iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020486

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03015407

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000007266.3	ENSCAFT00000011650.3	ENSCAFP00000010795.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.30e-103	344.8	307	645

Active Site

Position(s)	Description	Evidence
613	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G+l+g+a++++  ld+
   Q: 307  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKC-----DNYSEFRLVGILMGLAVYNSITLDI 390
           589***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++ +dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k+++LkpgG++ipV
   Q: 391  RFPPCCYKKLLSPpiipsdqnipvgicSVTTDDLCQIMPELAHGLSELLSY-EGNVEED-FYSTFQVFQEEFGIIKSYNLKPGGDKIPV 477
           *************666666666665555**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l++++ l+++i +q++af+ Gf++v+  + l l+++ee+e+l+cG++e+d+ +l++ t+y+g y +++ +i++Fw+v+ 
   Q: 478  TNQNRKEYVQLYIDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPELDMYALQRSTQYDG-YAKTDLTIRYFWDVVL 565
           **********************************************************************76.**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y+sk+ lk+kL++ i++++gF+l+
   Q: 566  GFPLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKnETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE 645
           *****************************...9999967777**************************************985 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MKDFQEDVEK AKSTGDWKAV HDFYLTTFDS FPELNAAFKK DATASFNTIE DSGINAKFVN 60
AVYDALLNTP QDIQKTVLKG IINSLLREWK GPRTKDDLRA YFILLQNPQF NNTSTYVIYA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNCCGACATG AGTGAAGAGG GCCCGTTGAG GGCGCCCGCC GGGCCGCCCG AGCTGGCGGC 60
GGCCTCTTCG GAGGACAGGA AGGGAAGGGA GCCGGAGCGC GAGAAGCTGC CGCCCATCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	98.15	0.00e+00	1307.00
IUUC-Apl-003589	Anas platyrhynchos	89.15	0.00e+00	1171.00
IUUC-Aca-004350	Anolis carolinensis	84.81	0.00e+00	1137.00
IUUC-Ago-007908	Ashbya gossypii	34.86	1.00e-79	291.00
IUUC-Acl-008288	Aspergillus clavatus	35.53	5.00e-95	343.00
IUUC-Afl-008402	Aspergillus flavus	34.16	6.00e-89	322.00
IUUC-Afu-008762	Aspergillus fumigatus	34.32	2.00e-91	331.00
IUUC-Ani-009176	Aspergillus nidulans	35.55	4.00e-91	329.00
IUUC-Ang-009791	Aspergillus niger	35.87	5.00e-91	329.00
IUUC-Aor-009921	Aspergillus oryzae	34.00	4.00e-88	319.00
IUUC-Ate-010295	Aspergillus terreus	36.29	1.00e-98	354.00
IUUC-Ame-010660	Astyanax mexicanus	83.28	6.00e-154	536.00
IUUC-Bgr-011981	Blumeria graminis	32.29	2.00e-91	331.00
IUUC-Bta-012945	Bos taurus	96.74	0.00e+00	1266.00
IUUC-Bci-013697	Botrytis cinerea	33.22	8.00e-78	285.00
IUUC-Cja-019263	Callithrix jacchus	96.92	0.00e+00	1268.00
IUUC-Cpo-021755	Cavia porcellus	97.21	0.00e+00	1297.00
IUUC-Csa-023814	Chlorocebus sabaeus	97.03	0.00e+00	1188.00
IUUC-Cho-024980	Choloepus hoffmanni	77.21	0.00e+00	965.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	41.35	3.00e-95	343.00
IUUC-Dre-028551	Danio rerio	81.06	0.00e+00	1077.00
IUUC-Dno-029497	Dasypus novemcinctus	93.98	0.00e+00	1199.00
IUUC-Dor-030867	Dipodomys ordii	82.33	0.00e+00	1059.00
IUUC-Dse-031239	Dothistroma septosporum	30.80	8.00e-87	315.00
IUUC-Ete-032902	Echinops telfairi	92.01	0.00e+00	1092.00
IUUC-Eca-033678	Equus caballus	97.52	0.00e+00	1301.00
IUUC-Eeu-035262	Erinaceus europaeus	83.17	0.00e+00	990.00
IUUC-Fca-035590	Felis catus	98.45	0.00e+00	1333.00
IUUC-Fal-037123	Ficedula albicollis	85.23	0.00e+00	1105.00
IUUC-Fox-037941	Fusarium oxysporum	41.08	9.00e-99	355.00
IUUC-Fso-038388	Fusarium solani	40.87	1.00e-100	361.00
IUUC-Gmo-039553	Gadus morhua	66.61	0.00e+00	850.00
IUUC-Ggr-040110	Gaeumannomyces graminis	40.67	2.00e-96	347.00
IUUC-Gga-040406	Gallus gallus	89.30	0.00e+00	1201.00
IUUC-Gac-042141	Gasterosteus aculeatus	77.47	0.00e+00	1059.00
IUUC-Ggo-045504	Gorilla gorilla	95.99	0.00e+00	1256.00
IUUC-Hsa-045786	Homo sapiens	96.43	0.00e+00	1261.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	90.73	0.00e+00	1161.00
IUUC-Kpa-049152	Komagataella pastoris	34.17	1.00e-74	274.00
IUUC-Lch-049824	Latimeria chalumnae	84.32	0.00e+00	1025.00
IUUC-Loc-052173	Lepisosteus oculatus	83.57	0.00e+00	1145.00
IUUC-Laf-054017	Loxodonta africana	96.90	0.00e+00	1272.00
IUUC-Mcc-055713	Macaca mulatta	96.61	0.00e+00	1260.00
IUUC-Meu-056212	Macropus eugenii	69.75	2.00e-116	412.00
IUUC-Mor-057045	Magnaporthe oryzae	38.51	4.00e-88	320.00
IUUC-Mla-059187	Melampsora laricipopulina	43.74	8.00e-87	313.00
IUUC-Mga-059884	Meleagris gallopavo	81.76	0.00e+00	1047.00
IUUC-Mmr-061344	Microcebus murinus	96.90	0.00e+00	1291.00
IUUC-Mdo-062653	Monodelphis domestica	92.87	0.00e+00	1224.00
IUUC-Mmu-063775	Mus musculus	93.19	0.00e+00	1206.00
IUUC-Mpu-066069	Mustela putorius furo	98.45	0.00e+00	1330.00
IUUC-Mlu-067925	Myotis lucifugus	97.67	0.00e+00	1280.00
IUUC-Nfi-068439	Neosartorya fischeri	34.15	1.00e-91	331.00
IUUC-Ncr-068903	Neurospora crassa	37.68	1.00e-90	328.00
IUUC-Nle-070046	Nomascus leucogenys	96.30	0.00e+00	1285.00
IUUC-Opr-071085	Ochotona princeps	79.53	2.00e-136	479.00
IUUC-Ont-072126	Oreochromis niloticus	78.57	0.00e+00	1082.00
IUUC-Oan-072933	Ornithorhynchus anatinus	89.30	0.00e+00	1170.00
IUUC-Ocu-073800	Oryctolagus cuniculus	97.05	0.00e+00	1269.00
IUUC-Ola-086988	Oryzias latipes	77.67	0.00e+00	1064.00
IUUC-Oga-088117	Otolemur garnettii	96.55	0.00e+00	1129.00
IUUC-Oar-089371	Ovis aries	96.90	0.00e+00	1246.00
IUUC-Ptr-090551	Pan troglodytes	95.84	0.00e+00	1256.00
IUUC-Pan-092067	Papio anubis	97.21	0.00e+00	1267.00
IUUC-Psi-092963	Pelodiscus sinensis	90.08	0.00e+00	1187.00
IUUC-Pfo-096562	Poecilia formosa	76.55	0.00e+00	1059.00
IUUC-Pab-098680	Pongo abelii	96.74	0.00e+00	1264.00
IUUC-Pca-100986	Procavia capensis	76.67	0.00e+00	899.00
IUUC-Pva-102219	Pteropus vampyrus	86.33	0.00e+00	1033.00
IUUC-Pgr-103315	Puccinia graminis	36.27	4.00e-95	342.00
IUUC-Ptt-103736	Puccinia triticina	41.91	4.00e-94	339.00
IUUC-Rno-105270	Rattus norvegicus	93.64	0.00e+00	1211.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.65	4.00e-68	253.00
IUUC-Sha-106819	Sarcophilus harrisii	93.19	0.00e+00	1242.00
IUUC-Spo-108271	Schizosaccharomyces pombe	32.63	4.00e-85	309.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	31.09	7.00e-83	302.00
IUUC-Sar-113134	Sorex araneus	86.98	0.00e+00	1125.00
IUUC-Ssc-115441	Sus scrofa	97.37	0.00e+00	1279.00
IUUC-Tgu-117166	Taeniopygia guttata	88.06	0.00e+00	1157.00
IUUC-Tsy-118898	Tarsius syrichta	83.64	0.00e+00	1025.00
IUUC-Tre-122108	Trichoderma reesei	39.03	4.00e-88	320.00
IUUC-Tvi-122644	Trichoderma virens	39.31	2.00e-93	337.00
IUUC-Tme-127004	Tuber melanosporum	34.71	1.00e-101	365.00
IUUC-Tbe-127292	Tupaia belangeri	77.83	0.00e+00	950.00
IUUC-Ttr-128352	Tursiops truncatus	92.87	0.00e+00	1194.00
IUUC-Vda-129969	Verticillium dahliae	40.66	3.00e-91	330.00
IUUC-Vpa-130218	Vicugna pacos	94.93	0.00e+00	885.00
IUUC-Xtr-132594	Xenopus tropicalis	81.24	0.00e+00	1046.00
IUUC-Xma-134157	Xiphophorus maculatus	76.53	0.00e+00	986.00
IUUC-Yli-134470	Yarrowia lipolytica	31.02	4.00e-76	280.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence