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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Spo-108115
UUCD1 version UUC-ScP-00038
Ensembl Protein ID SPAC57A10.05c.1:pep
UniProt Accession P87053; POF1_SCHPO
Genbank Protein ID BAA84528.1; CAB08168.1
Protein Name F-box/WD repeat-containing protein pof1; Skp1-binding protein 1
Genbank Nucleotide ID AB032410; CU329670
Gene Name pof1; sbp1; SPAC57A10.05c
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPAC57A10.05c SPAC57A10.05c.1 SPAC57A10.05c.1:pep
Annotation
mRNA Expression
GEO
Protein-protein Interaction
Mentha
Post-translational Modifications (PTMs)
dbPAFdbPTMUniProt
Protein Expression/Proteomics
Status Reviewed
Details
Family Domain References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box F-box 15660136
E3 adaptor/Cullin RING/DCX/DWD WD_repeat 15660136
Classification
Family E-value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 8.80e-55 178.4 311 346
E3 adaptor/Cullin RING/SCF/F-box 2.50e-06 25.7 110 153
UBD/Beta-Prp 9.30e-74 246.3 268 541
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvll 36
           gH+++vtcl+f d + l+sGs D+ti++W++rt  ++
   Q: 311  GHSSGVTCLQF-DqCKLISGSMDKTIRIWNYRTSECI 346
           8**********.669*****************99886 PP
   

   E3 adaptor/Cullin RING/SCF/F-box
   S: 103  ldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
           l+ lp ei ++il++ld+++l++aa+v+++w+ela+++ +w+++
   Q: 110  LSLLPVEISFRILSFLDARSLCQAAQVSKHWKELADDDVIWHRM 153
           6779*************************************987 PP
   

   UBD/Beta-Prp
   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           +l+gh ++v++ ++    +++la+gs+d+ti++w++ t + ++ l+gh+++vt+++f++    l++gs D+ti++w+++t++c+++l+gh
   Q: 268  VLSGHSDGVMC-LQL--VRNILASGSYDATIRLWNLATFQQVALLEGHSSGVTCLQFDQC--KLISGSMDKTIRIWNYRTSECISILHGH 352
           57888898888.777..7******************************************..6*************************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           +dsvl+l+f+     lvsGs+d t+++w+ + g+ +  tl+gh+g vn+v++  d  l+ sGs+D+t+++W+l+t+++l+t++  h ++v
   Q: 353  TDSVLCLTFDS--TLLVSGSADCTVKLWHFSGGKRI--TLRGHTGPVNSVRIIRDRGLVLSGSDDSTIKIWSLETNTCLHTFSA-HIGPV 437
           ***********..***********************..7*******************************************98.***** PP
   S: 184  yslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavl 273
           +sl++ +   +l s+sldgt+k wd+++++cv+tl gh + v+ ++++  + rl+sg++Dg++++W  +  ++++tl++h + v+sva+ 
   Q: 438  QSLALAD--SRLFSCSLDGTIKQWDIEKKKCVHTLFGHIEGVWEIAAD--HLRLISGAHDGVVKVW--EACECVHTLKNHSEPVTSVAL- 520
           *******..68************************************9..****************..7********************. PP
   S: 274  sfgdnvlvlgsedskvniwklkk 296
             gd ++v+gsed+k+ +w +++
   Q: 521  --GDCEVVSGSEDGKIYLWLFNN 541
           ..*****************9965 PP
   
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Required for the inactivation of zip1 via ubiquitination.
 Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Required for the inactivation of zip1 via ubiquitination.
Protein Sequence
(Fasta)
MTTGYESVPT SEPSDNLAPR AELWQRHLLE KKEGDQSISV SAFNISSMHN ELSGLSEKSR 60
QRVEAVWAAF SEASCSERKL ALQGILNNCS SSLLSFASST LDSLVRLDFL SLLPVEISFR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108115|E3,F-box;E3,WD_repeat;UBD,Beta-Prp|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCGCTATTTC CTTCTTCAAT ATTGTTCATG TTATGTGATT AACCGAAAAT CATGTATTCT 60
TTCTTCTTGT AATAAATCAT CGATTTAGCT TTGTTTACGA CAACTATATA TAGGTGAACA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108115|E3,F-box;E3,WD_repeat;UBD,Beta-Prp|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR002469--Peptidase_S9B_N
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12937--F-box-like
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0030674--F:protein binding, bridging
GO:0071276--P:cellular response to cadmium ion
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG spo:SPAC57A10.05c
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002406 Ailuropoda melanoleuca 32.14 2.00e-63 235.00
IUUC-Apl-003489 Anas platyrhynchos 32.35 9.00e-64 236.00
IUUC-Aca-005318 Anolis carolinensis 32.35 2.00e-63 234.00
IUUC-Ago-007794 Ashbya gossypii 41.28 1.00e-104 371.00
IUUC-Acl-008078 Aspergillus clavatus 38.90 3.00e-112 397.00
IUUC-Afl-008744 Aspergillus flavus 40.89 1.00e-116 411.00
IUUC-Afu-008939 Aspergillus fumigatus 37.36 4.00e-108 383.00
IUUC-Ani-009383 Aspergillus nidulans 40.17 1.00e-126 444.00
IUUC-Ang-009570 Aspergillus niger 39.24 5.00e-106 376.00
IUUC-Aor-010217 Aspergillus oryzae 40.89 1.00e-116 411.00
IUUC-Ate-010336 Aspergillus terreus 40.39 1.00e-120 424.00
IUUC-Ame-010898 Astyanax mexicanus 31.87 1.00e-62 232.00
IUUC-Bgr-012225 Blumeria graminis 38.22 7.00e-113 399.00
IUUC-Bta-012391 Bos taurus 32.14 1.00e-62 232.00
IUUC-Bci-013916 Botrytis cinerea 45.56 1.00e-99 355.00
IUUC-Cja-018902 Callithrix jacchus 32.14 2.00e-63 234.00
IUUC-Cfa-020237 Canis familiaris 32.14 2.00e-63 234.00
IUUC-Cpo-022234 Cavia porcellus 32.14 7.00e-63 233.00
IUUC-Cre-022837 Chlamydomonas reinhardtii 38.71 1.00e-45 175.00
IUUC-Csa-023532 Chlorocebus sabaeus 32.14 2.00e-63 234.00
IUUC-Cgl-026550 Colletotrichum gloeosporioides 36.53 3.00e-105 374.00
IUUC-Cne-026800 Cryptococcus neoformans 37.80 4.00e-85 307.00
IUUC-Cme-027168 Cyanidioschyzon merolae 30.28 4.00e-25 107.00
IUUC-Dre-028303 Danio rerio 32.08 3.00e-63 234.00
IUUC-Dno-029576 Dasypus novemcinctus 30.88 8.00e-59 219.00
IUUC-Dor-030196 Dipodomys ordii 32.14 3.00e-62 231.00
IUUC-Dse-031413 Dothistroma septosporum 40.05 5.00e-84 303.00
IUUC-Ete-032791 Echinops telfairi 31.99 3.00e-62 231.00
IUUC-Eca-033424 Equus caballus 32.14 1.00e-62 232.00
IUUC-Eeu-034996 Erinaceus europaeus 31.51 4.00e-61 227.00
IUUC-Fca-036422 Felis catus 32.14 2.00e-63 235.00
IUUC-Fal-037267 Ficedula albicollis 32.35 7.00e-64 236.00
IUUC-Fox-037683 Fusarium oxysporum 39.64 3.00e-107 380.00
IUUC-Fso-038092 Fusarium solani 39.39 9.00e-115 405.00
IUUC-Ggr-039842 Gaeumannomyces graminis 36.21 2.00e-96 344.00
IUUC-Gga-040667 Gallus gallus 32.35 7.00e-64 236.00
IUUC-Ggo-044422 Gorilla gorilla 32.14 2.00e-63 234.00
IUUC-Hsa-045898 Homo sapiens 32.14 2.00e-63 235.00
IUUC-Itr-048241 Ictidomys tridecemlineatus 31.72 1.00e-62 232.00
IUUC-Kpa-049101 Komagataella pastoris 41.37 3.00e-113 400.00
IUUC-Lch-050414 Latimeria chalumnae 32.14 1.00e-63 236.00
IUUC-Loc-052348 Lepisosteus oculatus 32.29 2.00e-63 234.00
IUUC-Lma-053200 Leptosphaeria maculans 40.23 6.00e-94 336.00
IUUC-Laf-054054 Loxodonta africana 32.35 6.00e-64 236.00
IUUC-Mcc-055056 Macaca mulatta 32.14 2.00e-63 234.00
IUUC-Mor-057039 Magnaporthe oryzae 35.04 2.00e-89 321.00
IUUC-Mpo-057381 Magnaporthe poae 39.44 8.00e-115 405.00
IUUC-Mla-059099 Melampsora laricipopulina 38.20 6.00e-95 340.00
IUUC-Mga-059255 Meleagris gallopavo 32.35 9.00e-64 236.00
IUUC-Mvi-060426 Microbotryum violaceum 41.49 3.00e-53 201.00
IUUC-Mmr-061292 Microcebus murinus 32.14 2.00e-63 235.00
IUUC-Mdo-062304 Monodelphis domestica 31.72 1.00e-63 236.00
IUUC-Mmu-063610 Mus musculus 31.72 6.00e-64 236.00
IUUC-Mpu-065931 Mustela putorius furo 32.14 2.00e-63 235.00
IUUC-Mlu-066976 Myotis lucifugus 32.14 1.00e-63 235.00
IUUC-Nfi-068464 Neosartorya fischeri 39.49 2.00e-106 377.00
IUUC-Ncr-068962 Neurospora crassa 41.11 7.00e-91 326.00
IUUC-Nle-070174 Nomascus leucogenys 32.14 2.00e-63 235.00
IUUC-Ont-071997 Oreochromis niloticus 31.66 5.00e-63 233.00
IUUC-Oan-072936 Ornithorhynchus anatinus 32.14 3.00e-63 234.00
IUUC-Ocu-074742 Oryctolagus cuniculus 32.14 2.00e-63 234.00
IUUC-Ola-086653 Oryzias latipes 32.35 3.00e-62 230.00
IUUC-Olu-087837 Ostreococcus lucimarinus 36.36 2.00e-38 150.00
IUUC-Oar-090220 Ovis aries 31.88 6.00e-62 229.00
IUUC-Ptr-090492 Pan troglodytes 32.14 2.00e-63 235.00
IUUC-Pan-091770 Papio anubis 32.14 2.00e-63 234.00
IUUC-Psi-093207 Pelodiscus sinensis 32.14 6.00e-63 233.00
IUUC-Pma-094749 Petromyzon marinus 31.66 5.00e-62 229.00
IUUC-Pno-095133 Phaeosphaeria nodorum 41.55 7.00e-81 292.00
IUUC-Pfo-096493 Poecilia formosa 32.08 7.00e-61 226.00
IUUC-Pab-098141 Pongo abelii 32.14 1.00e-62 232.00
IUUC-Pca-100571 Procavia capensis 32.35 2.00e-48 184.00
IUUC-Pva-102988 Pteropus vampyrus 32.14 2.00e-63 234.00
IUUC-Pgr-103527 Puccinia graminis 39.56 5.00e-61 226.00
IUUC-Pte-104035 Pyrenophora teres 40.56 4.00e-88 317.00
IUUC-Pyt-104799 Pyrenophora triticirepentis 38.48 6.00e-88 316.00
IUUC-Rno-105706 Rattus norvegicus 31.93 3.00e-64 237.00
IUUC-Sce-106343 Saccharomyces cerevisiae 38.24 4.00e-104 370.00
IUUC-Sha-107653 Sarcophilus harrisii 31.72 1.00e-63 235.00
IUUC-Sja-107945 Schizosaccharomyces japonicus 62.11 0.00e+00 662.00
IUUC-Sar-113600 Sorex araneus 32.92 2.00e-55 208.00
IUUC-Sre-115173 Sporisorium reilianum 44.17 1.00e-55 209.00
IUUC-Ssc-115787 Sus scrofa 31.37 1.00e-59 222.00
IUUC-Tgu-117510 Taeniopygia guttata 32.35 9.00e-64 236.00
IUUC-Tru-117819 Takifugu rubripes 32.08 4.00e-64 237.00
IUUC-Tsy-118828 Tarsius syrichta 32.14 2.00e-63 234.00
IUUC-Tni-120468 Tetraodon nigroviridis 32.08 5.00e-64 236.00
IUUC-Tre-122126 Trichoderma reesei 39.46 6.00e-116 409.00
IUUC-Tvi-122482 Trichoderma virens 39.96 7.00e-119 419.00
IUUC-Tme-127212 Tuber melanosporum 39.63 2.00e-108 384.00
IUUC-Tbe-127925 Tupaia belangeri 32.14 4.00e-63 233.00
IUUC-Ttr-128899 Tursiops truncatus 32.14 2.00e-63 235.00
IUUC-Uma-129406 Ustilago maydis 42.92 2.00e-54 205.00
IUUC-Vda-129799 Verticillium dahliae 42.25 2.00e-88 317.00
IUUC-Vpa-130082 Vicugna pacos 32.36 9.00e-60 222.00
IUUC-Xtr-132213 Xenopus tropicalis 32.14 1.00e-63 236.00
IUUC-Xma-132996 Xiphophorus maculatus 33.69 1.00e-63 234.00
IUUC-Yli-134408 Yarrowia lipolytica 37.29 2.00e-100 358.00
Created Date 25-Jun-2017

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