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Tag Content
UUCD2 ID IUUC-Aml-001673
UUCD1 version UUC-AiM-00007
Ensembl Protein ID ENSAMEP00000003162.1
UniProt Accession D2GX49; D2GX49_AILME
Genbank Protein ID EFB19858.1
Protein Name Putative uncharacterized protein
Genbank Nucleotide ID ACTA01024648
Gene Name HERC3; PANDA_001437
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000002929.1 ENSAMET00000003292.1 ENSAMEP00000003162.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 5.30e-95 318.7 726 1049
Active Site
Position(s) Description Evidence
1018 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           dlkk l+v f gEe++d+gGvt+ef+ ll+kel np +g+f+y ++++  ++ +         + ++F+++G+ +g+a++++ ++dl
   Q: 726  DLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFV-----EHNWFHLIGITCGLAIYNSTVVDL 807
           899******************************************9999999776554.....579********************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklv 177
           +++ ++yk+ll++k  ledl+e+ p+  +sl+e++++  +diee+ ++l+f++  e++g +++++L+pgG+++ V ++N++e+v+++
   Q: 808  HFPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDIEET-FCLNFTICRESYGVIEQKKLIPGGDKVTVRKDNRQEFVDAY 893
           *******************************************98.******99********************************* PP
   S: 178  veyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
           v+y ++ +++e ++af++Gf +v+  ++l+lF+++el+ ++ G++++++++l++++ ykg+y++++p+++ Fwe+++ef  e++k+f
   Q: 894  VNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWQELEETAVYKGDYSATHPTVKLFWETFHEFPLEKKKKF 980
           *************************************************************************************** PP
   S: 265  LqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           L F+Tgs+r+P+ G+a+l+   +vi+  ++ ++ lP ++TC+n+L+LP+Ysskeil  +L+ A ++ +gF+l
   Q: 981  LLFLTGSDRIPIYGMASLQ---IVIQStASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFSL 1049
           *******************...8888867788**************************************97 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
MLCWGYWSLG QPGISTNLQG IVAEPQVCGF ISDRSVKEVA CGGNHSVFLL EDGEVYTCGL 60
NTKGQLGHER EGNKPEQIGA LADQHIVHVA CGESHSLALS DRGQLFSWGA GSDGQLGLMT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001673|E3,HECT|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTTATGTT GGGGATATTG GTCTCTGGGC CAACCTGGGA TCAGCACCAA CCTGCAGGGG 60
ATTGTGGCCG AGCCACAGGT GTGTGGATTC ATATCTGACA GAAGCGTCAA GGAAGTGGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001673|E3,HECT|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3
Pfam

PF00632--HECT
PF00415--RCC1
PRINTS

PR00633--RCCNDNSATION
SMART

SM00119--HECTc
Gene Ontology

GO:0005829--C:cytosol
GO:0004842--F:ubiquitin-protein transferase activity
KEGG aml:100479794
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003535 Anas platyrhynchos 88.38 0.00e+00 1887.00
IUUC-Aca-005223 Anolis carolinensis 85.52 0.00e+00 1840.00
IUUC-Ame-010816 Astyanax mexicanus 65.92 0.00e+00 1164.00
IUUC-Bta-013373 Bos taurus 97.81 0.00e+00 2082.00
IUUC-Cel-018150 Caenorhabditis elegans 32.93 8.00e-154 538.00
IUUC-Cja-019609 Callithrix jacchus 98.86 0.00e+00 2100.00
IUUC-Cfa-021071 Canis familiaris 99.24 0.00e+00 2100.00
IUUC-Cpo-021548 Cavia porcellus 96.95 0.00e+00 2066.00
IUUC-Csa-023987 Chlorocebus sabaeus 98.95 0.00e+00 2099.00
IUUC-Cho-024325 Choloepus hoffmanni 97.77 0.00e+00 1201.00
IUUC-Dre-027472 Danio rerio 66.35 0.00e+00 1399.00
IUUC-Dno-029241 Dasypus novemcinctus 96.86 0.00e+00 2058.00
IUUC-Dor-030672 Dipodomys ordii 91.86 0.00e+00 1133.00
IUUC-Ete-032642 Echinops telfairi 91.81 0.00e+00 1892.00
IUUC-Eca-033646 Equus caballus 98.67 0.00e+00 2091.00
IUUC-Eeu-035098 Erinaceus europaeus 85.02 0.00e+00 1378.00
IUUC-Fal-036952 Ficedula albicollis 88.10 0.00e+00 1882.00
IUUC-Gmo-039297 Gadus morhua 64.00 0.00e+00 1320.00
IUUC-Gga-040591 Gallus gallus 87.54 0.00e+00 1866.00
IUUC-Gac-041741 Gasterosteus aculeatus 65.28 0.00e+00 1384.00
IUUC-Ggo-044769 Gorilla gorilla 98.86 0.00e+00 2095.00
IUUC-Hsa-046066 Homo sapiens 98.95 0.00e+00 2098.00
IUUC-Itr-048311 Ictidomys tridecemlineatus 98.10 0.00e+00 2080.00
IUUC-Lch-050301 Latimeria chalumnae 73.90 0.00e+00 1630.00
IUUC-Loc-052803 Lepisosteus oculatus 67.25 0.00e+00 1458.00
IUUC-Laf-053364 Loxodonta africana 98.29 0.00e+00 2084.00
IUUC-Mcc-054930 Macaca mulatta 99.05 0.00e+00 2099.00
IUUC-Meu-056274 Macropus eugenii 79.45 0.00e+00 872.00
IUUC-Mtr-058277 Medicago truncatula 37.58 2.00e-52 200.00
IUUC-Mga-059563 Meleagris gallopavo 88.00 0.00e+00 1879.00
IUUC-Mmr-060792 Microcebus murinus 95.90 0.00e+00 2029.00
IUUC-Mdo-062195 Monodelphis domestica 91.44 0.00e+00 1961.00
IUUC-Mmu-063855 Mus musculus 95.14 0.00e+00 2040.00
IUUC-Mpu-066308 Mustela putorius furo 99.52 0.00e+00 2107.00
IUUC-Mlu-066927 Myotis lucifugus 98.00 0.00e+00 2075.00
IUUC-Nle-070090 Nomascus leucogenys 98.95 0.00e+00 2099.00
IUUC-Opr-070891 Ochotona princeps 85.62 0.00e+00 1770.00
IUUC-Ont-072201 Oreochromis niloticus 64.08 0.00e+00 1342.00
IUUC-Ocu-074770 Oryctolagus cuniculus 97.62 0.00e+00 2078.00
IUUC-Ola-086550 Oryzias latipes 65.15 0.00e+00 1390.00
IUUC-Olu-087836 Ostreococcus lucimarinus 34.53 4.00e-42 165.00
IUUC-Oga-088831 Otolemur garnettii 97.81 0.00e+00 2076.00
IUUC-Oar-090449 Ovis aries 97.71 0.00e+00 2074.00
IUUC-Pan-092135 Papio anubis 98.86 0.00e+00 2095.00
IUUC-Psi-093832 Pelodiscus sinensis 85.73 0.00e+00 1883.00
IUUC-Pfo-097268 Poecilia formosa 65.62 0.00e+00 1386.00
IUUC-Pab-098249 Pongo abelii 98.67 0.00e+00 2094.00
IUUC-Pca-100855 Procavia capensis 93.85 0.00e+00 1428.00
IUUC-Pva-102506 Pteropus vampyrus 89.82 0.00e+00 1843.00
IUUC-Rno-105242 Rattus norvegicus 95.43 0.00e+00 2082.00
IUUC-Sha-107186 Sarcophilus harrisii 89.55 0.00e+00 1200.00
IUUC-Sar-113612 Sorex araneus 95.65 0.00e+00 749.00
IUUC-Ssc-115473 Sus scrofa 97.90 0.00e+00 2078.00
IUUC-Tgu-116974 Taeniopygia guttata 88.11 0.00e+00 1860.00
IUUC-Tru-118077 Takifugu rubripes 63.55 0.00e+00 1319.00
IUUC-Tsy-119619 Tarsius syrichta 86.86 0.00e+00 1853.00
IUUC-Tni-120807 Tetraodon nigroviridis 63.74 0.00e+00 1340.00
IUUC-Tbe-127640 Tupaia belangeri 94.19 0.00e+00 1951.00
IUUC-Ttr-129172 Tursiops truncatus 97.24 0.00e+00 2063.00
IUUC-Vpa-130442 Vicugna pacos 83.24 0.00e+00 1705.00
IUUC-Xtr-132194 Xenopus tropicalis 71.36 0.00e+00 1441.00
Created Date 25-Jun-2017

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