygia guttata	82.87	0.00e+00	1015.00
IUUC-Tru-117750	Takifugu rubripes	64.50	0.00e+00	800.00
IUUC-Tsy-118975	Tarsius syrichta	88.58	0.00e+00	1054.00
IUUC-Tni-119830	Tetraodon nigroviridis	69.74	0.00e+00	822.00
IUUC-Ttr-129103	Tursiops truncatus	87.11	0.00e+00	1079.00
IUUC-Uma-129616	Ustilago maydis	24.39	8.00e-06	43.90
IUUC-Vpa-130720	Vicugna pacos	95.92	2.00e-112	399.00
IUUC-Xtr-132314	Xenopus tropicalis	78.27	0.00e+00	958.00
IUUC-Xma-133939	Xiphophorus maculatus	68.03	0.00e+00	837.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence