iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037293

Ensembl Protein ID

ENSFALP00000011686.1

UniProt Accession

U3K9I2; U3K9I2_FICAL

Genbank Protein ID

ENSFALP00000011686

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010741

Gene Name

KLHL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000011199.1	ENSFALT00000011734.1	ENSFALP00000011686.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.20e-21	75.7	18	85
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.00e-11	42.0	119	147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv++v ++ e+ ah++vLaa+S++F+a+f++e++es+  ++v ik+v+   +r l++++Yt +++ +e
   Q: 18   CDVTIVAEDMEIAAHRVVLAACSPYFHAMFTGEMSESR-AKKVRIKEVDGWTLRMLIDYIYTAEIQVTE 85
           8*************************************.*************************99765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 3    NclgilrfAdlydcpdLkdaaldfilkhF 31
           Nclgi++fAd++ c+dL ++a++++++hF
   Q: 119  NCLGIRAFADMHACTDLLSKANTYAEQHF 147
           ***************************** PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MKKAFKVMNE LRSQNLLCDV TIVAEDMEIA AHRVVLAACS PYFHAMFTGE MSESRAKKVR 60
IKEVDGWTLR MLIDYIYTAE IQVTEENVQV LLPAAGLLQL QDVKRTCCEF LESQLHPINC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTACTACT TCCACGGGAA TTCTACCTAT TCCTTTACAC CTTTGGTAAT AGGGAAACCA 60
AAATTGCTTG AAGTAAAGAA GAAGTTTCAA GTGTGAATCT TCTTCTTCTC CCCAAGATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002378	Ailuropoda melanoleuca	92.61	0.00e+00	1049.00
IUUC-Apl-003260	Anas platyrhynchos	98.92	0.00e+00	1090.00
IUUC-Aca-005143	Anolis carolinensis	88.47	0.00e+00	1035.00
IUUC-Cja-018942	Callithrix jacchus	92.43	0.00e+00	1047.00
IUUC-Cfa-020886	Canis familiaris	92.79	0.00e+00	1051.00
IUUC-Cpo-022543	Cavia porcellus	92.61	0.00e+00	1050.00
IUUC-Csa-023088	Chlorocebus sabaeus	92.79	0.00e+00	1051.00
IUUC-Dre-028082	Danio rerio	83.42	0.00e+00	951.00
IUUC-Dno-029873	Dasypus novemcinctus	90.34	0.00e+00	1027.00
IUUC-Dor-030460	Dipodomys ordii	73.33	0.00e+00	756.00
IUUC-Dse-031229	Dothistroma septosporum	38.57	2.00e-08	52.00
IUUC-Dme-032172	Drosophila melanogaster	61.12	0.00e+00	666.00
IUUC-Eca-033798	Equus caballus	92.25	0.00e+00	1047.00
IUUC-Eeu-034824	Erinaceus europaeus	84.71	0.00e+00	920.00
IUUC-Fca-036455	Felis catus	92.79	0.00e+00	1051.00
IUUC-Gmo-038811	Gadus morhua	79.28	0.00e+00	850.00
IUUC-Gga-040805	Gallus gallus	98.02	0.00e+00	1082.00
IUUC-Gac-041979	Gasterosteus aculeatus	81.44	0.00e+00	850.00
IUUC-Ggo-044620	Gorilla gorilla	87.57	0.00e+00	988.00
IUUC-Hsa-046265	Homo sapiens	92.61	0.00e+00	1050.00
IUUC-Lch-049939	Latimeria chalumnae	84.50	0.00e+00	941.00
IUUC-Loc-052780	Lepisosteus oculatus	87.39	0.00e+00	994.00
IUUC-Laf-053800	Loxodonta africana	92.61	0.00e+00	1049.00
IUUC-Mcc-055732	Macaca mulatta	91.70	0.00e+00	1036.00
IUUC-Meu-056011	Macropus eugenii	92.62	0.00e+00	1025.00
IUUC-Mmr-061067	Microcebus murinus	91.37	0.00e+00	1035.00
IUUC-Mdo-062977	Monodelphis domestica	92.79	0.00e+00	1049.00
IUUC-Mmu-064035	Mus musculus	92.32	0.00e+00	1032.00
IUUC-Mpu-066726	Mustela putorius furo	92.97	0.00e+00	1053.00
IUUC-Mlu-067020	Myotis lucifugus	92.61	0.00e+00	1049.00
IUUC-Nle-069456	Nomascus leucogenys	92.61	0.00e+00	1050.00
IUUC-Opr-071130	Ochotona princeps	83.06	0.00e+00	912.00
IUUC-Ont-072219	Oreochromis niloticus	82.52	0.00e+00	900.00
IUUC-Oan-073699	Ornithorhynchus anatinus	91.34	0.00e+00	942.00
IUUC-Ocu-074045	Oryctolagus cuniculus	92.61	0.00e+00	1049.00
IUUC-Oga-088494	Otolemur garnettii	92.61	0.00e+00	1051.00
IUUC-Oar-089645	Ovis aries	92.79	0.00e+00	1050.00
IUUC-Ptr-091063	Pan troglodytes	92.61	0.00e+00	1050.00
IUUC-Psi-093946	Pelodiscus sinensis	92.64	0.00e+00	1055.00
IUUC-Pma-094177	Petromyzon marinus	75.84	0.00e+00	797.00
IUUC-Ppa-095956	Physcomitrella patens	26.42	8.00e-15	75.10
IUUC-Pfo-096817	Poecilia formosa	81.80	0.00e+00	916.00
IUUC-Pab-097768	Pongo abelii	92.61	0.00e+00	1048.00
IUUC-Pca-100607	Procavia capensis	75.10	0.00e+00	717.00
IUUC-Pva-102218	Pteropus vampyrus	86.67	0.00e+00	967.00
IUUC-Rno-105250	Rattus norvegicus	92.61	0.00e+00	1048.00
IUUC-Sar-113249	Sorex araneus	92.12	0.00e+00	1026.00
IUUC-Sre-115091	Sporisorium reilianum	53.12	6.10e-01	29.60
IUUC-Ssc-115423	Sus scrofa	92.79	0.00e+00	1052.00
IUUC-Tgu-117050	Taeniopygia guttata	99.46	0.00e+00	1088.00
IUUC-Tru-118239	Takifugu rubripes	81.65	0.00e+00	944.00
IUUC-Tsy-119377	Tarsius syrichta	79.10	0.00e+00	893.00
IUUC-Tni-120122	Tetraodon nigroviridis	80.62	0.00e+00	866.00
IUUC-Vpa-130707	Vicugna pacos	88.63	0.00e+00	835.00
IUUC-Xtr-132035	Xenopus tropicalis	86.51	0.00e+00	1006.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence