iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044899

UUCD1 version

UUC-GoG-00272

Ensembl Protein ID

ENSGGOP00000006683.2

UniProt Accession

G3QVB9; G3QVB9_GORGO

Protein Name

Uncharacterized protein

Gene Name

KLHL21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000006829.2	ENSGGOT00000006856.2	ENSGGOP00000006683.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.70e-19	69.7	47	111
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.10e-09	34.9	147	175

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    Dvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           Dv+l+ + g+ f+ah++vLaa+S++F+a+f ++l+es+  ++v +++v p+ ++ ll+F+Ytg++ 
   Q: 47   DVTLEAAgGRDFPAHRAVLAAASPYFRAMFAGQLRESR-AERVRLHGVPPDMLQLLLDFSYTGRVA 111
           9*****99******************************.************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkh 30
            Ncl++ +fA++++c+ L++aa++fil+h
   Q: 147  ANCLDMQDFAEAFSCSGLASAAQRFILRH 175
           6***************************9 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

PRRPRQPSEG AMERPAPLAV LPFSDPAHAL SLLRGLSQLR AERKFLDVTL EAAGGRDFPA 60
HRAVLAAASP YFRAMFAGQL RESRAERVRL HGVPPDMLQL LLDFSYTGRV AVSGDNAEPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTCTCCGC AGGCCCCGGC CGCGGCGTCC TCGACAACCT AGCGAAGGCG CCATGGAGCG 60
ACCGGCGCCC CTGGCCGTGC TGCCCTTCTC GGACCCCGCG CACGCCCTAA GCCTGCTGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035853--P:chromosome passenger complex localization to spindle midzone
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001782	Ailuropoda melanoleuca	87.99	0.00e+00	910.00
IUUC-Apl-003189	Anas platyrhynchos	84.33	2.00e-141	494.00
IUUC-Ani-009467	Aspergillus nidulans	35.29	8.00e-08	51.20
IUUC-Ame-011774	Astyanax mexicanus	66.11	4.00e-137	480.00
IUUC-Bta-012367	Bos taurus	96.98	0.00e+00	1136.00
IUUC-Cja-019501	Callithrix jacchus	91.08	0.00e+00	1033.00
IUUC-Cfa-020550	Canis familiaris	96.98	0.00e+00	1135.00
IUUC-Cpo-022072	Cavia porcellus	97.25	0.00e+00	1110.00
IUUC-Csa-023364	Chlorocebus sabaeus	99.25	0.00e+00	1031.00
IUUC-Cin-025253	Ciona intestinalis	43.73	2.00e-148	519.00
IUUC-Csv-025871	Ciona savignyi	45.37	4.00e-154	538.00
IUUC-Dre-028694	Danio rerio	72.36	0.00e+00	858.00
IUUC-Dno-029082	Dasypus novemcinctus	93.76	0.00e+00	939.00
IUUC-Dor-030680	Dipodomys ordii	96.31	0.00e+00	1128.00
IUUC-Ete-032315	Echinops telfairi	96.33	0.00e+00	950.00
IUUC-Eca-033570	Equus caballus	96.43	0.00e+00	680.00
IUUC-Eeu-035067	Erinaceus europaeus	94.14	6.00e-141	494.00
IUUC-Fca-035663	Felis catus	91.49	6.00e-121	426.00
IUUC-Fal-037103	Ficedula albicollis	83.72	0.00e+00	898.00
IUUC-Gmo-039420	Gadus morhua	69.78	0.00e+00	842.00
IUUC-Ggr-039811	Gaeumannomyces graminis	38.36	3.00e-08	52.80
IUUC-Gga-040161	Gallus gallus	82.77	0.00e+00	864.00
IUUC-Gac-041755	Gasterosteus aculeatus	71.33	0.00e+00	862.00
IUUC-Hsa-045834	Homo sapiens	99.66	0.00e+00	1151.00
IUUC-Itr-048413	Ictidomys tridecemlineatus	96.82	0.00e+00	1133.00
IUUC-Lch-050338	Latimeria chalumnae	70.93	0.00e+00	872.00
IUUC-Loc-051780	Lepisosteus oculatus	74.87	0.00e+00	877.00
IUUC-Laf-053725	Loxodonta africana	94.00	0.00e+00	782.00
IUUC-Mcc-055032	Macaca mulatta	99.40	0.00e+00	985.00
IUUC-Meu-056661	Macropus eugenii	94.32	0.00e+00	769.00
IUUC-Mpo-057626	Magnaporthe poae	31.67	3.00e-07	49.70
IUUC-Mga-059821	Meleagris gallopavo	84.17	1.00e-125	441.00
IUUC-Mdo-062095	Monodelphis domestica	94.66	0.00e+00	957.00
IUUC-Mmu-063138	Mus musculus	96.65	0.00e+00	1137.00
IUUC-Mpu-066386	Mustela putorius furo	95.03	7.00e-180	622.00
IUUC-Mlu-067807	Myotis lucifugus	96.47	0.00e+00	687.00
IUUC-Nle-069181	Nomascus leucogenys	98.32	0.00e+00	1137.00
IUUC-Opr-070658	Ochotona princeps	96.65	0.00e+00	1155.00
IUUC-Ont-072209	Oreochromis niloticus	71.48	0.00e+00	850.00
IUUC-Oan-072861	Ornithorhynchus anatinus	90.23	3.00e-118	417.00
IUUC-Ocu-074631	Oryctolagus cuniculus	87.38	0.00e+00	981.00
IUUC-Ola-087553	Oryzias latipes	70.25	0.00e+00	837.00
IUUC-Oga-088782	Otolemur garnettii	96.82	0.00e+00	1140.00
IUUC-Oar-089634	Ovis aries	96.65	0.00e+00	1132.00
IUUC-Ptr-091259	Pan troglodytes	99.78	0.00e+00	862.00
IUUC-Pan-091734	Papio anubis	99.33	0.00e+00	1156.00
IUUC-Psi-092979	Pelodiscus sinensis	82.83	0.00e+00	920.00
IUUC-Pma-094459	Petromyzon marinus	52.86	3.00e-124	438.00
IUUC-Pfo-097446	Poecilia formosa	71.30	0.00e+00	849.00
IUUC-Pab-098765	Pongo abelii	99.33	0.00e+00	1154.00
IUUC-Pca-101018	Procavia capensis	99.42	4.00e-94	338.00
IUUC-Pva-102730	Pteropus vampyrus	93.97	0.00e+00	1090.00
IUUC-Rno-104972	Rattus norvegicus	97.25	0.00e+00	1133.00
IUUC-Ssc-115869	Sus scrofa	97.61	0.00e+00	976.00
IUUC-Tgu-116562	Taeniopygia guttata	83.57	0.00e+00	929.00
IUUC-Tru-118490	Takifugu rubripes	70.77	0.00e+00	844.00
IUUC-Tni-119898	Tetraodon nigroviridis	68.64	0.00e+00	811.00
IUUC-Ttr-128976	Tursiops truncatus	94.14	2.00e-140	492.00
IUUC-Xtr-132876	Xenopus tropicalis	73.33	0.00e+00	906.00
IUUC-Xma-133540	Xiphophorus maculatus	71.83	0.00e+00	852.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence