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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046644
Ensembl Protein ID ENSP00000306410.5
UniProt Accession Q5T2S8; A8K906; B7Z7I1; Q9H0C0; ARMC4_HUMAN
Genbank Protein ID BAF85210.1; BAH13617.1; EAW86050.1; AAI40847.1; CAB66793.2
Protein Name Armadillo repeat-containing protein 4
Genbank Nucleotide ID AK292521; AK302048; AC024606; BC140846; AL136859
Gene Name ARMC4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000169126.15 ENST00000305242.9 ENSP00000306410.5
ENSG00000169126.15 ENST00000434029.1 ENSP00000398155.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmicroRNATRANSFACTargetScan
RepTarmiRNAMapSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDMenthaInWeb_IM
Disease-associated Variation
ClinVarGWASdbOMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusUniProt
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/U-box 30.88 2.00e-08 59.30 IUUC-Ath-007483
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly.
 Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly.
Protein Sequence
(Fasta)
MGVALRKLTQ WTAAGHGTGI LEITPLNEAI LKEIIVFVES FIYKHPQEAK FVFVEPLEWN 60
TSLAPSAFES GYVVSETTVK SEEVDKNGQP LLFLSVPQIK IRSFGQLSRL LLIAKTGKLK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046644|E3,U-box|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATACGGTGCA ACGGGTCCGC GGGAATCTTG GATGCGCGGA GGTCCCGAGA CCAGGGTAAC 60
GGACTGGGCT GCGGTCGCGG CCGGGTGAGG CTGGGAGCGG AAGGCGGCGG CGGCGGCGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046644|E3,U-box|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0966--Cell projection
KW-1186--Ciliopathy
KW-0969--Cilium
KW-0970--Cilium biogenesis/degradation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-1012--Kartagener syndrome
KW-0488--Methylation
KW-0621--Polymorphism
KW-0990--Primary ciliary dyskinesia
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000225--Armadillo
IPR026959--ARMC4
IPR011987--ATPase_V1-cplx_hsu_C
IPR023231--GSKIP_dom
PROSITE

PS50176--ARM_REPEAT
Pfam

PF00514--Arm
SMART

SM00185--ARM
Gene Ontology

GO:0005930--C:axoneme
GO:0097546--C:ciliary base
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0003341--P:cilium movement
GO:0007368--P:determination of left/right symmetry
GO:0007507--P:heart development
GO:0036158--P:outer dynein arm assembly
GO:0003356--P:regulation of cilium beat frequency
GO:0021591--P:ventricular system development
KEGG hsa:55130
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000414 Aegilops tauschii 28.15 6.00e-07 50.10
IUUC-Aml-001718 Ailuropoda melanoleuca 86.59 0.00e+00 1688.00
IUUC-Atr-002793 Amborella trichopoda 26.04 6.00e-10 60.10
IUUC-Aly-006242 Arabidopsis lyrata 30.88 2.00e-09 57.80
IUUC-Ath-007483 Arabidopsis thaliana 30.88 8.00e-10 58.90
IUUC-Ago-007854 Ashbya gossypii 26.32 3.00e-08 53.90
IUUC-Acl-008113 Aspergillus clavatus 22.34 2.00e-12 67.40
IUUC-Afl-008696 Aspergillus flavus 22.69 7.00e-13 68.90
IUUC-Afu-009117 Aspergillus fumigatus 22.34 3.00e-12 67.00
IUUC-Ani-009476 Aspergillus nidulans 22.59 1.00e-12 68.20
IUUC-Ang-009574 Aspergillus niger 22.66 8.00e-13 68.90
IUUC-Aor-010194 Aspergillus oryzae 22.69 7.00e-13 68.90
IUUC-Ate-010256 Aspergillus terreus 22.94 1.00e-13 71.60
IUUC-Ame-010822 Astyanax mexicanus 22.73 3.00e-06 48.50
IUUC-Bgr-012235 Blumeria graminis 24.20 1.00e-13 71.20
IUUC-Bta-013555 Bos taurus 36.73 6.00e-03 37.40
IUUC-Bci-013587 Botrytis cinerea 23.34 7.00e-15 75.50
IUUC-Bol-015195 Brassica oleracea 25.00 2.00e-09 58.20
IUUC-Bra-016628 Brassica rapa 26.06 4.00e-10 60.10
IUUC-Cel-018336 Caenorhabditis elegans 31.58 4.40e-02 34.30
IUUC-Cja-019770 Callithrix jacchus 31.52 3.00e-03 36.20
IUUC-Cpo-021441 Cavia porcellus 82.49 0.00e+00 1674.00
IUUC-Csa-023874 Chlorocebus sabaeus 96.19 0.00e+00 1698.00
IUUC-Cho-024666 Choloepus hoffmanni 22.88 1.00e-03 37.70
IUUC-Cin-025796 Ciona intestinalis 75.70 0.00e+00 932.00
IUUC-Csv-025821 Ciona savignyi 59.87 0.00e+00 1193.00
IUUC-Cgl-026537 Colletotrichum gloeosporioides 22.87 4.00e-15 76.60
IUUC-Cme-027156 Cyanidioschyzon merolae 22.97 1.30e-02 35.00
IUUC-Dme-031688 Drosophila melanogaster 46.37 8.00e-156 543.00
IUUC-Ete-032470 Echinops telfairi 85.93 0.00e+00 795.00
IUUC-Fca-035957 Felis catus 84.00 0.00e+00 1718.00
IUUC-Fox-037811 Fusarium oxysporum 23.08 1.00e-13 72.00
IUUC-Fso-038217 Fusarium solani 23.67 1.00e-11 64.70
IUUC-Ggr-039908 Gaeumannomyces graminis 22.46 7.00e-11 62.40
IUUC-Gac-041812 Gasterosteus aculeatus 32.58 5.00e-03 37.40
IUUC-Ggo-045030 Gorilla gorilla 35.85 3.00e-03 38.50
IUUC-Itr-048617 Ictidomys tridecemlineatus 84.69 0.00e+00 1542.00
IUUC-Kpa-049403 Komagataella pastoris 25.16 5.00e-14 72.80
IUUC-Lpe-051066 Leersia perrieri 22.93 2.00e-10 61.60
IUUC-Loc-051960 Lepisosteus oculatus 25.22 2.90e-02 33.50
IUUC-Lma-053243 Leptosphaeria maculans 27.98 7.00e-13 69.30
IUUC-Mcc-055873 Macaca mulatta 97.45 0.00e+00 860.00
IUUC-Meu-056121 Macropus eugenii 30.91 1.60e-02 35.80
IUUC-Mor-056956 Magnaporthe oryzae 24.78 4.00e-12 66.60
IUUC-Mpo-057354 Magnaporthe poae 22.46 8.00e-11 62.00
IUUC-Mla-058925 Melampsora laricipopulina 28.33 1.00e-08 55.10
IUUC-Mga-059688 Meleagris gallopavo 67.84 0.00e+00 1352.00
IUUC-Mvi-060440 Microbotryum violaceum 24.61 7.00e-04 38.90
IUUC-Mmr-061778 Microcebus murinus 26.04 8.00e-08 51.60
IUUC-Mlu-067208 Myotis lucifugus 36.73 6.00e-03 37.40
IUUC-Nfi-068421 Neosartorya fischeri 27.46 4.00e-12 66.60
IUUC-Ncr-068835 Neurospora crassa 23.87 1.00e-14 74.70
IUUC-Opr-070282 Ochotona princeps 71.87 0.00e+00 1026.00
IUUC-Ocu-074455 Oryctolagus cuniculus 83.26 0.00e+00 1472.00
IUUC-Oga-088587 Otolemur garnettii 35.85 3.00e-03 38.50
IUUC-Ptr-090915 Pan troglodytes 98.56 0.00e+00 1976.00
IUUC-Pan-092171 Papio anubis 93.88 0.00e+00 1845.00
IUUC-Pma-094694 Petromyzon marinus 25.36 4.00e-04 40.40
IUUC-Pno-095110 Phaeosphaeria nodorum 26.94 1.00e-11 65.10
IUUC-Pca-100151 Procavia capensis 58.72 0.00e+00 773.00
IUUC-Pte-104314 Pyrenophora teres 22.81 3.00e-13 70.10
IUUC-Pyt-104569 Pyrenophora triticirepentis 23.37 2.00e-11 64.30
IUUC-Sce-106415 Saccharomyces cerevisiae 24.03 3.00e-13 70.10
IUUC-Sha-107173 Sarcophilus harrisii 35.85 3.00e-03 38.10
IUUC-Sja-107762 Schizosaccharomyces japonicus 22.77 9.00e-12 65.50
IUUC-Spo-108349 Schizosaccharomyces pombe 21.55 3.00e-10 60.10
IUUC-Ssl-108596 Sclerotinia sclerotiorum 23.08 1.00e-13 71.60
IUUC-Sar-113307 Sorex araneus 38.57 1.70e-02 35.00
IUUC-Ssc-116061 Sus scrofa 22.52 2.00e-13 72.00
IUUC-Tru-118154 Takifugu rubripes 28.68 2.00e-03 38.90
IUUC-Tni-120112 Tetraodon nigroviridis 30.43 1.00e-03 39.30
IUUC-Tre-122117 Trichoderma reesei 24.14 1.00e-13 71.20
IUUC-Tvi-122426 Trichoderma virens 22.55 2.00e-13 70.90
IUUC-Tur-126716 Triticum urartu 28.15 6.00e-07 49.70
IUUC-Tme-127103 Tuber melanosporum 22.34 1.00e-12 67.80
IUUC-Tbe-127613 Tupaia belangeri 22.54 5.00e-10 60.80
IUUC-Ttr-128612 Tursiops truncatus 23.30 4.00e-16 81.30
IUUC-Uma-129348 Ustilago maydis 24.87 3.00e-06 47.00
IUUC-Vda-129796 Verticillium dahliae 22.81 2.00e-12 67.80
IUUC-Vpa-130794 Vicugna pacos 30.91 2.80e-02 35.00
IUUC-Vvi-131166 Vitis vinifera 31.39 5.00e-10 59.30
IUUC-Xtr-132376 Xenopus tropicalis 23.50 1.00e-13 73.20
Created Date 25-Jun-2017

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