iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007794

Ensembl Protein ID

AAS51838

UniProt Accession

Q75AK9; Q75AK9_ASHGO

Genbank Protein ID

AAS51838.2

Protein Name

ADL082Cp

Genbank Nucleotide ID

AE016817

Gene Name

AGOS_ADL082C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_ADL082C	AAS51838	AAS51838

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	1.10e-07	29.9	136	180
E3 adaptor/Cullin RING/DCX/DWD	4.70e-50	163.4	375	413
UBD/Beta-Prp	9.30e-92	305.3	251	566

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 102  lldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
            ++ lpee+ ++il++ld ++l++aa vcrrwqela+++++w ++
   Q: 136  FISALPEEVALKILGYLDCQSLCSAAAVCRRWQELADDDTVWYHM 180
           6789*********************************99999765 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt++v+c+++ +   +  sGsdD ti++WD+rt+++++
   Q: 375  GHTGWVNCVKLhPKsFTCFSGSDDMTIRMWDIRTNTCVR 413
           8**********954456899***************9986 PP

UBD/Beta-Prp

   S: 2    iktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           i+++kgh+++v++ ++    ++ll+tgs+d+t+ +wd+ tgkl+r+lsgh+++v+a++f+++   l+tgs D+ti+vw++ tg cv+t++gh+dsvls+++
   Q: 251  IQEFKGHMDGVLS-LQL--TNKLLLTGSYDSTVAIWDLATGKLIRRLSGHTDGVKALRFDDQ--KLITGSLDKTIRVWNYVTGACVSTYRGHQDSVLSVDS 346
           7899*********.888..9******************************************..6************************************ PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls................ 187
           ++  + +vsGs+d+t++vw++e+++c+  tl+gh+g+vncv++hp+++ ++sGs+D t+r+Wd++t++++r + g h ++v++++                
   Q: 347  FR--KLIVSGSADKTVKVWHVESRTCY--TLRGHTGWVNCVKLHPKSFTCFSGSDDMTIRMWDIRTNTCVRVFHG-HVGQVQKVIpltlgsdliedpkdav 442
           **..***********************..7********************************************9.*********9998888776666666 PP
   S: 188  ........fdsng................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
                                        ++l+s+sld+t+klw+++tg c+rt+ gh + v++++++  + r+vsgs+D+s ++Wdl++g++++t+ + +
   Q: 443  vppdatapA---HdpsvqaanfdhslpypTHLLSCSLDNTIKLWNVKTGACIRTQFGHVEGVWDIAAD--NFRIVSGSHDRSCKVWDLQTGKCMHTFVGIH 538
           555555550...05556666666667******************************************..*****************************99 PP
   S: 265  ssvisvavlsfgdnvlvlgsedskvniwklk 295
               +va++++gd+++v+g+e ++v++++++
   Q: 539  ---APVACVGIGDSEFVSGDELGCVKLYNFD 566
           ...89999999*****************996 PP

Organism

Ashbya gossypii

Protein Sequence
(Fasta)

MSNSTAGHLQ QDGGHMSNKR EAAEVDAEMQ PATKQLRAPQ YNFVRYCYRH NPDIQAAPTQ 60
VRCVRQEQQR REEWQARVGE LSSEGERQVV QEAVRLFDSS NDKLRKLMLE GMLLKSCFPQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTAACA GCACAGCGGG CCACCTTCAA CAGGATGGCG GACACATGAG CAATAAGCGC 60
GAGGCGGCAG AGGTGGATGC AGAGATGCAG CCGGCGACAA AGCAGCTACG GGCGCCGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0043224--C:nuclear SCF ubiquitin ligase complex
GO:0071276--P:cellular response to cadmium ion
GO:0006270--P:DNA replication initiation
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030174--P:regulation of DNA-dependent DNA replication initiation
GO:0000083--P:regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0046685--P:response to arsenic-containing substance
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

ago:AGOS_ADL082C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002406	Ailuropoda melanoleuca	31.48	3.00e-65	240.00
IUUC-Apl-003489	Anas platyrhynchos	31.48	5.00e-65	240.00
IUUC-Aca-005318	Anolis carolinensis	31.69	2.00e-65	240.00
IUUC-Acl-008078	Aspergillus clavatus	43.14	4.00e-143	499.00
IUUC-Afl-008744	Aspergillus flavus	40.64	5.00e-121	426.00
IUUC-Afu-008939	Aspergillus fumigatus	43.00	7.00e-136	475.00
IUUC-Ani-009383	Aspergillus nidulans	43.56	9.00e-137	478.00
IUUC-Ang-009570	Aspergillus niger	43.06	2.00e-134	470.00
IUUC-Aor-010217	Aspergillus oryzae	40.64	5.00e-121	426.00
IUUC-Ate-010336	Aspergillus terreus	45.07	2.00e-98	350.00
IUUC-Ame-010898	Astyanax mexicanus	31.69	2.00e-65	241.00
IUUC-Bgr-012225	Blumeria graminis	38.71	3.00e-128	449.00
IUUC-Bta-012391	Bos taurus	31.48	1.00e-64	239.00
IUUC-Bci-013916	Botrytis cinerea	42.03	2.00e-134	470.00
IUUC-Cel-018392	Caenorhabditis elegans	26.30	1.00e-37	149.00
IUUC-Cja-018902	Callithrix jacchus	31.48	4.00e-65	240.00
IUUC-Cfa-020237	Canis familiaris	31.48	4.00e-65	240.00
IUUC-Cpo-022234	Cavia porcellus	31.48	8.00e-65	239.00
IUUC-Cre-022837	Chlamydomonas reinhardtii	33.76	2.00e-36	144.00
IUUC-Csa-023532	Chlorocebus sabaeus	31.48	4.00e-65	240.00
IUUC-Cin-025188	Ciona intestinalis	29.72	9.00e-49	186.00
IUUC-Cgl-026550	Colletotrichum gloeosporioides	40.34	5.00e-120	422.00
IUUC-Cne-026800	Cryptococcus neoformans	41.15	8.00e-49	186.00
IUUC-Dre-028303	Danio rerio	31.89	3.00e-66	244.00
IUUC-Dno-029576	Dasypus novemcinctus	29.84	4.00e-60	224.00
IUUC-Dor-030196	Dipodomys ordii	31.28	2.00e-63	234.00
IUUC-Dse-031413	Dothistroma septosporum	37.17	4.00e-109	386.00
IUUC-Ete-032791	Echinops telfairi	31.70	7.00e-64	236.00
IUUC-Eca-033424	Equus caballus	31.48	1.00e-64	238.00
IUUC-Eeu-034996	Erinaceus europaeus	31.40	3.00e-65	240.00
IUUC-Fca-036422	Felis catus	31.48	3.00e-65	240.00
IUUC-Fal-037267	Ficedula albicollis	31.69	3.00e-64	237.00
IUUC-Fox-037683	Fusarium oxysporum	42.86	8.00e-121	425.00
IUUC-Fso-038092	Fusarium solani	41.40	3.00e-134	469.00
IUUC-Gmo-039119	Gadus morhua	28.31	3.00e-49	187.00
IUUC-Ggr-039842	Gaeumannomyces graminis	36.33	1.00e-115	408.00
IUUC-Gga-040667	Gallus gallus	31.48	5.00e-65	239.00
IUUC-Ggo-044422	Gorilla gorilla	31.48	6.00e-65	239.00
IUUC-Hsa-045898	Homo sapiens	31.48	6.00e-65	239.00
IUUC-Itr-048241	Ictidomys tridecemlineatus	31.70	1.00e-63	234.00
IUUC-Kpa-049101	Komagataella pastoris	54.96	3.00e-180	622.00
IUUC-Lch-050414	Latimeria chalumnae	31.28	1.00e-64	238.00
IUUC-Loc-052348	Lepisosteus oculatus	31.89	1.00e-65	242.00
IUUC-Lma-053200	Leptosphaeria maculans	40.16	1.00e-133	468.00
IUUC-Laf-054054	Loxodonta africana	31.69	1.00e-65	241.00
IUUC-Mcc-055056	Macaca mulatta	31.48	4.00e-65	240.00
IUUC-Meu-056078	Macropus eugenii	30.70	5.00e-40	156.00
IUUC-Mor-057039	Magnaporthe oryzae	38.81	2.00e-119	420.00
IUUC-Mpo-057381	Magnaporthe poae	39.22	2.00e-124	437.00
IUUC-Mla-059099	Melampsora laricipopulina	36.63	3.00e-99	353.00
IUUC-Mga-059255	Meleagris gallopavo	31.48	7.00e-65	239.00
IUUC-Mvi-060426	Microbotryum violaceum	41.42	7.00e-51	193.00
IUUC-Mmr-061292	Microcebus murinus	31.48	4.00e-65	240.00
IUUC-Mdo-062304	Monodelphis domestica	31.48	6.00e-65	240.00
IUUC-Mmu-063610	Mus musculus	31.48	2.00e-65	241.00
IUUC-Mpu-065931	Mustela putorius furo	31.48	4.00e-65	240.00
IUUC-Mlu-066976	Myotis lucifugus	31.48	3.00e-65	241.00
IUUC-Nfi-068464	Neosartorya fischeri	43.17	3.00e-135	473.00
IUUC-Ncr-068962	Neurospora crassa	42.38	4.00e-100	356.00
IUUC-Nle-070174	Nomascus leucogenys	31.48	6.00e-65	239.00
IUUC-Opr-071229	Ochotona princeps	28.60	3.00e-51	193.00
IUUC-Ont-071997	Oreochromis niloticus	30.73	5.00e-64	236.00
IUUC-Oan-072936	Ornithorhynchus anatinus	31.48	4.00e-65	240.00
IUUC-Ocu-074742	Oryctolagus cuniculus	31.48	4.00e-65	240.00
IUUC-Ola-087098	Oryzias latipes	30.92	3.00e-63	233.00
IUUC-Oga-088604	Otolemur garnettii	29.04	5.00e-51	193.00
IUUC-Oar-090220	Ovis aries	31.43	1.00e-64	239.00
IUUC-Ptr-090492	Pan troglodytes	31.48	6.00e-65	239.00
IUUC-Pan-091770	Papio anubis	31.48	4.00e-65	240.00
IUUC-Psi-093207	Pelodiscus sinensis	31.48	9.00e-65	239.00
IUUC-Pma-094749	Petromyzon marinus	30.17	3.00e-62	230.00
IUUC-Pno-095133	Phaeosphaeria nodorum	42.42	3.00e-86	310.00
IUUC-Pfo-096493	Poecilia formosa	31.28	3.00e-64	236.00
IUUC-Pab-098141	Pongo abelii	31.48	1.00e-64	238.00
IUUC-Pca-100571	Procavia capensis	34.91	5.00e-52	196.00
IUUC-Pva-102988	Pteropus vampyrus	31.48	3.00e-65	240.00
IUUC-Pgr-103527	Puccinia graminis	35.13	5.00e-57	213.00
IUUC-Ptt-103819	Puccinia triticina	32.74	4.00e-52	196.00
IUUC-Pte-104035	Pyrenophora teres	40.59	4.00e-123	432.00
IUUC-Pyt-104799	Pyrenophora triticirepentis	40.89	6.00e-124	435.00
IUUC-Rno-105706	Rattus norvegicus	31.69	1.00e-65	241.00
IUUC-Sce-106343	Saccharomyces cerevisiae	64.59	0.00e+00	771.00
IUUC-Sha-107653	Sarcophilus harrisii	31.48	6.00e-65	239.00
IUUC-Sja-107945	Schizosaccharomyces japonicus	43.59	8.00e-110	388.00
IUUC-Spo-108115	Schizosaccharomyces pombe	41.28	2.00e-107	380.00
IUUC-Sar-113600	Sorex araneus	32.27	3.00e-54	204.00
IUUC-Sre-115173	Sporisorium reilianum	36.31	9.00e-52	196.00
IUUC-Ssc-115787	Sus scrofa	31.29	3.00e-63	234.00
IUUC-Tgu-117510	Taeniopygia guttata	31.48	6.00e-65	239.00
IUUC-Tru-117819	Takifugu rubripes	30.92	2.00e-65	241.00
IUUC-Tsy-118828	Tarsius syrichta	31.48	3.00e-65	240.00
IUUC-Tni-120468	Tetraodon nigroviridis	31.11	2.00e-65	241.00
IUUC-Tre-122126	Trichoderma reesei	40.17	3.00e-132	463.00
IUUC-Tvi-122482	Trichoderma virens	41.95	9.00e-136	474.00
IUUC-Tme-127212	Tuber melanosporum	46.85	6.00e-146	508.00
IUUC-Tbe-127925	Tupaia belangeri	31.48	7.00e-65	239.00
IUUC-Ttr-128899	Tursiops truncatus	31.48	3.00e-65	241.00
IUUC-Uma-129406	Ustilago maydis	40.34	4.00e-51	194.00
IUUC-Vda-129799	Verticillium dahliae	39.90	5.00e-131	459.00
IUUC-Vpa-130082	Vicugna pacos	32.22	1.00e-62	231.00
IUUC-Xtr-132213	Xenopus tropicalis	31.07	5.00e-64	236.00
IUUC-Xma-133646	Xiphophorus maculatus	31.21	6.00e-64	236.00
IUUC-Yli-134408	Yarrowia lipolytica	44.95	4.00e-150	523.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence