iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115773

Ensembl Protein ID

ENSSSCP00000026284.1

UniProt Accession

I3LQA6; I3LQA6_PIG

Genbank Protein ID

ENSSSCP00000026284

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

FP312783

Gene Name

AIRE

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000025294.1	ENSSSCT00000030488.1	ENSSSCP00000026284.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.90e-15	57.0	305	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           + C+vC++gge    l++C+ C ++fH aCl+++  ++ p+ + w C++C 
   Q: 305  DECAVCRDGGE----LICCDGCPRAFHLACLSPP-LRDIPSGT-WRCSSCL 349
           57*********....*******************.*******6.******6 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

RAGGDAALRR LLRLHRTEIA VAVDSAFPLL HALADHEVVP EDKFQETLRL KEKEGCSQAF 60
HALLSWLLTR DTAVILDFWR VLFKDYNLER YARLQPILDS FPKDVDLSQP RKARKPLASS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTGCGGGTG GGGACGCCGC GCTGCGCCGC CTCCTGAGGC TGCACCGCAC GGAGATCGCG 60
GTGGCGGTGG ACAGCGCCTT CCCGCTGCTG CACGCGCTGG CCGACCACGA AGTGGTCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008087--AIRE
IPR004865--HSR_dom
IPR000770--SAND_dom
IPR010919--SAND_dom-like
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51414--HSR
PS50864--SAND
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF03172--HSR
PF00628--PHD
PF01342--SAND

PRINTS

PR01711--AIREGULATOR

SMART

SM00249--PHD
SM00258--SAND

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0042393--F:histone binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003712--F:transcription cofactor activity
GO:0045182--F:translation regulator activity
GO:0008270--F:zinc ion binding
GO:0002509--P:central tolerance induction to self antigen
GO:0032602--P:chemokine production
GO:0006959--P:humoral immune response
GO:0006955--P:immune response
GO:0045060--P:negative thymic T cell selection
GO:0002458--P:peripheral T cell tolerance induction
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000410--P:regulation of thymocyte migration
GO:0097536--P:thymus epithelium morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001612	Ailuropoda melanoleuca	74.79	0.00e+00	690.00
IUUC-Aca-004543	Anolis carolinensis	67.74	7.00e-24	100.00
IUUC-Bta-012988	Bos taurus	79.37	0.00e+00	725.00
IUUC-Bci-013636	Botrytis cinerea	26.53	4.00e-10	60.50
IUUC-Bdi-014663	Brachypodium distachyon	59.57	2.00e-13	71.60
IUUC-Cja-019486	Callithrix jacchus	67.54	3.00e-98	351.00
IUUC-Cfa-021069	Canis familiaris	75.74	0.00e+00	667.00
IUUC-Cpo-021649	Cavia porcellus	67.25	1.00e-159	555.00
IUUC-Csa-023960	Chlorocebus sabaeus	75.45	1.00e-171	595.00
IUUC-Dre-028583	Danio rerio	41.47	1.00e-55	210.00
IUUC-Dno-029869	Dasypus novemcinctus	66.44	1.00e-143	503.00
IUUC-Dor-030263	Dipodomys ordii	84.04	8.00e-45	173.00
IUUC-Ete-032778	Echinops telfairi	88.18	8.00e-47	181.00
IUUC-Eca-034328	Equus caballus	77.13	0.00e+00	668.00
IUUC-Fca-035400	Felis catus	74.87	0.00e+00	677.00
IUUC-Fal-036644	Ficedula albicollis	44.82	1.00e-70	259.00
IUUC-Fox-038014	Fusarium oxysporum	37.50	2.00e-09	58.50
IUUC-Fso-038262	Fusarium solani	40.35	3.00e-09	57.80
IUUC-Ggr-039977	Gaeumannomyces graminis	37.80	2.00e-10	62.00
IUUC-Ggo-045250	Gorilla gorilla	75.14	8.00e-178	616.00
IUUC-Hsa-046603	Homo sapiens	75.31	3.00e-179	621.00
IUUC-Hvu-047073	Hordeum vulgare	56.52	3.00e-13	70.90
IUUC-Itr-048977	Ictidomys tridecemlineatus	73.29	5.00e-174	603.00
IUUC-Lch-050310	Latimeria chalumnae	40.96	2.00e-91	329.00
IUUC-Loc-052508	Lepisosteus oculatus	37.66	1.00e-87	316.00
IUUC-Lma-053053	Leptosphaeria maculans	27.65	5.00e-15	76.60
IUUC-Laf-054028	Loxodonta africana	68.47	3.00e-168	585.00
IUUC-Mcc-054935	Macaca mulatta	74.91	0.00e+00	638.00
IUUC-Mpo-057458	Magnaporthe poae	36.90	2.00e-10	61.60
IUUC-Mga-059318	Meleagris gallopavo	42.94	1.00e-52	199.00
IUUC-Mmr-061557	Microcebus murinus	61.94	6.00e-144	503.00
IUUC-Mdo-062475	Monodelphis domestica	50.44	6.00e-125	440.00
IUUC-Mmu-063994	Mus musculus	71.05	0.00e+00	700.00
IUUC-Mpu-066347	Mustela putorius furo	78.57	0.00e+00	745.00
IUUC-Mlu-068239	Myotis lucifugus	65.31	5.00e-102	363.00
IUUC-Nle-069544	Nomascus leucogenys	90.74	1.00e-25	109.00
IUUC-Opr-071199	Ochotona princeps	71.94	8.00e-71	261.00
IUUC-Ont-072571	Oreochromis niloticus	30.66	3.00e-36	145.00
IUUC-Oan-073739	Ornithorhynchus anatinus	52.81	1.00e-141	496.00
IUUC-Ogl-077865	Oryza glaberrima	41.03	9.00e-13	69.30
IUUC-Olo-080499	Oryza longistaminata	41.03	1.00e-12	69.30
IUUC-Opu-083209	Oryza punctata	42.42	2.00e-12	68.90
IUUC-Oru-084558	Oryza rufipogon	56.00	2.30e-02	35.00
IUUC-Ola-086528	Oryzias latipes	35.52	7.00e-44	171.00
IUUC-Oga-088353	Otolemur garnettii	74.18	0.00e+00	703.00
IUUC-Oar-090065	Ovis aries	79.03	6.00e-158	550.00
IUUC-Ptr-091347	Pan troglodytes	74.95	5.00e-173	600.00
IUUC-Pan-092423	Papio anubis	74.19	0.00e+00	636.00
IUUC-Psi-093798	Pelodiscus sinensis	49.45	3.00e-124	438.00
IUUC-Pfo-096145	Poecilia formosa	72.22	7.00e-21	94.70
IUUC-Pab-098369	Pongo abelii	77.61	8.00e-120	423.00
IUUC-Pca-100537	Procavia capensis	71.17	0.00e+00	645.00
IUUC-Ppe-101215	Prunus persica	60.42	2.00e-14	74.30
IUUC-Pva-102639	Pteropus vampyrus	77.43	0.00e+00	682.00
IUUC-Rno-105285	Rattus norvegicus	70.87	0.00e+00	709.00
IUUC-Sha-107159	Sarcophilus harrisii	48.94	1.00e-125	443.00
IUUC-Spo-108017	Schizosaccharomyces pombe	29.89	5.00e-11	62.40
IUUC-Sit-110355	Setaria italica	62.50	1.00e-13	72.00
IUUC-Sbi-113930	Sorghum bicolor	62.50	1.00e-13	72.40
IUUC-Tgu-116922	Taeniopygia guttata	48.56	2.00e-68	252.00
IUUC-Tru-118263	Takifugu rubripes	29.62	6.00e-55	207.00
IUUC-Tsy-119270	Tarsius syrichta	68.27	5.00e-91	328.00
IUUC-Tni-120138	Tetraodon nigroviridis	31.21	3.00e-58	219.00
IUUC-Tca-121757	Theobroma cacao	52.83	8.00e-14	73.20
IUUC-Tae-124715	Triticum aestivum	56.52	4.00e-13	70.90
IUUC-Tme-127204	Tuber melanosporum	53.19	2.00e-13	71.60
IUUC-Tbe-128077	Tupaia belangeri	70.11	0.00e+00	694.00
IUUC-Ttr-128781	Tursiops truncatus	78.53	8.00e-78	284.00
IUUC-Xma-133054	Xiphophorus maculatus	28.83	4.00e-53	202.00
IUUC-Yli-134436	Yarrowia lipolytica	35.14	3.00e-12	66.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence