iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088285

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03108207

Gene Name

TRIM50

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000002366.2	ENSOGAT00000002370.2	ENSOGAP00000002116.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.30e-08	33.6	16	57
E3 activity/RING/U-box	1.10e-08	35.0	12	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCle fk+ pl l+CgH +++dCl   + l++ +  + rCP+Cr
   Q: 16   CPICLEVFKE-PLMLQCGHSYCKDCL---VSLSCHQDAKLRCPVCR 57
           ********99.999************...677999**********8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk....tcPvtrqplteedlvPnltlrrliqa 67
           +++ CpI le++++P +l++G++y + ++     s+++     cPv+rq ++ ++  Pn +l r+i+a
   Q: 12   DQLQCPICLEVFKEPLMLQCGHSYCKDCLVSL--SCHQdaklRCPVCRQAVDGSSSPPNVSLARVIEA 77
           6899***********************99873..333334569**********************987 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAWQVRVLEL EDQLQCPICL EVFKEPLMLQ CGHSYCKDCL VSLSCHQDAK LRCPVCRQAV 60
DGSSSPPNVS LARVIEALRL PGDPEPKVCV HHRNPLSLFC EKDQELICGL CGLLGSHQHH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTGGC AGGTGAGAGT TCTGGAGCTG GAGGACCAGC TTCAGTGTCC CATCTGCCTG 60
GAGGTCTTCA AGGAGCCCCT GATGCTGCAG TGTGGCCACT CCTACTGCAA AGACTGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0016235--C:aggresome
GO:0008270--F:zinc ion binding
GO:0070201--P:regulation of establishment of protein localization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001406	Ailuropoda melanoleuca	88.91	0.00e+00	889.00
IUUC-Apl-004051	Anas platyrhynchos	62.93	2.00e-177	615.00
IUUC-Ame-010964	Astyanax mexicanus	53.94	8.00e-155	540.00
IUUC-Bta-012642	Bos taurus	88.91	0.00e+00	866.00
IUUC-Cja-019011	Callithrix jacchus	87.77	0.00e+00	818.00
IUUC-Cfa-020270	Canis familiaris	87.06	0.00e+00	876.00
IUUC-Cpo-022458	Cavia porcellus	87.61	0.00e+00	851.00
IUUC-Csa-023478	Chlorocebus sabaeus	89.75	0.00e+00	883.00
IUUC-Dno-028894	Dasypus novemcinctus	87.96	0.00e+00	848.00
IUUC-Dor-030228	Dipodomys ordii	83.23	0.00e+00	728.00
IUUC-Eca-033497	Equus caballus	88.50	0.00e+00	885.00
IUUC-Eeu-034910	Erinaceus europaeus	74.67	5.00e-133	466.00
IUUC-Fca-036164	Felis catus	88.91	0.00e+00	894.00
IUUC-Gga-040573	Gallus gallus	55.78	1.00e-96	347.00
IUUC-Ggo-044471	Gorilla gorilla	90.97	0.00e+00	894.00
IUUC-Hsa-046039	Homo sapiens	90.35	0.00e+00	889.00
IUUC-Itr-048897	Ictidomys tridecemlineatus	86.77	0.00e+00	828.00
IUUC-Lch-050638	Latimeria chalumnae	55.60	1.00e-159	556.00
IUUC-Loc-051971	Lepisosteus oculatus	53.86	1.00e-153	536.00
IUUC-Laf-054291	Loxodonta africana	88.27	0.00e+00	847.00
IUUC-Mcc-055708	Macaca mulatta	89.96	0.00e+00	884.00
IUUC-Meu-056670	Macropus eugenii	72.05	8.00e-141	493.00
IUUC-Mla-059039	Melampsora laricipopulina	38.81	2.00e-09	57.00
IUUC-Mga-059415	Meleagris gallopavo	61.42	2.00e-177	615.00
IUUC-Mmr-061410	Microcebus murinus	93.76	0.00e+00	874.00
IUUC-Mmu-064094	Mus musculus	87.39	0.00e+00	857.00
IUUC-Mpu-065781	Mustela putorius furo	87.06	0.00e+00	872.00
IUUC-Mlu-067974	Myotis lucifugus	88.09	0.00e+00	861.00
IUUC-Nle-069000	Nomascus leucogenys	90.14	0.00e+00	888.00
IUUC-Opr-071216	Ochotona princeps	87.91	1.00e-112	399.00
IUUC-Ocu-074859	Oryctolagus cuniculus	86.45	0.00e+00	837.00
IUUC-Oar-090161	Ovis aries	79.30	0.00e+00	763.00
IUUC-Ptr-091672	Pan troglodytes	90.55	0.00e+00	890.00
IUUC-Pan-092870	Papio anubis	89.96	0.00e+00	884.00
IUUC-Psi-093742	Pelodiscus sinensis	65.68	0.00e+00	661.00
IUUC-Pab-098034	Pongo abelii	90.55	0.00e+00	891.00
IUUC-Pca-100115	Procavia capensis	83.64	7.00e-72	263.00
IUUC-Pva-103234	Pteropus vampyrus	89.34	0.00e+00	865.00
IUUC-Rno-105163	Rattus norvegicus	86.97	0.00e+00	844.00
IUUC-Sha-106575	Sarcophilus harrisii	63.62	2.00e-158	551.00
IUUC-Ssc-115600	Sus scrofa	88.09	0.00e+00	882.00
IUUC-Tbe-128151	Tupaia belangeri	92.90	3.00e-98	350.00
IUUC-Ttr-128947	Tursiops truncatus	87.27	0.00e+00	848.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence