iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117402

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01051084

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000001234.1	ENSTGUT00000001299.1	ENSTGUP00000001287.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.60e-19	69.9	14	77
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.90e-13	49.3	113	144

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv++ v+ + f+ah+ivLaa+S++F a+f++el+e++ k++v+i+++ ++ ++ ll+F+Yt ++
   Q: 14   CDVTIRVEHKDFPAHRIVLAACSDYFCAMFTSELSEKD-KPCVDIQGLTASTMEILLDFVYTETV 77
           9************************************9.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fA++++c dL++aa+ f +khF+
   Q: 113  PSNCLGIRDFAETHNCVDLMQAAEVFSQKHFP 144
           89*****************************6 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

LNAMNALRKS NTFCDVTIRV EHKDFPAHRI VLAACSDYFC AMFTSELSEK DKPCVDIQGL 60
TASTMEILLD FVYTETVHVT VENVQELLPA ACLLQLKGVK QACCEFLESQ LDPSNCLGIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAACGCCA TGAACGCCTT GCGTAAGAGC AACACGTTCT GCGACGTCAC CATCCGCGTG 60
GAGCACAAGG ACTTCCCGGC CCACCGCATC GTCCTGGCCG CCTGCAGCGA CTACTTCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0030134--C:ER to Golgi transport vesicle
GO:0000139--C:Golgi membrane
GO:0005815--C:microtubule organizing center
GO:0048208--P:COPII vesicle coating
GO:0006513--P:protein monoubiquitination
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002301	Ailuropoda melanoleuca	74.39	0.00e+00	768.00
IUUC-Atr-002726	Amborella trichopoda	38.14	3.00e-44	173.00
IUUC-Apl-003339	Anas platyrhynchos	75.25	0.00e+00	721.00
IUUC-Aca-004418	Anolis carolinensis	75.33	0.00e+00	772.00
IUUC-Ang-009879	Aspergillus niger	27.88	1.00e-08	53.10
IUUC-Bta-012979	Bos taurus	73.63	0.00e+00	757.00
IUUC-Cja-019582	Callithrix jacchus	74.58	0.00e+00	766.00
IUUC-Cfa-020716	Canis familiaris	74.58	0.00e+00	766.00
IUUC-Cpo-022013	Cavia porcellus	74.76	0.00e+00	768.00
IUUC-Csa-023424	Chlorocebus sabaeus	73.58	0.00e+00	723.00
IUUC-Cho-024586	Choloepus hoffmanni	56.31	1.00e-151	529.00
IUUC-Dre-028344	Danio rerio	80.00	2.00e-139	487.00
IUUC-Dno-028854	Dasypus novemcinctus	74.58	0.00e+00	766.00
IUUC-Dor-030403	Dipodomys ordii	74.39	0.00e+00	762.00
IUUC-Ete-032963	Echinops telfairi	71.13	0.00e+00	650.00
IUUC-Eca-033282	Equus caballus	74.39	0.00e+00	766.00
IUUC-Fca-035487	Felis catus	74.58	0.00e+00	766.00
IUUC-Fal-037059	Ficedula albicollis	76.65	0.00e+00	786.00
IUUC-Gmo-039564	Gadus morhua	68.30	0.00e+00	739.00
IUUC-Gga-040629	Gallus gallus	76.27	0.00e+00	783.00
IUUC-Gac-042526	Gasterosteus aculeatus	68.30	0.00e+00	738.00
IUUC-Gma-043533	Glycine max	33.46	2.00e-38	153.00
IUUC-Ggo-044839	Gorilla gorilla	74.58	0.00e+00	766.00
IUUC-Hsa-046742	Homo sapiens	74.58	0.00e+00	766.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	74.58	0.00e+00	767.00
IUUC-Lch-049540	Latimeria chalumnae	72.37	0.00e+00	773.00
IUUC-Loc-051923	Lepisosteus oculatus	71.89	0.00e+00	748.00
IUUC-Laf-054370	Loxodonta africana	74.76	0.00e+00	768.00
IUUC-Mcc-054852	Macaca mulatta	74.58	0.00e+00	766.00
IUUC-Mga-059486	Meleagris gallopavo	73.23	0.00e+00	711.00
IUUC-Mmr-061777	Microcebus murinus	74.58	0.00e+00	764.00
IUUC-Mdo-061990	Monodelphis domestica	73.63	0.00e+00	757.00
IUUC-Mmu-064053	Mus musculus	74.39	0.00e+00	766.00
IUUC-Mac-064682	Musa acuminata	39.81	1.00e-44	174.00
IUUC-Mpu-066623	Mustela putorius furo	78.92	0.00e+00	687.00
IUUC-Mlu-067648	Myotis lucifugus	73.82	0.00e+00	786.00
IUUC-Nle-069714	Nomascus leucogenys	74.39	0.00e+00	765.00
IUUC-Opr-071143	Ochotona princeps	72.26	0.00e+00	737.00
IUUC-Ont-071848	Oreochromis niloticus	69.06	0.00e+00	746.00
IUUC-Oan-073041	Ornithorhynchus anatinus	94.57	2.00e-146	510.00
IUUC-Ocu-074379	Oryctolagus cuniculus	74.58	0.00e+00	764.00
IUUC-Obr-076712	Oryza brachyantha	35.78	1.00e-32	134.00
IUUC-Ola-087469	Oryzias latipes	68.68	0.00e+00	743.00
IUUC-Oar-090144	Ovis aries	74.20	0.00e+00	764.00
IUUC-Ptr-091406	Pan troglodytes	74.58	0.00e+00	766.00
IUUC-Pan-092762	Papio anubis	74.44	0.00e+00	757.00
IUUC-Psi-093391	Pelodiscus sinensis	74.95	0.00e+00	769.00
IUUC-Pma-094134	Petromyzon marinus	55.43	3.00e-159	554.00
IUUC-Pfo-096404	Poecilia formosa	68.93	0.00e+00	741.00
IUUC-Pab-098425	Pongo abelii	74.01	0.00e+00	757.00
IUUC-Pca-101093	Procavia capensis	87.33	5.00e-149	520.00
IUUC-Ppe-101154	Prunus persica	33.08	2.00e-38	154.00
IUUC-Pva-102239	Pteropus vampyrus	67.11	0.00e+00	692.00
IUUC-Rno-104921	Rattus norvegicus	74.58	0.00e+00	767.00
IUUC-Sha-106625	Sarcophilus harrisii	74.39	0.00e+00	765.00
IUUC-Sar-113468	Sorex araneus	64.32	5.00e-134	470.00
IUUC-Sbi-114612	Sorghum bicolor	35.32	1.00e-34	141.00
IUUC-Ssc-116106	Sus scrofa	74.20	0.00e+00	763.00
IUUC-Tru-117546	Takifugu rubripes	68.17	0.00e+00	738.00
IUUC-Tsy-118802	Tarsius syrichta	67.72	0.00e+00	639.00
IUUC-Tni-119999	Tetraodon nigroviridis	68.74	0.00e+00	742.00
IUUC-Tca-121074	Theobroma cacao	32.95	2.00e-38	154.00
IUUC-Tae-124761	Triticum aestivum	35.35	3.00e-38	153.00
IUUC-Tbe-127987	Tupaia belangeri	70.09	0.00e+00	625.00
IUUC-Ttr-128613	Tursiops truncatus	66.85	0.00e+00	662.00
IUUC-Xtr-132401	Xenopus tropicalis	82.37	5.00e-145	506.00
IUUC-Xma-134289	Xiphophorus maculatus	68.93	0.00e+00	741.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence