iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027836

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ring finger protein 121

Genbank Nucleotide ID

CU694956

Gene Name

rnf121

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000060282.5	ENSDART00000084780.5	ENSDARP00000079215.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.80e-06	29.3	230	280

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..........kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C +            ++ ++ l C+Hvfh+ C+  w    +   k+++CP+C+
   Q: 230  CAVCGQTTlvdanqegiiEN-TYRLTCNHVFHEFCIRGW----CIVGKKQTCPYCK 280
           99995544455555555455.77799*************....889999******7 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MAGVFEVEVD GVEHDHGHGH HEDGKIDLSR LSPEEKWRLD HAKLHAKHKG HEAMHAEMVL 60
ILIVTLVVAQ LALVQWKQRH QKSYNMVTLF QMWVIPLYFT SKLHWWRFMV VWFTFSIITA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCAACAGC TCCACTCCAG CACAGCAGCC GGCGGTGTGC GCTAGTGCAG CAGAAGAAAA 60
AGGAAGCATA ACCCGGAAGC GTTGTGTCCA GTCTGCTGCA ACGACTGCAT CGGCTGTTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0019228--P:neuronal action potential
GO:0072659--P:protein localization to plasma membrane
GO:1903069--P:regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0001966--P:thigmotaxis

KEGG

dre:606559

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002350	Ailuropoda melanoleuca	81.76	2.00e-149	521.00
IUUC-Apl-003882	Anas platyrhynchos	74.32	9.00e-124	436.00
IUUC-Aca-004343	Anolis carolinensis	71.74	4.00e-19	85.50
IUUC-Ame-010680	Astyanax mexicanus	84.94	2.00e-158	551.00
IUUC-Bta-013045	Bos taurus	83.33	5.00e-144	503.00
IUUC-Cel-018296	Caenorhabditis elegans	51.91	3.00e-99	355.00
IUUC-Cja-019866	Callithrix jacchus	81.76	1.00e-149	522.00
IUUC-Cfa-021176	Canis familiaris	82.14	5.00e-149	520.00
IUUC-Cpo-022268	Cavia porcellus	81.76	3.00e-148	518.00
IUUC-Csa-023727	Chlorocebus sabaeus	82.41	5.00e-150	523.00
IUUC-Cho-025016	Choloepus hoffmanni	82.74	2.00e-150	525.00
IUUC-Cin-025281	Ciona intestinalis	63.91	9.00e-124	436.00
IUUC-Csv-026338	Ciona savignyi	63.29	4.00e-112	397.00
IUUC-Dno-029737	Dasypus novemcinctus	80.71	1.00e-147	515.00
IUUC-Dor-031070	Dipodomys ordii	75.41	8.00e-132	462.00
IUUC-Dme-031867	Drosophila melanogaster	59.67	3.00e-111	395.00
IUUC-Ete-032964	Echinops telfairi	75.24	1.00e-140	492.00
IUUC-Eca-034398	Equus caballus	82.08	1.00e-149	522.00
IUUC-Fca-035807	Felis catus	82.14	1.00e-148	519.00
IUUC-Fal-036721	Ficedula albicollis	83.68	5.00e-140	489.00
IUUC-Gmo-039699	Gadus morhua	84.69	9.00e-145	506.00
IUUC-Gga-040840	Gallus gallus	82.25	1.00e-140	491.00
IUUC-Gac-042639	Gasterosteus aculeatus	82.23	4.00e-146	510.00
IUUC-Ggo-045576	Gorilla gorilla	82.62	3.00e-149	521.00
IUUC-Hsa-046468	Homo sapiens	82.08	8.00e-150	523.00
IUUC-Itr-048638	Ictidomys tridecemlineatus	83.33	2.00e-127	447.00
IUUC-Lch-050207	Latimeria chalumnae	76.22	2.00e-130	458.00
IUUC-Loc-052172	Lepisosteus oculatus	83.06	9.00e-151	526.00
IUUC-Laf-053879	Loxodonta africana	81.76	3.00e-149	521.00
IUUC-Mcc-055492	Macaca mulatta	82.41	5.00e-150	523.00
IUUC-Meu-055976	Macropus eugenii	71.24	1.00e-120	425.00
IUUC-Mga-059989	Meleagris gallopavo	81.82	4.00e-147	514.00
IUUC-Mmr-060894	Microcebus murinus	82.41	5.00e-150	523.00
IUUC-Mdo-061826	Monodelphis domestica	81.97	6.00e-145	506.00
IUUC-Mmu-063717	Mus musculus	82.41	6.00e-150	523.00
IUUC-Mpu-066826	Mustela putorius furo	82.08	4.00e-150	523.00
IUUC-Mlu-068081	Myotis lucifugus	80.77	2.00e-146	511.00
IUUC-Nle-069734	Nomascus leucogenys	82.41	5.00e-150	523.00
IUUC-Opr-070379	Ochotona princeps	79.80	6.00e-143	500.00
IUUC-Ont-071855	Oreochromis niloticus	82.83	9.00e-147	513.00
IUUC-Ocu-074363	Oryctolagus cuniculus	82.41	6.00e-150	523.00
IUUC-Ola-086489	Oryzias latipes	81.93	4.00e-146	510.00
IUUC-Oga-088323	Otolemur garnettii	82.41	1.00e-148	518.00
IUUC-Oar-090243	Ovis aries	82.08	3.00e-150	524.00
IUUC-Ptr-091374	Pan troglodytes	82.08	8.00e-150	523.00
IUUC-Pan-092115	Papio anubis	82.41	5.00e-150	523.00
IUUC-Psi-093658	Pelodiscus sinensis	82.72	5.00e-136	477.00
IUUC-Pfo-097261	Poecilia formosa	81.93	2.00e-145	508.00
IUUC-Pab-098579	Pongo abelii	82.08	8.00e-150	523.00
IUUC-Pca-100119	Procavia capensis	77.52	4.00e-136	477.00
IUUC-Pva-102111	Pteropus vampyrus	82.35	2.00e-149	521.00
IUUC-Rno-105364	Rattus norvegicus	82.41	5.00e-150	523.00
IUUC-Sha-107005	Sarcophilus harrisii	82.41	6.00e-150	523.00
IUUC-Sar-113163	Sorex araneus	82.41	4.00e-150	524.00
IUUC-Ssc-115633	Sus scrofa	80.84	4.00e-147	514.00
IUUC-Tgu-116869	Taeniopygia guttata	82.65	3.00e-142	497.00
IUUC-Tru-118217	Takifugu rubripes	80.36	4.00e-154	537.00
IUUC-Tsy-119308	Tarsius syrichta	82.41	6.00e-150	523.00
IUUC-Tni-119882	Tetraodon nigroviridis	78.81	1.00e-151	528.00
IUUC-Ttr-129087	Tursiops truncatus	82.35	9.00e-150	522.00
IUUC-Vpa-130785	Vicugna pacos	81.57	1.00e-139	489.00
IUUC-Xtr-132801	Xenopus tropicalis	81.97	2.00e-141	494.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence