iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004253

UUCD1 version

UUC-AnC-00743

Ensembl Protein ID

ENSACAP00000012364.2

UniProt Accession

G1KMJ1; G1KMJ1_ANOCA

Protein Name

Uncharacterized protein

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000012616.3	ENSACAT00000012617.3	ENSACAP00000012364.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	71.95	1.00e-70	263.00	IUUC-Hsa-046557

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MTLRSEETSD GGGEEEAPGE AERLDSAMRE LRRAGWYWGN MSVAEAKDRL QDTSEGTFLV 60
RDSSHSEYLL TISVKTSAGP TNLRIEFQDG KFRLDSIICV RSRLRQFDSV VHLIEYYVLM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACATTGGCA TGTTTTCGAA CTACTAGGTT GGCAGGAGCT GGAGCAACAG CGGGCGCTCA 60
CTCCACTCCC GGGATTTGAA CCTGGGACCT TTCGGTCTGC AAGTTCAGCA CACACTTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

KEGG

acs:100552196

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	70.55	5.00e-70	256.00
IUUC-Apl-003484	Anas platyrhynchos	84.31	4.00e-76	276.00
IUUC-Ame-011267	Astyanax mexicanus	56.97	2.00e-54	204.00
IUUC-Bta-013183	Bos taurus	72.37	9.00e-68	249.00
IUUC-Cja-018862	Callithrix jacchus	72.08	2.00e-68	251.00
IUUC-Cfa-020226	Canis familiaris	73.03	1.00e-67	248.00
IUUC-Cpo-022414	Cavia porcellus	74.34	1.00e-68	251.00
IUUC-Csa-023758	Chlorocebus sabaeus	72.08	4.00e-68	249.00
IUUC-Cho-024471	Choloepus hoffmanni	66.88	4.00e-56	210.00
IUUC-Dre-028288	Danio rerio	59.52	3.00e-58	217.00
IUUC-Dno-029036	Dasypus novemcinctus	71.78	5.00e-71	259.00
IUUC-Dor-030447	Dipodomys ordii	73.51	6.00e-67	245.00
IUUC-Ete-033023	Echinops telfairi	71.95	3.00e-72	264.00
IUUC-Fca-036469	Felis catus	72.08	4.00e-68	250.00
IUUC-Fal-036642	Ficedula albicollis	78.75	2.00e-74	270.00
IUUC-Gmo-039331	Gadus morhua	63.04	4.00e-33	132.00
IUUC-Gga-040809	Gallus gallus	85.53	7.00e-80	288.00
IUUC-Gac-041398	Gasterosteus aculeatus	58.18	1.00e-54	205.00
IUUC-Ggo-045341	Gorilla gorilla	72.73	1.00e-68	251.00
IUUC-Hsa-046557	Homo sapiens	71.95	5.00e-72	263.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	70.97	6.00e-68	249.00
IUUC-Lch-050160	Latimeria chalumnae	59.18	2.00e-51	194.00
IUUC-Loc-051825	Lepisosteus oculatus	57.58	4.00e-58	216.00
IUUC-Laf-053560	Loxodonta africana	72.08	3.00e-68	250.00
IUUC-Mcc-055890	Macaca mulatta	72.08	8.00e-68	249.00
IUUC-Meu-056218	Macropus eugenii	73.17	4.00e-73	266.00
IUUC-Mga-059755	Meleagris gallopavo	85.53	1.00e-76	278.00
IUUC-Mmr-061387	Microcebus murinus	72.08	3.00e-68	250.00
IUUC-Mdo-062383	Monodelphis domestica	73.78	1.00e-73	268.00
IUUC-Mmu-063443	Mus musculus	70.78	4.00e-67	246.00
IUUC-Mpu-066459	Mustela putorius furo	70.78	4.00e-66	243.00
IUUC-Mlu-068040	Myotis lucifugus	71.17	9.00e-71	259.00
IUUC-Nle-069016	Nomascus leucogenys	69.51	7.00e-69	252.00
IUUC-Opr-071087	Ochotona princeps	68.29	2.00e-67	247.00
IUUC-Ont-072340	Oreochromis niloticus	57.31	9.00e-58	215.00
IUUC-Oan-073443	Ornithorhynchus anatinus	75.46	4.00e-74	270.00
IUUC-Ocu-074539	Oryctolagus cuniculus	70.59	1.00e-65	242.00
IUUC-Ola-087004	Oryzias latipes	55.70	6.00e-51	192.00
IUUC-Oga-088438	Otolemur garnettii	71.43	1.00e-67	248.00
IUUC-Oar-089932	Ovis aries	73.68	1.00e-68	251.00
IUUC-Ptr-091037	Pan troglodytes	72.73	1.00e-68	251.00
IUUC-Pan-092767	Papio anubis	72.08	5.00e-68	249.00
IUUC-Psi-093099	Pelodiscus sinensis	83.02	3.00e-78	283.00
IUUC-Pfo-097073	Poecilia formosa	53.61	2.00e-52	198.00
IUUC-Pab-098319	Pongo abelii	71.78	4.00e-71	260.00
IUUC-Pca-101117	Procavia capensis	72.08	2.00e-67	247.00
IUUC-Pva-102117	Pteropus vampyrus	72.37	4.00e-67	246.00
IUUC-Rno-105913	Rattus norvegicus	70.78	9.00e-68	249.00
IUUC-Sha-106500	Sarcophilus harrisii	74.23	2.00e-73	268.00
IUUC-Ssc-115252	Sus scrofa	73.03	5.00e-68	249.00
IUUC-Tgu-117524	Taeniopygia guttata	82.39	3.00e-77	280.00
IUUC-Tsy-119335	Tarsius syrichta	73.51	3.00e-67	246.00
IUUC-Tni-120263	Tetraodon nigroviridis	55.29	1.00e-53	202.00
IUUC-Tbe-127915	Tupaia belangeri	72.08	7.00e-68	249.00
IUUC-Ttr-128372	Tursiops truncatus	73.03	7.00e-68	249.00
IUUC-Vpa-130422	Vicugna pacos	72.85	5.00e-67	245.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence