iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062363

UUCD1 version

UUC-MoD-00878

Ensembl Protein ID

ENSMODP00000025466.3

UniProt Accession

F7FK00; F7FK00_MONDO

Protein Name

Uncharacterized protein

Gene Name

SKP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000020361.3	ENSMODT00000025917.3	ENSMODP00000025466.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	1.20e-06	28.8	83	136

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 92   ptpeegpdaglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
            + e+g+   ++d lp+e+l++i+++l+ ++l+ra+ +c+rw++l+ +++lw+t+
   Q: 83   QSRENGS-GISWDMLPDELLLSIFSYLSLPDLVRASGICKRWHRLSFDESLWQTL 136
           4455555.456789*****************************99999****997 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MPRKHLQEIP DLSRNVNITF TWGWDLNKTS DLLSGMGVAV LEKEKVDSEN IPQELLLTQG 60
PAPKKQKVKA KEKDFVIARR PRQSRENGSG ISWDMLPDEL LLSIFSYLSL PDLVRASGIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCGCAGCGG CCACGTCCGG GCCAGCGCCC CGGGGGAGGC AGCGAAGCTC CCGGGGCCAA 60
GGCGCCCCCG TCAGCCGCTG CCTCCGACTC ACCGGAGAGA CTGTTCCCCT CAGCAGGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051726--P:regulation of cell cycle
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mdo:100020421

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002197	Ailuropoda melanoleuca	69.81	3.00e-162	564.00
IUUC-Apl-003453	Anas platyrhynchos	67.86	6.00e-123	433.00
IUUC-Aca-005185	Anolis carolinensis	60.99	2.00e-138	485.00
IUUC-Ago-007783	Ashbya gossypii	42.55	6.00e-05	42.70
IUUC-Ame-010665	Astyanax mexicanus	50.24	6.00e-99	354.00
IUUC-Bta-013450	Bos taurus	68.16	4.00e-167	580.00
IUUC-Cel-018410	Caenorhabditis elegans	25.85	4.00e-24	105.00
IUUC-Cja-019834	Callithrix jacchus	69.34	1.00e-169	588.00
IUUC-Cfa-020401	Canis familiaris	69.81	1.00e-168	585.00
IUUC-Cpo-022183	Cavia porcellus	70.38	4.00e-169	587.00
IUUC-Csa-023418	Chlorocebus sabaeus	70.28	7.00e-170	589.00
IUUC-Cho-024412	Choloepus hoffmanni	67.98	1.00e-132	466.00
IUUC-Cin-025248	Ciona intestinalis	31.00	4.00e-40	159.00
IUUC-Csv-026189	Ciona savignyi	33.33	7.00e-35	141.00
IUUC-Cme-027297	Cyanidioschyzon merolae	46.34	5.00e-07	48.90
IUUC-Dre-028032	Danio rerio	52.53	7.00e-112	397.00
IUUC-Dno-029222	Dasypus novemcinctus	70.52	4.00e-172	597.00
IUUC-Dor-030505	Dipodomys ordii	66.67	3.00e-126	444.00
IUUC-Dme-031972	Drosophila melanogaster	35.47	2.00e-50	193.00
IUUC-Ete-032234	Echinops telfairi	66.29	2.00e-84	306.00
IUUC-Eca-033944	Equus caballus	70.28	1.00e-170	592.00
IUUC-Eeu-035008	Erinaceus europaeus	62.71	1.00e-96	346.00
IUUC-Fca-035412	Felis catus	70.05	5.00e-169	587.00
IUUC-Fal-037337	Ficedula albicollis	64.92	3.00e-138	484.00
IUUC-Gmo-038934	Gadus morhua	47.26	2.00e-42	166.00
IUUC-Gga-041152	Gallus gallus	68.35	1.00e-159	556.00
IUUC-Gac-041819	Gasterosteus aculeatus	47.69	6.00e-78	284.00
IUUC-Ggo-045479	Gorilla gorilla	68.64	2.00e-137	482.00
IUUC-Hsa-046512	Homo sapiens	69.58	2.00e-168	585.00
IUUC-Itr-048515	Ictidomys tridecemlineatus	70.44	3.00e-162	564.00
IUUC-Lch-050115	Latimeria chalumnae	59.76	3.00e-141	494.00
IUUC-Loc-052554	Lepisosteus oculatus	52.73	8.00e-115	406.00
IUUC-Laf-053563	Loxodonta africana	69.60	1.00e-165	576.00
IUUC-Mcc-055143	Macaca mulatta	70.62	4.00e-170	590.00
IUUC-Meu-056593	Macropus eugenii	74.00	3.00e-129	454.00
IUUC-Mga-060084	Meleagris gallopavo	63.98	9.00e-94	336.00
IUUC-Mmr-060660	Microcebus murinus	70.99	3.00e-173	600.00
IUUC-Mmu-063287	Mus musculus	65.57	2.00e-158	551.00
IUUC-Mpu-065791	Mustela putorius furo	69.81	5.00e-169	587.00
IUUC-Mlu-067714	Myotis lucifugus	68.94	2.00e-160	558.00
IUUC-Nle-069823	Nomascus leucogenys	70.05	1.00e-169	589.00
IUUC-Opr-071046	Ochotona princeps	56.64	2.00e-70	259.00
IUUC-Ont-071820	Oreochromis niloticus	46.84	9.00e-66	243.00
IUUC-Ocu-074868	Oryctolagus cuniculus	70.28	9.00e-171	592.00
IUUC-Obr-076082	Oryza brachyantha	57.14	8.00e-05	41.60
IUUC-Opu-083705	Oryza punctata	43.75	1.00e-04	42.00
IUUC-Oru-084450	Oryza rufipogon	41.03	5.00e-05	43.50
IUUC-Ola-086608	Oryzias latipes	49.74	2.00e-81	296.00
IUUC-Oga-089044	Otolemur garnettii	70.75	3.00e-173	601.00
IUUC-Oar-089650	Ovis aries	68.63	1.00e-167	582.00
IUUC-Ptr-090743	Pan troglodytes	69.58	1.00e-168	585.00
IUUC-Pan-092501	Papio anubis	70.52	8.00e-171	593.00
IUUC-Psi-094032	Pelodiscus sinensis	66.98	4.00e-161	560.00
IUUC-Pfo-097279	Poecilia formosa	45.99	5.00e-63	234.00
IUUC-Pab-097821	Pongo abelii	69.49	1.00e-138	486.00
IUUC-Pca-100100	Procavia capensis	68.36	5.00e-133	467.00
IUUC-Pva-103181	Pteropus vampyrus	69.49	5.00e-132	464.00
IUUC-Rno-105091	Rattus norvegicus	65.80	2.00e-159	555.00
IUUC-Sha-107226	Sarcophilus harrisii	89.10	0.00e+00	717.00
IUUC-Smo-109321	Selaginella moellendorffii	25.30	2.00e-11	64.70
IUUC-Sly-110947	Solanum lycopersicum	31.58	5.00e-06	45.10
IUUC-Ssc-115665	Sus scrofa	70.05	2.00e-170	591.00
IUUC-Tgu-116982	Taeniopygia guttata	60.90	1.00e-131	462.00
IUUC-Tru-118276	Takifugu rubripes	45.65	2.00e-74	272.00
IUUC-Tsy-119074	Tarsius syrichta	71.19	5.00e-144	503.00
IUUC-Tni-120702	Tetraodon nigroviridis	47.84	2.00e-48	186.00
IUUC-Tbe-127990	Tupaia belangeri	69.13	3.00e-115	408.00
IUUC-Ttr-128661	Tursiops truncatus	60.77	6.00e-85	307.00
IUUC-Uma-129466	Ustilago maydis	27.03	5.00e-06	46.60
IUUC-Xtr-132166	Xenopus tropicalis	60.14	2.00e-129	455.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence